Maryam Hajfathalian
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View article: Bacteriophage purification using CIMmultus monolithic OH-column chromatography for therapeutic purposes
Bacteriophage purification using CIMmultus monolithic OH-column chromatography for therapeutic purposes Open
Bacteriophages, viruses that selectively infect bacteria, are increasingly explored as potential therapies to combat antibiotic-resistant infections. Effective phage purification is vital for therapeutic use, particularly to reduce endotox…
View article: Dosing and Delivery of Bacteriophage Therapy In a Murine Wound Infection Model
Dosing and Delivery of Bacteriophage Therapy In a Murine Wound Infection Model Open
Lytic bacteriophages, viruses that lyse (kill) bacteria, hold great promise for treating infections, including wound infections caused by antimicrobial-resistant Pseudomonas aeruginosa. However, dosing and delivery strategies for phage the…
View article: A review of recent advances in the use of complex metal nanostructures for biomedical applications from diagnosis to treatment
A review of recent advances in the use of complex metal nanostructures for biomedical applications from diagnosis to treatment Open
Complex metal nanostructures represent an exceptional category of materials characterized by distinct morphologies and physicochemical properties. Nanostructures with shape anisotropies, such as nanorods, nanostars, nanocages, and nanopris…
View article: Optimized preparation pipeline for emergency phage therapy against Pseudomonas aeruginosa at Yale University
Optimized preparation pipeline for emergency phage therapy against Pseudomonas aeruginosa at Yale University Open
Bacteriophage therapy is one potential strategy to treat antimicrobial resistant or persistent bacterial infections, and the year 2021 marked the centennial of Felix d’Hérelle’s first publication on the clinical applications of phages. At …
View article: A Biodegradable “One‐For‐All” Nanoparticle for Multimodality Imaging and Enhanced Photothermal Treatment of Breast Cancer
A Biodegradable “One‐For‐All” Nanoparticle for Multimodality Imaging and Enhanced Photothermal Treatment of Breast Cancer Open
Silver sulfide nanoparticles (Ag 2 S‐NP) hold promise for various optical‐based biomedical applications, such as near‐infrared fluorescence (NIRF) imaging, photoacoustics (PA), and photothermal therapy (PTT). However, their NIR absorbance …
View article: A biodegradable “one-for-all” nanoparticle for multimodality imaging and enhanced photothermal treatment of breast cancer
A biodegradable “one-for-all” nanoparticle for multimodality imaging and enhanced photothermal treatment of breast cancer Open
Silver sulfide nanoparticles (Ag 2 S-NP) have been proposed for various optical-based biomedical applications, such as near-infrared fluorescence (NIRF) imaging, photoacoustics (PA) and photothermal therapy (PTT). However, their absorbance…
View article: Rapid assessment of changes in phage bioactivity using dynamic light scattering
Rapid assessment of changes in phage bioactivity using dynamic light scattering Open
Extensive efforts are underway to develop bacteriophages as therapies against antibiotic-resistant bacteria. However, these efforts are confounded by the instability of phage preparations and a lack of suitable tools to assess active phage…
View article: Theranostic gold-in-gold cage nanoparticles enable photothermal ablation and photoacoustic imaging in biofilm-associated infection models
Theranostic gold-in-gold cage nanoparticles enable photothermal ablation and photoacoustic imaging in biofilm-associated infection models Open
Biofilms are structured communities of microbial cells embedded in a self-produced matrix of extracellular polymeric substances. Biofilms are associated with many health issues in humans, including chronic wound infections and tooth decay.…
View article: Rapid assessment of changes in phage bioactivity using dynamic light scattering
Rapid assessment of changes in phage bioactivity using dynamic light scattering Open
Extensive efforts are underway to develop bacteriophages as therapies against antibiotic-resistant bacteria. However, these efforts are confounded by the instability of phage preparations and a lack of suitable tools to assess active phage…
View article: Theranostic gold in a gold cage nanoparticle for photothermal ablation and photoacoustic imaging of skin and oral infections
Theranostic gold in a gold cage nanoparticle for photothermal ablation and photoacoustic imaging of skin and oral infections Open
Biofilms are structured communities of microbial cells embedded in a self-produced matrix of extracellular polymeric substances. Biofilms are associated with many health issues in humans, including chronic wound infections and tooth decay.…
View article: Nisin and Nisin Probiotic Disrupt Oral Pathogenic Biofilms and Restore Their Microbiome Composition towards Healthy Control Levels in a Peri-Implantitis Setting
Nisin and Nisin Probiotic Disrupt Oral Pathogenic Biofilms and Restore Their Microbiome Composition towards Healthy Control Levels in a Peri-Implantitis Setting Open
Peri-implantitis is characterized by chronic inflammation of the peri-implant supporting tissues that progressively and irreversibly leads to bone loss and, consequently, implant loss. Similar to periodontal disease, oral dysbiosis is thou…
View article: Filamentous bacteriophage delays healing of Pseudomonas-infected wounds
Filamentous bacteriophage delays healing of Pseudomonas-infected wounds Open
View article: Precision targeting of bacterial pathogen via bi-functional nanozyme activated by biofilm microenvironment
Precision targeting of bacterial pathogen via bi-functional nanozyme activated by biofilm microenvironment Open
View article: Dextran-Coated Cerium Oxide Nanoparticles: A Computed Tomography Contrast Agent for Imaging the Gastrointestinal Tract and Inflammatory Bowel Disease
Dextran-Coated Cerium Oxide Nanoparticles: A Computed Tomography Contrast Agent for Imaging the Gastrointestinal Tract and Inflammatory Bowel Disease Open
Computed tomography (CT) is an X-ray-based medical imaging technique commonly used for noninvasive gastrointestinal tract (GIT) imaging. Iodine- and barium-based CT contrast agents are used in the clinic for GIT imaging; however, inflammat…
View article: Effect of Gold Nanoparticle Size on Their Properties as Contrast Agents for Computed Tomography
Effect of Gold Nanoparticle Size on Their Properties as Contrast Agents for Computed Tomography Open
View article: Synthesis and Properties of Au Hydride
Synthesis and Properties of Au Hydride Open
The generation of chemical species from gases, noble metals and light interacting with localized surface plasmons represents a new paradigm for achieving low energy sustainable reaction pathways. Here, we demonstrate that the dissociation …
View article: Substrate-Based Noble-Metal Nanomaterials: Shape Engineering and Applications
Substrate-Based Noble-Metal Nanomaterials: Shape Engineering and Applications Open
Nanostructures have potential for use in state-of-the-art applications such as sensing, imaging, therapeutics, drug delivery, and electronics. The ability to fabricate and engineer these nanoscale materials is essential for the continued d…
View article: Gold silver alloy nanoparticles (GSAN): an imaging probe for breast cancer screening with dual-energy mammography or computed tomography
Gold silver alloy nanoparticles (GSAN): an imaging probe for breast cancer screening with dual-energy mammography or computed tomography Open
Earlier detection of breast cancer reduces mortality from this disease. As a result, the development of better screening techniques is a topic of intense interest. Contrast-enhanced dual-energy mammography (DEM) is a novel technique that h…