Martin Südmeyer
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View article: Quantity, Quality and Staffs’ Knowledge in Long‐Term Nursing Care in People with Parkinson’s Disease – “Real‐Life” Results from the German Care4PD Study
Quantity, Quality and Staffs’ Knowledge in Long‐Term Nursing Care in People with Parkinson’s Disease – “Real‐Life” Results from the German Care4PD Study Open
Background/Objectives: About 20% of people with Parkinson’s Disease (PwP) in Germany need a professional long-term care (LTC). Previous data indicated a rather poor LTC situation and the need for profounder analyses. Thus, we aimed at diss…
View article: Real-world disease burden and planned treatment optimization after MANAGE-PD implementation in Germany: a cross-sectional study
Real-world disease burden and planned treatment optimization after MANAGE-PD implementation in Germany: a cross-sectional study Open
Background In Germany, the approach to treatment optimization for patients with advanced Parkinson's disease (PD) is considered somewhat conservative. The MANAGE-PD tool ( www.managepd.eu ) was developed to help identify patients with adva…
View article: Reduced awareness of cognitive deficits in idiopathic normal pressure hydrocephalus and its change following lumbar puncture
Reduced awareness of cognitive deficits in idiopathic normal pressure hydrocephalus and its change following lumbar puncture Open
Our study revealed LP-related RACD changes in iNPH patients compared to those in AACS and HC participants. The results suggest a mitigation of impaired metacognitive abilities in iNPH, possibly resulting from LP-induced improvements in (lo…
View article: Utilization of MANAGE-PD Tool in a Real-World Setting in Germany: A Cross-Sectional Study
Utilization of MANAGE-PD Tool in a Real-World Setting in Germany: A Cross-Sectional Study Open
MANAGE-PD is a validated, web-based tool to assist physicians in identifying patients with Parkinson’s disease (PD) whose symptoms are inadequately controlled by oral medication. Also, a modified patient version of MANAGE-PD (Parkinson Che…
View article: The comorbidity profiles and medication issues of patients with multiple system atrophy: a systematic cross-sectional analysis
The comorbidity profiles and medication issues of patients with multiple system atrophy: a systematic cross-sectional analysis Open
View article: Nationwide Retrospective Analysis of Combinations of Advanced Therapies in Patients With Parkinson Disease
Nationwide Retrospective Analysis of Combinations of Advanced Therapies in Patients With Parkinson Disease Open
This study provides Class IV evidence that, in patients with PD, changing or combining ATs is associated with an improvement in the MDS-UPDRS or subjective symptom reporting.
View article: Prospective controlled study on the effects of deep brain stimulation on driving in Parkinson’s disease
Prospective controlled study on the effects of deep brain stimulation on driving in Parkinson’s disease Open
View article: Device-Aided Therapies in Parkinson’s Disease—Results from the German Care4PD Study
Device-Aided Therapies in Parkinson’s Disease—Results from the German Care4PD Study Open
Data on the use of device-aided therapies (DATs) in people with Parkinson’s disease (PwP) are scarce. Analyzing data from the Care4PD patient survey, we (1) evaluated application frequency and type of DAT in a larger, nationwide, cross-sec…
View article: Predictors of post-stroke depression: Validation of established risk factors and introduction of a dynamic perspective in two longitudinal studies
Predictors of post-stroke depression: Validation of established risk factors and introduction of a dynamic perspective in two longitudinal studies Open
Introduction Cerebral insults lead in many cases not only to cognitive impairment but also to disturbed emotionality. After stroke, one in three survivors develops a depression which impacts quality of life and rehabilitation. Meta-analyse…
View article: Effects of deep brain stimulation on driving in Parkinson’s disease - a prospective controlled study
Effects of deep brain stimulation on driving in Parkinson’s disease - a prospective controlled study Open
About 50% of patients with Parkinson’s disease (PD) treated with deep brain stimulation (DBS) actively drive a car. In this controlled, three-armed study, non-demented active drivers with PD and DBS were recruited to prospectively examine …
View article: Comparative analysis of machine learning algorithms for multi-syndrome classification of neurodegenerative syndromes
Comparative analysis of machine learning algorithms for multi-syndrome classification of neurodegenerative syndromes Open
View article: Regional changes of brain structure during progression of idiopathic Parkinson's disease – A longitudinal study using deformation based morphometry
Regional changes of brain structure during progression of idiopathic Parkinson's disease – A longitudinal study using deformation based morphometry Open
Idiopathic Parkinson's disease (PD) is a neurodegenerative disorder with a broad spectrum of motor and non-motor symptoms. The neuropathological characteristics of idiopathic PD are the degeneration of dopaminergic neurons in the striatum,…
View article: Impact of COVID-19 Pandemic on (Health) Care Situation of People with Parkinson’s Disease in Germany (Care4PD)
Impact of COVID-19 Pandemic on (Health) Care Situation of People with Parkinson’s Disease in Germany (Care4PD) Open
The Care4PD study examined the impact of the COVID-19 pandemic on the care situation of people (PwP) with Parkinson’s disease in Germany. A comprehensive, nationwide, anonymous questionnaire for PwP was distributed by the members’ journal …
View article: Heute die gesundheitspolitischen Weichen für morgen stellen
Heute die gesundheitspolitischen Weichen für morgen stellen Open
View article: A case of longitudinally extensive transverse myelitis following vaccination against Covid-19
A case of longitudinally extensive transverse myelitis following vaccination against Covid-19 Open
View article: Within- and across-network alterations of the sensorimotor network in Parkinson’s disease
Within- and across-network alterations of the sensorimotor network in Parkinson’s disease Open
View article: Funktion und Dysfunktion motorischer Netzwerke
Funktion und Dysfunktion motorischer Netzwerke Open
View article: Comparative Analysis of Machine Learning Algorithms for Multi-Syndrome Classification of Neurodegenerative Syndromes
Comparative Analysis of Machine Learning Algorithms for Multi-Syndrome Classification of Neurodegenerative Syndromes Open
Importance The entry of artificial intelligence into medicine is pending. Several methods have been used for predictions of structured neuroimaging data, yet nobody compared them in this context.Objective Multi-class prediction is key for …
View article: Investigating the 1-year decline in midbrain-to-pons ratio in the differential diagnosis of PSP and IPD
Investigating the 1-year decline in midbrain-to-pons ratio in the differential diagnosis of PSP and IPD Open
Background A reliable measure of PSP-specific midbrain atrophy, the midbrain-to-pons ratio (MTPR) has been reported to support the differential diagnosis of progressive supranuclear palsy (PSP) from idiopathic Parkinson’s disease (IPD). Si…
View article: Somatosensory area 3b is selectively unaffected in corticobasal syndrome: combining MRI and histology
Somatosensory area 3b is selectively unaffected in corticobasal syndrome: combining MRI and histology Open
An increasing number of neuroimaging studies addressing patients with corticobasal syndrome use macroscopic definitions of brain regions. As a closer link to functionally relevant units, we aimed at identifying magnetic resonance-based atr…
View article: Pallidal Deep Brain Stimulation Reduces Sensorimotor Cortex Activation in Focal/Segmental Dystonia
Pallidal Deep Brain Stimulation Reduces Sensorimotor Cortex Activation in Focal/Segmental Dystonia Open
Background Although deep brain stimulation of the globus pallidus internus (GPi‐DBS) is an established treatment for many forms of dystonia, including generalized as well as focal forms, its effects on brain (dys‐)function remain to be elu…
View article: Safety and efficacy of epigallocatechin gallate in multiple system atrophy (PROMESA): a randomised, double-blind, placebo-controlled trial
Safety and efficacy of epigallocatechin gallate in multiple system atrophy (PROMESA): a randomised, double-blind, placebo-controlled trial Open
BACKGROUND Multiple system atrophy is a rare neurodegenerative disease characterised by aggregation of \\textgreeka-synuclein in oligodendrocytes and neurons. The polyphenol epigallocatechin gallate inhibits \\textgreeka-synuclein aggregat…
View article: Machine-learning identifies Parkinson's disease patients based on resting-state between-network functional connectivity
Machine-learning identifies Parkinson's disease patients based on resting-state between-network functional connectivity Open
Objective: Evaluation of a data-driven, model-based classification approach to discriminate idiopathic Parkinson’s disease (PD) patients from healthy controls (HC) based on between-network connectivity in whole-brain resting-state function…
View article: Quality of life predicts outcome of deep brain stimulation in early Parkinson disease
Quality of life predicts outcome of deep brain stimulation in early Parkinson disease Open
NCT00354133.
View article: Pre-stimulus beta power modulation during motor sequence learning is reduced in 'Parkinson's disease
Pre-stimulus beta power modulation during motor sequence learning is reduced in 'Parkinson's disease Open
View article: Corrigendum to “On the integrity of functional brain networks in schizophrenia, Parkinson's disease, and advanced age: Evidence from connectivity‐based single‐subject classification.”
Corrigendum to “On the integrity of functional brain networks in schizophrenia, Parkinson's disease, and advanced age: Evidence from connectivity‐based single‐subject classification.” Open
View article: Functional Connectivity Changes of Key Regions for Motor Initiation in Parkinson’s Disease
Functional Connectivity Changes of Key Regions for Motor Initiation in Parkinson’s Disease Open
Akinesia, a cardinal symptom of Parkinson's disease, has been linked to abnormal activation in putamen and posterior medial frontal cortex (pMFC). However, little is known whether clinical severity of akinesia is linked to dysfunctional co…
View article: Neurostimulation in tardive dystonia/dyskinesia: A delayed start, sham stimulation-controlled randomized trial
Neurostimulation in tardive dystonia/dyskinesia: A delayed start, sham stimulation-controlled randomized trial Open
View article: Behavioural outcomes of subthalamic stimulation and medical therapy versus medical therapy alone for Parkinson's disease with early motor complications (EARLYSTIM trial): secondary analysis of an open-label randomised trial
Behavioural outcomes of subthalamic stimulation and medical therapy versus medical therapy alone for Parkinson's disease with early motor complications (EARLYSTIM trial): secondary analysis of an open-label randomised trial Open
View article: The significance of brain oscillations in motor sequence learning: Insights from Parkinson's disease
The significance of brain oscillations in motor sequence learning: Insights from Parkinson's disease Open
Motor sequence learning plays a pivotal role in various everyday activities. Motor-cortical beta oscillations have been suggested to be involved in this type of learning. In Parkinson's disease (PD), oscillatory activity within cortico-bas…