Mary E. Duffy
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View article: The descent of agamemnon and the disquietude of job: The death of agency as the spur of suicide.
The descent of agamemnon and the disquietude of job: The death of agency as the spur of suicide. Open
We propose that a state of psychological predeath precedes death by suicide, and that this phenomenon results from the undermining of subjectively experienced contingency and thus of agency (i.e., the death of agency). A consequence of the…
Evaluation of Managing Cancer and Living Meaningfully (CALM) in people with advanced non-small cell lung cancer treated with immunotherapies or targeted therapies: protocol for a single-arm, mixed-methods pilot study Open
Introduction People with advanced non-small cell lung cancer (NSCLC) treated with immunotherapies (IT) or targeted therapies (TT) may have improved outcomes in a subset of people who respond, raising unique psychological concerns requiring…
Patterns of care for people with small cell lung cancer in Victoria, 2011–19: a retrospective, population‐based registry data study Open
Objectives To report stage‐specific patterns of treatment and the influence of management and treatment type on survival rates for people newly diagnosed with small cell lung cancer (SCLC). Design Cross‐sectional patterns of care study; an…
Supplementary Data Tables 1-3 from Phenotype-Based Screens with Conformation-Specific Inhibitors Reveal p38 Gamma and Delta as Targets for HCC Polypharmacology Open
Supplemental Table 1 shows RNA-seq signature genes. Supplementary Table 2 shows mass spectrometry profiling data for AD80 in HUH7. Supplementary Table 3 shows in vitro profiling data on compounds.
Supplementary Synthetic Methods from Phenotype-Based Screens with Conformation-Specific Inhibitors Reveal p38 Gamma and Delta as Targets for HCC Polypharmacology Open
Supplemental Synthetic Methods
Supplementary Data Tables 1-3 from Phenotype-Based Screens with Conformation-Specific Inhibitors Reveal p38 Gamma and Delta as Targets for HCC Polypharmacology Open
Supplemental Table 1 shows RNA-seq signature genes. Supplementary Table 2 shows mass spectrometry profiling data for AD80 in HUH7. Supplementary Table 3 shows in vitro profiling data on compounds.
Supplementary Synthetic Methods from Phenotype-Based Screens with Conformation-Specific Inhibitors Reveal p38 Gamma and Delta as Targets for HCC Polypharmacology Open
Supplemental Synthetic Methods
Data from Phenotype-Based Screens with Conformation-Specific Inhibitors Reveal p38 Gamma and Delta as Targets for HCC Polypharmacology Open
The approved kinase inhibitors for hepatocellular carcinoma (HCC) are not matched to specific mutations within tumors. This has presented a daunting challenge; without a clear target or mechanism, no straightforward path has existed to gui…
Supplementary Data Figures 1-7 from Phenotype-Based Screens with Conformation-Specific Inhibitors Reveal p38 Gamma and Delta as Targets for HCC Polypharmacology Open
Supplementary Data Figures 1 shows PK data on AD80. Supplementary Data Figure 2 shows PCA analysis. Supplementary Data Figure 3 shows Gene Set Enrichment of HUH7 cells in response to AD80 and sorafenib. Supplementary Data Figure 4 shows we…
Supplementary Data Figures 1-7 from Phenotype-Based Screens with Conformation-Specific Inhibitors Reveal p38 Gamma and Delta as Targets for HCC Polypharmacology Open
Supplementary Data Figures 1 shows PK data on AD80. Supplementary Data Figure 2 shows PCA analysis. Supplementary Data Figure 3 shows Gene Set Enrichment of HUH7 cells in response to AD80 and sorafenib. Supplementary Data Figure 4 shows we…
Data from Phenotype-Based Screens with Conformation-Specific Inhibitors Reveal p38 Gamma and Delta as Targets for HCC Polypharmacology Open
The approved kinase inhibitors for hepatocellular carcinoma (HCC) are not matched to specific mutations within tumors. This has presented a daunting challenge; without a clear target or mechanism, no straightforward path has existed to gui…
Thinking too much: Rumination as a catalyst of the real-time associations between affective states and suicidal ideation. Open
Affective states and rumination may each confer risk for suicidal ideation in the short term, and rumination may serve as a catalyst of the link between affective states and suicidal ideation when examined concurrently. Clinical implicatio…
View article: Development of an Australia and New Zealand Lung Cancer Clinical Quality Registry: a protocol paper
Development of an Australia and New Zealand Lung Cancer Clinical Quality Registry: a protocol paper Open
Introduction Lung cancer is the leading cause of cancer mortality, comprising the largest national cancer disease burden in Australia and New Zealand. Regional reports identify substantial evidence-practice gaps, unwarranted variation from…
Reliability and validity of a transdiagnostic measure of reward valuation effort. Open
To identify biobehavioral mechanisms underlying excessive reward consumption, reward valuation-effort (RV-E) assessments should (a) parallel measures in basic science to permit translation from preclinical to clinical studies; (b) quantify…
Suicidal ideation, suicide attempts, and suicide death among Veterans and service members: A comprehensive meta-analysis of risk factors Open
Suicide is the tenth leading cause of death in America. Particularly at risk, Veterans are 1.5 times more likely to die by suicide than non-Veterans, and the suicide rate among service members has risen over the last decade. In the present…
Examination of measurement invariance of the Acquired Capability for Suicide Scale. Open
Capability for suicide is frequently assessed using the Acquired Capability for Suicide Scale (ACSS) or the Acquired Capability for Suicide Scale-Fearlessness About Death (ACSS-FAD); however, the measurement invariance of these self-report…
Measurement and construct validity of the Eating Disorder Examination Questionnaire Short Form in a transgender and gender diverse community sample. Open
This study evaluated the measurement and construct validity of the Eating Disorder Examination Questionnaire Short Form (EDE-QS) in a transgender and gender diverse sample. Participants who self-identified as transgender and gender diverse…
Contested bodies : the locations/dislocations of indigenous Australian women in contemporary health Open
This thesis was scanned from the print manuscript for digital preservation and is copyright the author. Researchers can access this thesis by asking their local university, institution or public library to make a request on their behalf. M…
Functional and Patient-reported Changes in Swallowing and Voice After Combined Chemotherapy and Radiotherapy for Limited Stage Small Cell Lung Cancer Open
Purpose : To describe the nature and impact of dysphagia (difficulty swallowing) and dysphonia (impaired voice) in patients with limited-stage small cell lung cancer (SCLC) before and after chemoradiation. Methods : A prospective cohort st…
Identity problems and suicidal ideation severity among women with bulimic-spectrum pathology. Open
Individuals with bulimia nervosa often experience suicidal ideation. Identity disturbance, or unstable sense of self, has been connected both to eating disorders and to suicidality. This study sought to test whether identity problems were …
View article: Adverse respiratory outcomes following conventional long‐course radiotherapy for non‐small‐cell lung cancer in patients with pre‐existing pulmonary fibrosis: A comparative retrospective study
Adverse respiratory outcomes following conventional long‐course radiotherapy for non‐small‐cell lung cancer in patients with pre‐existing pulmonary fibrosis: A comparative retrospective study Open
Introduction There is some evidence to suggest that patients with underlying pulmonary fibrosis (PF) have increased risk of adverse respiratory and survival outcomes, when treated with conventional, long‐course radiotherapy (RT) for non‐sm…
Scope of Practice, Role Legitimacy, and Role Potential for Cancer Care Coordinators Open
The findings underline the need when establishing and reviewing CCC roles for explicit attention to be given to the reporting, integration, structural, and collegiate support for the role as this will profoundly influence its success.
Psychotic symptoms and suicidal ideation in child and adolescent bipolar I disorder Open
Objectives The purpose of this study was to explore associations between specific types of hallucinations and delusions and suicidal ideation in a sample of children and adolescents with bipolar I disorder. Methods Participants (N = 379) w…
Investigating the reliability of suicide attempt history reporting across five measures: A study of US military service members at risk of suicide Open
Objective Utilizing a sample of military service members at risk of suicide, this study aimed to: (a) identify patterns of suicide attempt (SA) history reporting across five measures and (b) evaluate whether consistent SA reporters (i.e., …
Age, period, and cohort trends in mood disorder indicators and suicide-related outcomes in a nationally representative dataset, 2005–2017. Open
Drawing from the National Survey on Drug Use and Health (NSDUH; N = 611,880), a nationally representative survey of U.S. adolescents and adults, we assess age, period, and cohort trends in mood disorders and suicide-related outcomes since …
Problematic Alcohol Use and Suicidal Ideation Among Firefighters: A Multi-Study Investigation of the Explanatory Roles of Perceived Burdensomeness and Thwarted Belongingness Open
Background: Firefighters are at increased risk for both problematic alcohol use and suicidality. Research has found that problematic alcohol use is related to suicidality among this population; however, limited data exist regarding what mi…
Development of a hospital-based patient-reported outcome framework for lung cancer patients: a study protocol Open
This study is not a clinical trial and is therefore not registered in any trial registry. However, it has received human research ethics approval (LNR/16/PMCC/45).