Martín Schuster
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View article: Population-level bistability in <i>Pseudomonas aeruginosa</i> quorum sensing
Population-level bistability in <i>Pseudomonas aeruginosa</i> quorum sensing Open
Quorum sensing (QS) is a widespread signaling mechanism in bacteria that coordinates collective behaviors according to population density. A foundational assumption in this field is that QS functions as a gene expression switch that synchr…
View article: Mycobacterium abscessus persistence in the face of Pseudomonas aeruginosa antagonism
Mycobacterium abscessus persistence in the face of Pseudomonas aeruginosa antagonism Open
Introduction Chronic bacterial infections are responsible for significant morbidity and mortality in cystic fibrosis (CF) patients. Pseudomonas aeruginosa ( Pa ), the dominant CF pathogen, and Mycobacterium abscessus ( Mab ) can individual…
View article: IFN-γ/IL-2 Double-Color FluoroSpot Assay for Monitoring Human Primary T Cell Activation: Validation, Inter-Laboratory Comparison, and Recommendations for Clinical Studies
IFN-γ/IL-2 Double-Color FluoroSpot Assay for Monitoring Human Primary T Cell Activation: Validation, Inter-Laboratory Comparison, and Recommendations for Clinical Studies Open
The enzyme-linked immunosorbent spot (EliSpot) assay and its fluorescence-based version, FluoroSpot, are sensitive immunoassays commonly used to quantify antigen-specific T and B lymphocytes and other immune cells in peripheral blood or ho…
View article: <i>Mycobacterium abscessus</i>persistence in the face of<i>Pseudomonas aeruginosa</i>antagonism
<i>Mycobacterium abscessus</i>persistence in the face of<i>Pseudomonas aeruginosa</i>antagonism Open
Chronic bacterial infections are responsible for significant mortality and morbidity in cystic fibrosis (CF) patients. Pseudomonas aeruginosa ( Pa ), the dominant CF pathogen, and Mycobacterium abscessus ( Mab ) both cause persistent pulmo…
View article: Putting theory to the test: An integrated computational/experimental chemostat model of the tragedy of the commons
Putting theory to the test: An integrated computational/experimental chemostat model of the tragedy of the commons Open
Cooperation via shared public goods is ubiquitous in nature, however, noncontributing social cheaters can exploit the public goods provided by cooperating individuals to gain a fitness advantage. Theory predicts that this dynamic can cause…
View article: Glossar zu Prozesszeiten und Kennzahlen im Herzkatheterlabor
Glossar zu Prozesszeiten und Kennzahlen im Herzkatheterlabor Open
Zusammenfassung Der demografische Wandel sowie innovative Fortschritte in der interventionellen Kardiologie führen zu Veränderungen in der Qualität der medizinischen Versorgung von Patienten mit kardiovaskulären Erkrankungen. Ein erfolgrei…
View article: Parameters, architecture and emergent properties of the <i>Pseudomonas aeruginosa</i> LasI/LasR quorum-sensing circuit
Parameters, architecture and emergent properties of the <i>Pseudomonas aeruginosa</i> LasI/LasR quorum-sensing circuit Open
Quorum sensing is a widespread process in bacteria that controls collective behaviours in response to cell density. Populations of cells coordinate gene expression through the perception of self-produced chemical signals. Although this pro…
View article: Putting theory to the test: an integrated computational/experimental chemostat model of the Tragedy of the Commons - raw data
Putting theory to the test: an integrated computational/experimental chemostat model of the Tragedy of the Commons - raw data Open
Raw data for manuscript titled: Putting theory to the test: An integrated computational/experimental chemostat model of the Tragedy of the Commons. Empirical data is in the excel file tocpa_masterraw.xlsx. Each tab of the excel file…
View article: Development and Evaluation of an Anonymity-Focused Feedback Tool Based on Ring Signatures
Development and Evaluation of an Anonymity-Focused Feedback Tool Based on Ring Signatures Open
A feedback system should be developed for the Blockchain Academy Mittweida, which can store the feedback for the courses offered anonymously and without duplication. It should be possible, without removing the anonymity of the users, to de…
View article: Antiactivators prevent self-sensing in <i>Pseudomonas aeruginosa</i> quorum sensing
Antiactivators prevent self-sensing in <i>Pseudomonas aeruginosa</i> quorum sensing Open
Quorum sensing is described as a widespread cell density-dependent signaling mechanism in bacteria. Groups of cells coordinate gene expression by secreting and responding to diffusible signal molecules. Theory, however, predicts that indiv…
View article: Inexpensive Apparatus for High-Quality Imaging of Microbial Growth on Agar Plates
Inexpensive Apparatus for High-Quality Imaging of Microbial Growth on Agar Plates Open
The ability to capture images of results or processes is an important tool in the biologist’s tool kit. In microbiology, capturing high-quality images of microbial growth on agar plates is difficult due to the reflective surface of the pla…
View article: A Discrete SIR Model with Spatial Distribution on a Torus for COVID-19 Analysis using Local Neighborhood Properties
A Discrete SIR Model with Spatial Distribution on a Torus for COVID-19 Analysis using Local Neighborhood Properties Open
The ongoing COVID-19 pandemic threatens the health of humans, causes great economic losses and may disturb the stability of the societies Mathematical models can be used to understand aspects of the dynamics of epidemics and to increase t…
View article: Cooperation and Cheating through a Secreted Aminopeptidase in the Pseudomonas aeruginosa RpoS Response
Cooperation and Cheating through a Secreted Aminopeptidase in the Pseudomonas aeruginosa RpoS Response Open
Bacterial stress responses are generally considered protective measures taken by individual cells. Enabled by an experimental evolution approach, we describe a contrasting property, collective nutrient acquisition, in the RpoS-dependent st…
View article: IT-structures and Algorithms for Quality Assurance in the Health Insurance Medical Advisory Service Institutions in Germany
IT-structures and Algorithms for Quality Assurance in the Health Insurance Medical Advisory Service Institutions in Germany Open
View article: Interrelations between Drug Prescriptions and Diagnoses for SHI Diabetes Patients using Graph Theoretic Methods and a Markov Model
Interrelations between Drug Prescriptions and Diagnoses for SHI Diabetes Patients using Graph Theoretic Methods and a Markov Model Open
View article: Updating graph databases with Cypher
Updating graph databases with Cypher Open
The paper describes the present and the future of graph updates in Cypher, the language of the Neo4j property graph database and several other products. Update features include those with clear analogs in relational databases, as well as t…
View article: Bacterial Cheaters Evade Punishment by Cyanide
Bacterial Cheaters Evade Punishment by Cyanide Open
In all domains of life, mechanisms exist that protect cooperating groups from exploitation by cheaters. Recent observations with the bacterium Pseudomonas aeruginosa have suggested a paradigmatic cheater control mechanism in which cooperat…
View article: Public goods and cheating in microbes
Public goods and cheating in microbes Open
View article: Homogeneous and Heterogeneous Response of Quorum-Sensing Bacteria in an Evolutionary Context
Homogeneous and Heterogeneous Response of Quorum-Sensing Bacteria in an Evolutionary Context Open
To explain the stability of cooperation is a central task of evolutionary theory. We investigate this question in the case of quorum sensing (QS) bacteria, which regulate cooperative traits in response to population density. Cooperation is…
View article: Strong cooperation or tragedy of the commons in the chemostat
Strong cooperation or tragedy of the commons in the chemostat Open
In [11], a proof of principle was established for the phenomenon of the tragedy of the commons, a center piece for many theories on the evolution of cooperation. A general chemostat model with two species, the cooperator and the cheater, w…
View article: Streaming Rewriting Games: Winning Strategies and Complexity
Streaming Rewriting Games: Winning Strategies and Complexity Open
Context-free games on strings are two-player rewriting games based on a set of production rules and a regular target language. In each round, the first player selects a position of the current string; then the second player replaces the sy…
View article: Formal Semantics of the Language Cypher
Formal Semantics of the Language Cypher Open
Cypher is a query language for property graphs. It was originally designed and implemented as part of the Neo4j graph database, and it is currently used in a growing number of commercial systems, industrial applications and research projec…
View article: Additive Effects of Quorum Sensing Anti-Activators on Pseudomonas aeruginosa Virulence Traits and Transcriptome
Additive Effects of Quorum Sensing Anti-Activators on Pseudomonas aeruginosa Virulence Traits and Transcriptome Open
In the opportunistic pathogen Pseudomonas aeruginosa, quorum sensing (QS) via acyl-homoserine lactone (AHL) signals coordinates virulence gene expression. AHL signals must reach a critical threshold before enough is bound by cognate…
View article: Extracting Information and Identifying Data Structures in Pharmacological Big Data using Gawk
Extracting Information and Identifying Data Structures in Pharmacological Big Data using Gawk Open
View article: Tragedy of the commons in the chemostat
Tragedy of the commons in the chemostat Open
We present a proof of principle for the phenomenon of the tragedy of the commons that is at the center of many theories on the evolution of cooperation. Whereas the tragedy is commonly set in a game theoretical context, and attributed to a…
View article: Tomasz Torbus, Markus Hörsch (Hrsg.), Architektur und Kunst in der Ära des sächsischen Ministers Heinrich Graf von Brühl (1738-1763)
Tomasz Torbus, Markus Hörsch (Hrsg.), Architektur und Kunst in der Ära des sächsischen Ministers Heinrich Graf von Brühl (1738-1763) Open
View article: Nutrient limitation determines the fitness of cheaters in bacterial siderophore cooperation
Nutrient limitation determines the fitness of cheaters in bacterial siderophore cooperation Open
Cooperative behaviors provide a collective benefit, but are considered costly for the individual. Here, we report that these costs vary dramatically in different contexts and have opposing effects on the selection for non-cooperating cheat…
View article: Corrigendum: Why Quorum Sensing Controls Private Goods
Corrigendum: Why Quorum Sensing Controls Private Goods Open
[This corrects the article on p. 885 in vol. 8, PMID: 28579979.].
View article: Valuation of Combined Wind Power Plant and Hydrogen Storage: A Decision Tree Approach
Valuation of Combined Wind Power Plant and Hydrogen Storage: A Decision Tree Approach Open
This article analyses the profitability of a wind power plant in combination with a hydrogen storage. We distinguish between off- and on-shore locations with a 50 MW unit. The hydrogen of the storage unit can be used to either be re-electr…
View article: Tragedy of the Commons in the Chemostat
Tragedy of the Commons in the Chemostat Open
We present a proof of principle for the phenomenon of the tragedy of the commons that is at the center of many theories on the evolution of cooperation. We establish the tragedy in the context of a general chemostat model with two species,…