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View article: Analyzing the ‘Bradykinesia Complex’ in Parkinson's Disease
Analyzing the ‘Bradykinesia Complex’ in Parkinson's Disease Open
Background Bradykinesia is the hallmark sign of parkinsonism. We recently proposed redefining bradykinesia as a complex of motor abnormalities, each reflecting separate pathophysiological elements. Objective To analyze the ‘bradykinesia co…
Visual <span>DAT</span>‐<span>SPECT</span> Outperforms Semiquantitative Analysis in a “Pseudo‐<span>SWEDD”</span> Case of Benign Tremulous Parkinsonism Open
No abstract available
Pathophysiological Role of Primary Motor Cortex in Essential Tremor Open
Background Essential tremor (ET) is one of the most prevalent movement disorders. However, the complete understanding of ET pathophysiology remains elusive. Objective To explore the pathophysiological role of primary motor cortex (M1) in E…
View article: Neurophysiological markers of motor compensatory mechanisms in early Parkinson’s disease
Neurophysiological markers of motor compensatory mechanisms in early Parkinson’s disease Open
Compensatory mechanisms in Parkinson’s disease are defined as the changes that the brain uses to adapt to neurodegeneration and progressive dopamine reduction. Motor compensation in early Parkinson’s disease could, in part, be responsible …
The Whistle‐Smile Reflex in Parkinson's Disease: A Cross‐Sectional Study Open
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The Role of Non-Invasive Brain Modulation in Identifying Disease Biomarkers for Diagnostic and Therapeutic Purposes in Parkinsonism Open
Over the past three decades, substantial advancements have occurred in non-invasive brain stimulation (NIBS). These developments encompass various non-invasive techniques aimed at modulating brain function. Among the most widely utilized m…
Insight Into the Relationship Between Motor and Cognitive Symptoms in Essential Tremor Open
Introduction:Essential tremor (ET) is a heterogeneous disorder characterized by bilateral upper limbs action tremor and, possibly, neurological signs of uncertain significance, including voluntary movement abnormalities and cognitive distu…
A Novel KCNQ2 Variant in a Patient with a Combined Tremor Syndrome Open
The KCNQ2 protein regulates action potential firing, and mutations in its gene are associated with epilepsy and neuropathic pain. The identified variant, although of uncertain significance, may disrupt KCNQ2 function and also play a role i…
Interhemispheric imbalance and bradykinesia features in Parkinson’s disease Open
In patients with Parkinson’s disease, the connectivity between the two primary motor cortices may be altered. However, the correlation between asymmetries of abnormal interhemispheric connections and bradykinesia features has not been inve…