Martinus Theodorus van de Bilt
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View article: Negative symptoms and self-reflection increase alienation in individuals at clinical high-risk for psychosis
Negative symptoms and self-reflection increase alienation in individuals at clinical high-risk for psychosis Open
Objective To assess stigma and cognitive insight, and their interplay with symptoms in individuals at clinical high risk for psychosis (CHR). Methods Individuals were screened for CHR status and then assessed with the Internalized Stigma o…
View article: Screening the Community for Individuals at Clinical High Risk (<scp>CHR</scp>) for Psychosis
Screening the Community for Individuals at Clinical High Risk (<span>CHR</span>) for Psychosis Open
Introduction The aim of our study was to assess the performance of the Prodromal Questionnaire‐16 (PQ‐16) and the Perceptual and Cognitive Aberrations scale (PCA) to screen for clinical high risk for psychosis (CHR) in a sample of nonhelp‐…
View article: Automated movement analysis predicts transition to non-psychotic disorders in individuals at ultra-high risk for psychosis
Automated movement analysis predicts transition to non-psychotic disorders in individuals at ultra-high risk for psychosis Open
Baseline movement variability distinguishes ultra-high risk transition outcomes, with higher variability in those who transitioned to non-psychotic disorders. This demonstrates the importance of movement analysis as a potential transition …
View article: Natural language processing in at-risk mental states: enhancing the assessment of thought disorders and psychotic traits with semantic dynamics and graph theory
Natural language processing in at-risk mental states: enhancing the assessment of thought disorders and psychotic traits with semantic dynamics and graph theory Open
Subtle speech impairments can be detected by sensitive methods and can be used in at-risk mental states screening. We have outlined a blueprint for speech-based evaluation, pairing features to standard psychometric items for thought disord…
View article: Detecting at-risk mental states for psychosis (ARMS) using machine learning ensembles and facial features
Detecting at-risk mental states for psychosis (ARMS) using machine learning ensembles and facial features Open
View article: Inequality and barriers in psychosis prevention: A systematic review on clinical high-risk for psychosis studies from developing countries
Inequality and barriers in psychosis prevention: A systematic review on clinical high-risk for psychosis studies from developing countries Open
Background The clinical high-risk for psychosis (CHR) paradigm is one of the best studied preventive paradigms in psychiatry. However, most studies have been conducted in high-income countries. It is unclear if knowledge from such countrie…
View article: A dopamine receptor D2 genetic polymorphism associated with transition to mental disorders in a cohort of individuals with at-risk mental state for psychosis
A dopamine receptor D2 genetic polymorphism associated with transition to mental disorders in a cohort of individuals with at-risk mental state for psychosis Open
Our findings suggest that rs6277 could potentially constitute a genetic marker of transition to psychiatric disorders in subjects with at-risk mental states, warranting further investigation in larger samples.
View article: Motion energy analysis during speech tasks in medication-naïve individuals with at-risk mental states for psychosis
Motion energy analysis during speech tasks in medication-naïve individuals with at-risk mental states for psychosis Open
Movement abnormalities are commonly observed in schizophrenia and at-risk mental states (ARMS) for psychosis. They are usually detected with clinical interviews, such that automated analysis would enhance assessment. Our aim was to use mot…
View article: Association study of 45 SNPs in a non-help seeking cohort sample with at-risk mental state for psychosis
Association study of 45 SNPs in a non-help seeking cohort sample with at-risk mental state for psychosis Open
Background: At-risk mental state for psychosis (ARMS) samples are highly heterogeneous and non-epidemiological, as most of the studies recruit help-seeking patients from specialized clinics. Transition-to-psychosis rates differ among them,…
View article: Detecting At-Risk Mental States for Psychosis (ARMs) in General Population Individuals Using Machine Learning Ensembles and Facial Features
Detecting At-Risk Mental States for Psychosis (ARMs) in General Population Individuals Using Machine Learning Ensembles and Facial Features Open
View article: Translation and validation of the Structured Interview for Prodromal Syndromes (SIPS) to Portuguese
Translation and validation of the Structured Interview for Prodromal Syndromes (SIPS) to Portuguese Open
to neglect COVID-19 safety protocols and underestimate the possibility of getting infected by the virus.The Peltzman effect can be used to explain the increased risk-taking of people post vaccination.According to this theory, when safety m…
View article: Addressing Mood Disorder Diagnosis' Stigma With an Honest, Open, Proud (HOP)-Based Intervention: A Randomized Controlled Trial
Addressing Mood Disorder Diagnosis' Stigma With an Honest, Open, Proud (HOP)-Based Intervention: A Randomized Controlled Trial Open
Introduction: The public stigma and self-stigma contribute to the dilemma of disclosing or not one's own mental illness diagnosis. Studies suggest that revealing it diminishes stress, besides helping with self-esteem. Honest, Open, Proud (…
View article: <p>Treatment of Patients with Recently Exacerbated Schizophrenia with Paliperidone Palmitate: A Pilot Study of Efficacy and Tolerability</p>
Treatment of Patients with Recently Exacerbated Schizophrenia with Paliperidone Palmitate: A Pilot Study of Efficacy and Tolerability Open
Paliperidone palmitate was efficacious in Latin American patients studied with an acute exacerbation and recent diagnosis of schizophrenia, and no new safety signals were identified.
View article: Influence of migration on the thought process of individuals at ultra-high risk for psychosis
Influence of migration on the thought process of individuals at ultra-high risk for psychosis Open
Our data reinforce migration as a risk factor for psychosis in developing countries as well, and highlights the importance of studying the specific effect of this factor in UHR psychopathology.
View article: F42. COGNITIVE PATTERNS ASSOCIATED WITH CHILDHOOD TRAUMA AND RISK FOR PSYCHOSIS IN A POPULATIONAL SAMPLE–A LATENT PROFILE ANALYSIS
F42. COGNITIVE PATTERNS ASSOCIATED WITH CHILDHOOD TRAUMA AND RISK FOR PSYCHOSIS IN A POPULATIONAL SAMPLE–A LATENT PROFILE ANALYSIS Open
BACKGROUND: Recent efforts to prevent psychosis tried to identify at risk individuals in the community and in clinical settings. For this purpose, ultra-high risk for psychosis (UHR) and clinical high-risk state for psychosis (CHR-P) crite…
View article: T203. ILLICIT DRUGS USE AND ULTRA-HIGH RISK (UHR) FOR PSYCHOSIS STATUS IN A LATIN-AMERICAN SAMPLE
T203. ILLICIT DRUGS USE AND ULTRA-HIGH RISK (UHR) FOR PSYCHOSIS STATUS IN A LATIN-AMERICAN SAMPLE Open
In recent years, a number of investigations have evaluated the effect of cannabis use on the risk of presenting ultra-high risk for psychosis (UHR) status as well as its influences on transition rate, suggesting a dose-dependent interactio…
View article: S131. PERCEPTUAL ABNORMALITIES AND RELIGIOSITY IN ULTRA HIGH-RISK FOR PSYCHOSIS (UHR) INDIVIDUALS IN A LATIN AMERICAN POPULATIONAL SAMPLE RESULTS FROM THE SAO PAULO SSAPP COHORT
S131. PERCEPTUAL ABNORMALITIES AND RELIGIOSITY IN ULTRA HIGH-RISK FOR PSYCHOSIS (UHR) INDIVIDUALS IN A LATIN AMERICAN POPULATIONAL SAMPLE RESULTS FROM THE SAO PAULO SSAPP COHORT Open
In the last decades, the ultra-high risk for psychosis (UHR) status has been studied to prevent people from developing full-blown psychosis. To better understand this condition, and to better predict conversion, the relationship between UH…
View article: Increased platelet glycogen sysnthase kinase 3beta in first-episode psychosis
Increased platelet glycogen sysnthase kinase 3beta in first-episode psychosis Open
View article: Poverty, low education, and the expression of psychotic-like experiences in the general population of São Paulo, Brazil
Poverty, low education, and the expression of psychotic-like experiences in the general population of São Paulo, Brazil Open
View article: SA61. Association Between Childhood Adversity and Ultra-High Risk for Psychosis Status in a Populational Sample of Sao Paulo, Brazil
SA61. Association Between Childhood Adversity and Ultra-High Risk for Psychosis Status in a Populational Sample of Sao Paulo, Brazil Open
Background: The relationship between childhood adversity and psychosis is now well established, and research has been broadened to the ultra-high risk for psychosis (UHR) phase. Some studies showed positive findings regarding this link, bu…
View article: Epistasis between COMT Val158Met and DRD3 Ser9Gly polymorphisms and cognitive function in schizophrenia: genetic influence on dopamine transmission
Epistasis between COMT Val158Met and DRD3 Ser9Gly polymorphisms and cognitive function in schizophrenia: genetic influence on dopamine transmission Open
Combined genetic polymorphisms related to dopamine neurotransmission might influence executive function in schizophrenia. Looking at the effects of multiple genes on a single disease trait (epistasis) provides a comprehensive and more reli…
View article: A randomized clinical trial of home-based telepsychiatric outpatient care via videoconferencing: design, methodology, and implementation
A randomized clinical trial of home-based telepsychiatric outpatient care via videoconferencing: design, methodology, and implementation Open
Background Healthcare providers are continuously challenged to find innovative, cost-effective alternatives and to scale up existent services to meet the growing demand upon mental health care delivery. Due to continuous advances in techno…