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View article: Management and Outcomes of Invasive Procedures in Individuals with Hemophilia A on Emicizumab Prophylaxis: A Single Center Experience
Management and Outcomes of Invasive Procedures in Individuals with Hemophilia A on Emicizumab Prophylaxis: A Single Center Experience Open
Prophylactic treatment with emicizumab has become an important and effective bleeding prevention for people with hemophilia A (PwHA). Perioperative management of PwHA using emicizumab prophylaxis is still challenging due to a lack of exper…
View article: Practice of neuromonitoring in open and endovascular thoracoabdominal aortic repair—an international expert-based modified Delphi consensus study
Practice of neuromonitoring in open and endovascular thoracoabdominal aortic repair—an international expert-based modified Delphi consensus study Open
OBJECTIVES Spinal cord injury is detrimental for patients undergoing open or endovascular thoracoabdominal aortic aneurysm (TAAA) repair. The aim of this survey and of the modified Delphi consensus was to gather information on current prac…
View article: A Multicenter Clinical Diagnostic Accuracy Study of SureStatus, an Affordable, WHO Emergency Use-Listed, Rapid, Point-Of-Care Antigen-Detecting Diagnostic Test for SARS-CoV-2
A Multicenter Clinical Diagnostic Accuracy Study of SureStatus, an Affordable, WHO Emergency Use-Listed, Rapid, Point-Of-Care Antigen-Detecting Diagnostic Test for SARS-CoV-2 Open
Our manufacturer-independent, prospective diagnostic accuracy study assessed clinical performance in participants presumed to have a SARS-CoV-2 infection at three study sites in two countries. We assessed the accuracy overall and in predef…
View article: Evaluation of accuracy, exclusivity, limit-of-detection and ease-of-use of LumiraDx™: An antigen-detecting point-of-care device for SARS-CoV-2
Evaluation of accuracy, exclusivity, limit-of-detection and ease-of-use of LumiraDx™: An antigen-detecting point-of-care device for SARS-CoV-2 Open
View article: Identification of Variants Associated With Rare Hematological Disorder Erythrocytosis Using Targeted Next-Generation Sequencing Analysis
Identification of Variants Associated With Rare Hematological Disorder Erythrocytosis Using Targeted Next-Generation Sequencing Analysis Open
An erythrocytosis is present when the red blood cell mass is increased, demonstrated as elevated hemoglobin and hematocrit in the laboratory evaluation. Congenital predispositions for erythrocytosis are rare, with germline variants in seve…
View article: Corrigendum to ‘Impact of the coronavirus disease 2019 (COVID-19) pandemic on the care of patients with acute and chronic aortic conditions’
Corrigendum to ‘Impact of the coronavirus disease 2019 (COVID-19) pandemic on the care of patients with acute and chronic aortic conditions’ Open
In the original version of this article, the first name of author Vitaly Sorokin was misspelled. This has now been corrected above and in the full article.
View article: Diagnosis and management of non-clonal erythrocytosis remains challenging: a single centre clinical experience
Diagnosis and management of non-clonal erythrocytosis remains challenging: a single centre clinical experience Open
Erythrocytosis has a diverse background. While polycythaemia vera has well defined criteria, the diagnostic approach and management of other types of erythrocytosis are more challenging. The aim of study was to retrospectively analyse the …
View article: Genetic analysis of 39 erythrocytosis and hereditary hemochromatosis‐associated genes in the Slovenian family with idiopathic erythrocytosis
Genetic analysis of 39 erythrocytosis and hereditary hemochromatosis‐associated genes in the Slovenian family with idiopathic erythrocytosis Open
Background Erythrocytosis is a condition with an excessive number of erythrocytes, accompanied by an elevated haemoglobin and/or haematocrit value. Congenital erythrocytosis has a diverse genetic background with several genes involved in e…
View article: Impact of the coronavirus disease 2019 (COVID-19) pandemic on the care of patients with acute and chronic aortic conditions
Impact of the coronavirus disease 2019 (COVID-19) pandemic on the care of patients with acute and chronic aortic conditions Open
OBJECTIVES To evaluate the impact of the coronavirus disease 2019 (COVID-19) pandemic on acute and elective thoracic and abdominal aortic procedures. METHODS Forty departments shared their data on acute and elective thoracic and abdominal …
View article: Increase of Dose Associated With Decrease in Protection Against Controlled Human Malaria Infection by PfSPZ Vaccine in Tanzanian Adults
Increase of Dose Associated With Decrease in Protection Against Controlled Human Malaria Infection by PfSPZ Vaccine in Tanzanian Adults Open
Background A vaccine would be an ideal tool for reducing malaria’s impact. PfSPZ Vaccine (radiation attenuated, aseptic, purified, cryopreserved Plasmodium falciparum [Pf] sporozoites [SPZ]) has been well tolerated and safe in >1526 mal…
View article: A multiplex qPCR approach for detection of pfhrp2 and pfhrp3 gene deletions in multiple strain infections of Plasmodium falciparum
A multiplex qPCR approach for detection of pfhrp2 and pfhrp3 gene deletions in multiple strain infections of Plasmodium falciparum Open
The rapid and accurate diagnosis of Plasmodium falciparum malaria infection is an essential factor in malaria control. Currently, malaria diagnosis in the field depends heavily on using rapid diagnostic tests (RDTs) many of which detect ci…
View article: Opredelitev eritrocitoz in predlog diagnostičnega algoritma v Sloveniji
Opredelitev eritrocitoz in predlog diagnostičnega algoritma v Sloveniji Open
Eritrocitoza je stanje s povečano maso eritrocitov v telesu. Odrazi se s povečanim hematokritom, zvečano koncentracijo hemoglobina in povečanim številom eritrocitov v krvi. Ločimo absolutno in relativno eritrocitozo. Absolutne oblike pa na…
View article: Safety and Differential Antibody and T-Cell Responses to the Plasmodium falciparum Sporozoite Malaria Vaccine, PfSPZ Vaccine, by Age in Tanzanian Adults, Adolescents, Children, and Infants
Safety and Differential Antibody and T-Cell Responses to the Plasmodium falciparum Sporozoite Malaria Vaccine, PfSPZ Vaccine, by Age in Tanzanian Adults, Adolescents, Children, and Infants Open
In 2016, there were more cases and deaths caused by malaria globally than in 2015. An effective vaccine would be an ideal additional tool for reducing malaria’s impact. Sanaria ® PfSPZ Vaccine, composed of radiation-attenuated, aseptic, pu…
View article: Slovenska priporočila za obravnavo kronične mieloične levkemije
Slovenska priporočila za obravnavo kronične mieloične levkemije Open
The paper presents recommendations for the management of patients with chronic myeloid leukaemia. Clinical manifestations, diagnostics, treatment and monitoring of treatment are presented.
View article: High-fat medium and circadian transcription factors (cryptochrome and clock) contribute to the regulation of cholesterogenic Cyp51 and Hmgcr genes in mouse embryonic fibroblasts
High-fat medium and circadian transcription factors (cryptochrome and clock) contribute to the regulation of cholesterogenic Cyp51 and Hmgcr genes in mouse embryonic fibroblasts Open
The aim of our research was to investigate how cholesterol, unsaturated fatty acids and circadian genes affect the expression of cholesterogenic genes, Cyp51 and Hmgcr, in somatic and in embryonic fibroblast cell lines. We found that in im…