Explanipedia

Modulation of Auditory Cortex Activity in Salicylate‐Induced Tinnitus Rats via Deep Brain Stimulation of the Inferior Colliculus Open

Zeinab Akbarnejad, Kasra Bagherian, Seyed Ali Noorbakhsh, Ali Fathi Jouzdani, Saeid Mahmoudian , et al. · 2025

Background Tinnitus, a self‐reported perceptual disorder, is currently believed to arise from maladaptive plasticity due to reduced sensory input. While deep brain stimulation (DBS) has shown promise in alleviating tinnitus‐related behavio…

Ferroptosis as a therapeutic target in glioblastoma: Mechanisms and emerging strategies Open

Sohail Mashayekhi, Hossein Majedi, Ahmad Reza Dehpour, Samaneh Dehghan, Maryam Jafarian , et al. · 2025

The role of high-density lipoprotein and Vitamin D in exercise-induced neuroprotection in epileptic rats Open

Gelareh Vahhabzadeh, Asal Salimi, Taha Ghantabpour, Ali Mohammadkhanizadeh, Maryam Jafarian , et al. · 2025

Previous studies have reported the neuroprotective effects of exercise in epilepsy. Hence, this study aimed to investigate the potential mechanisms underlying these neuroprotective effects by examining changes in high-density lipoprotein (…

The Modulatory Effect of Exercise on the Endocannabinoid Signaling Pathway in the Epileptic Rats Open

Asal Salimi, Taha Ghantabpour, Homa Rasoolijazi, Fahime Zavvari, Maryam Jafarian , et al. · 2024

Background: Regular moderate exercise and endogenous cannabinoid activity have independently been shown to alleviate seizure (SE) attacks. Objectives: This study aimed to investigate the effect of physical activity on the expression levels…

Pre-adolescence repeat exposure to sub-anesthetic doses of ketamine induces long-lasting behaviors and cognition impairment in male and female rat adults Open

Amir Barzegar Behrooz, Mahdieh Nasiri, Soheila Adeli, Maryam Jafarian, Seyed Khalil Pestehei , et al. · 2024

In pre-adolescence, repeated anesthesia may be required for therapeutic interventions. Adult cognitive and neurobehavioral problems may result from preadolescent exposure to anesthetics. This study examined the long-term morphological and …

Hydrogel-encapsulated extracellular vesicles for the regeneration of spinal cord injury Open

Yasaman Nazerian, Amirhossein Nazerian, Fereshteh Mohamadi-Jahani, Parastoo Sodeifi, Maryam Jafarian , et al. · 2023

Spinal cord injury (SCI) is a critical neurological condition that may impair motor, sensory, and autonomous functions. At the cellular level, inflammation, impairment of axonal regeneration, and neuronal death are responsible for SCI-rela…

Investigating the Effect of Neuro-Motor Rehabilitation on Myelin Regeneration after Spinal Cord Injury Model in Rats Open

Faezeh Yaghoubi, Bita Vazir, Saeed Hesaraki, Ameneh Omidi, Mahmoudreza Hadjighassem , et al. · 2023

Investigating the Effect of Neuro-Motor Rehabilitation on Myelin Regeneration after Spinal Cord Injury Model in Rats

THE EFFECT OF GABAERGIC NEUROTRANSMISSION ON THE SEIZURE-RELATED ACTIVITY OF THE LATERODORSAL THALAMIC NUCLEI AND THE SOMATOSENSORY CORTEX IN AGENETIC MODEL OF ABSENCE EPILEPSY Open

Maryam Jafarian · 2023

Clinical Correlation of Altered Molecular Signatures in Epileptic Human Hippocampus and Amygdala Open

Sayed Mostafa Modarres Mousavi, Fatemeh Alipour, Farshid Noorbakhsh, Maryam Jafarian, Masoud Ghadipasha , et al. · 2023

Widespread alterations in the expression of various genes could contribute to the pathogenesis of epilepsy. The expression levels of various genes, including major inhibitory and excitatory receptors, ion channels, cell type-specific marke…

Biomarkers in Brain Traumatic Injury Open

Hoorie Sadat Sabet, Fereshte Sadat Sabet, Karim Shojaei, Faezeh Yaghoubi, Maryam Jafarian · 2022

Department of Biological Sciences Engineering, Faculty of Modern Sciences and Arts, University of Tehran, Tehran, Iran , [email protected]

The Anticonvulsant Effect of the Ketogenic Diet in the Treatment of Epilepsy Open

Faezeh yaghoubi, Maryam Jafarian, Ali Gorji · 2020

Introduction:Epilepsy has been considered a chronic brain disorder, which affects almos t1% of the world population.Among this population, about a third of epilepsy patients are considered as the drug-resis tant group who are not responsiv…

Experimental Models of Absence Epilepsy Open

Maryam Jafarian, Mohammad Esmaeil Alipour, Fariba Karimzadeh · 2020

Introduction: Absence epilepsy is a brief non-convulsive seizure associated with sudden abruptness in consciousness. Because of the unpredictable occurrence of absence seizures and the ethical issues of human investigation on the pathogene…

Experimental Models of Absence Epilepsy: A Review Article Open

Maryam Jafarian, Mohammadesmaeil Alipour, Fariba Karimzadeh · 2019

Introduction: Absence epilepsy is a brief non-convulsive seizure associated with sudden abruptness in consciousness.Because of the unpredictable occurrence of absence seizures and the ethical issues of human investigation on the pathogenes…

Generation of motor neurons from human amygdala-derived neural stem-like cells. Open

Sepideh Ghasemi, Hadi Aligholi, Pir Hossein Koulivand, Maryam Jafarian, Hassan Hosseini Ravandi , et al. · 2018

Isolation and culture of these cells enable us to improve our knowledge of the role of the amygdala in some neurological and psychological disorders and provide a novel source for therapeutic cell transplantation.

Modulatory Effect of Glial-Derived Growth Factor on Addiction Open

Maryam Jafarian, Mohammadesmaeil Alipour · 2016

Introduction: Glial-derived growth factor (GDNF) is an important secretory protein that plays a crutial role in the growth and development of the central and peripheral nervous systems, especially the survival of dopaminergic adult neurons…

Phylogenetic Study of GABAA Receptors in Human and Rat Species: Evaluation of Family Relationship Open

Zahrasadat Hashemi, Arezou Eshaghabadi, Fatemeh Alipour, Maryam Jafarian, Mostafa Modarres Mousavi · 2016

Introduction: An effort to establish phylogenetic values for the major gamma-Aminobutyric acid A (GABAA) receptor subunit mRNAs α, β, γ, δ, ε, θ, π could be improved our knowledge on their classification and function. In addition, the simi…

The Effects of Backpack Weight on the Static and Dynamic Balances of Female Students Open

Saeid Bahiraei, Maryam Jafarian, Ebrahim Mohammad Ali Nasab · 2015

The main aim of this study was to investigate the effects of carrying backpack on the balance of female students aged 9-11 years. In the present study, 30 students (mean age of 15.02±2.07 years, height of 140±8 cm, and weight of 41.51±15.2…

The Effects of Backpack Weight on the Static and Dynamic Balances of Female Students Open

Saeid Bahiraei, Maryam Jafarian, Ebrahim Mohammad Ali Nasab · 2015

The main aim of this study was to investigate the effects of carrying backpack on the balance of female students aged 9-11 years.In the present study, 30 students (mean age of 15.02±2.07years, height of 140±8 cm, and weight of 41.51±15.26k…

Role of Laterodorsal Thalamic Nucleus during Absence Seizure Attacks Open

Ahmad Ali Lotfinia, Maryam Jafarian, Mostafa Modarres Mousavi, Hassan Hosseini Ravandi, Fariba Karimzadeh · 2015

Introduction: A typical absence epilepsy is a type of nonconvulsive and generalized epilepsy. The main feature of these attacks is a sudden brief impairment of consciousness. The disturbances in thalamocortical loop play an important role …

The Effect of Carbamazepine on Neuronal Damage in Pentylentetrazole Model of Seizure Open

Mahya Zamani Esmati, Hanieh Malakzadeh, Hanieh Jenab Esfahani, Arezou Eshaghabadi, Sedigheh Ghasemi , et al. · 2015

Introduction: Epilepsy is the most common disorder of the central nerves system. Studies showed that carbamazepine has anti-epileptic effects. However, there is no evidence whether carbamazepine protect seizure-induced neuronal injury. In …

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