Maryam Karimi
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View article: Deep Learning Bridges Histology and Transcriptomics to Predict Molecular Subtypes and Outcomes in Muscle-Invasive Bladder Cancer
Deep Learning Bridges Histology and Transcriptomics to Predict Molecular Subtypes and Outcomes in Muscle-Invasive Bladder Cancer Open
Muscle-Invasive Bladder Cancer (MIBC) is a heterogeneous disease with distinct molecular subtypes influencing prognosis and therapeutic response. However, molecular profiling through RNA sequencing remains costly, time-consuming and compli…
View article: Identifying health conditions associated with an increased risk of pancreatic ductal adenocarcinoma at medium term in nationwide electronic health records of primary care physicians
Identifying health conditions associated with an increased risk of pancreatic ductal adenocarcinoma at medium term in nationwide electronic health records of primary care physicians Open
Background Pancreatic ductal adenocarcinoma (PDAC) presents an urgent challenge that necessitates improved early risk identification. We investigated the association between predictors of PDAC present at least two years before diagnosis an…
View article: Characteristics, management and survival outcomes in patients with muscle-invasive bladder cancer at high risk of recurrence in France: a subgroup analysis from the coblance cohort
Characteristics, management and survival outcomes in patients with muscle-invasive bladder cancer at high risk of recurrence in France: a subgroup analysis from the coblance cohort Open
View article: Incidence of Bladder Cancer, Healthcare Pathways, and Economic Burden: A Real-World Observational Study From the French National Healthcare System Database
Incidence of Bladder Cancer, Healthcare Pathways, and Economic Burden: A Real-World Observational Study From the French National Healthcare System Database Open
View article: Stability Selection and Consensus Clustering in <i>R</i>: The <i>R</i> Package <b>sharp</b>
Stability Selection and Consensus Clustering in <i>R</i>: The <i>R</i> Package <b>sharp</b> Open
The R package sharp (Stability-enHanced Approaches using Resampling Procedures) provides an integrated framework for stability-enhanced variable selection, graphical modeling and clustering. In stability selection, a feature selection algo…
View article: Surgery for Severe Endometriosis and ART Outcome and Effect of Time Interval Between Surgery and FET
Surgery for Severe Endometriosis and ART Outcome and Effect of Time Interval Between Surgery and FET Open
Background and Aims: To evaluate fertility outcomes in infertile women with severe endometriosis who underwent Frozen embryo transfer (FET) after laparoscopic surgery and assess the optimal time interval between laparoscopy and FET.Materia…
View article: Evaluation of Human Papillomavirus in the Semen of Infertile Men and Its Relationship with Semen Quality
Evaluation of Human Papillomavirus in the Semen of Infertile Men and Its Relationship with Semen Quality Open
Background: The prevalence of human papillomavirus (HPV) infection in infertile men is significantly higher than that in the general population. Nevertheless, it is unclear whether the presence of HPV in semen samples is related to reduced…
View article: Insights adjusting for non-adherence in randomized clinical trials: a reanalysis of an adjuvant trial of tamoxifen duration in early breast cancer
Insights adjusting for non-adherence in randomized clinical trials: a reanalysis of an adjuvant trial of tamoxifen duration in early breast cancer Open
Background Several randomized clinical trials provide evidence of the survival benefit of extended adjuvant tamoxifen in women with estrogen receptor (ER)-positive early breast cancer (BC). However, non-adherence may lead to underestimate …
View article: A Case-Only Genome-Wide Interaction Study of Smoking and Bladder Cancer Risk: Results from the COBLAnCE Cohort
A Case-Only Genome-Wide Interaction Study of Smoking and Bladder Cancer Risk: Results from the COBLAnCE Cohort Open
Bladder cancer (BC) is the 6th most common cancer worldwide, with tobacco smoking considered as its main risk factor. Accumulating evidence has found associations between genetic variants and the risk of BC. Candidate gene-environment inte…
View article: Association of Molecular Profiles and Mutational Status With Distinct Histological Lung Adenocarcinoma Subtypes. An Analysis of the LACE-Bio Data
Association of Molecular Profiles and Mutational Status With Distinct Histological Lung Adenocarcinoma Subtypes. An Analysis of the LACE-Bio Data Open
View article: Prevalence of Human Papillomavirus in Iranian infertile men and its association with semen quality
Prevalence of Human Papillomavirus in Iranian infertile men and its association with semen quality Open
Background: The present article aims to elucidate the prevalence of Human Papillomavirus (HPV) infection and possible association between HPV infection and semen parameters in infertile Iranian men. Materials and methods: This cross-sectio…
View article: Comprehensive Genome Profiling in Patients With Metastatic Non–Small Cell Lung Cancer: The Precision Medicine Phase II Randomized SAFIR02-Lung/IFCT 1301 Trial
Comprehensive Genome Profiling in Patients With Metastatic Non–Small Cell Lung Cancer: The Precision Medicine Phase II Randomized SAFIR02-Lung/IFCT 1301 Trial Open
Purpose: Targeted therapies (TT) and immune checkpoint blockers (ICB) have revolutionized the approach to non–small cell lung cancer (NSCLC) treatment in the era of precision medicine. Their impact as switch maintenance therapy based on mo…
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View article: Near-Infrared Fluorescence Axillary Reverse Mapping (ARM) Procedure in Invasive Breast Cancer: Relationship between Fluorescence Signal in ARM Lymph Nodes and Clinical Outcomes
Near-Infrared Fluorescence Axillary Reverse Mapping (ARM) Procedure in Invasive Breast Cancer: Relationship between Fluorescence Signal in ARM Lymph Nodes and Clinical Outcomes Open
The near-infrared (NIR) fluorescence axillary reverse mapping (ARM) procedure is a promising tool to identify and preserve arm lymphatic drainage during axillary lymph node dissection (ALND). The ARMONIC clinical trial was conducted to val…
View article: Epigenetic mechanisms of lung carcinogenesis involve differentially methylated CpG sites beyond those associated with smoking
Epigenetic mechanisms of lung carcinogenesis involve differentially methylated CpG sites beyond those associated with smoking Open
Smoking-related epigenetic changes have been linked to lung cancer, but the contribution of epigenetic alterations unrelated to smoking remains unclear. We sought for a sparse set of CpG sites predicting lung cancer and explored the role o…
View article: Molecular profiling of non-small-cell lung cancer patients with or without brain metastases included in the randomized SAFIR02-LUNG trial and association with intracranial outcome
Molecular profiling of non-small-cell lung cancer patients with or without brain metastases included in the randomized SAFIR02-LUNG trial and association with intracranial outcome Open
View article: Near-infrared fluorescence axillary reverse mapping (ARM) procedure in invasive breast cancer: relationship between fluorescence signal in ARM lymph nodes and clinical outcomes
Near-infrared fluorescence axillary reverse mapping (ARM) procedure in invasive breast cancer: relationship between fluorescence signal in ARM lymph nodes and clinical outcomes Open
Introduction: Near-infrared (NIR) fluorescence axillary reverse mapping (ARM) procedure is a promising tool to identify and preserve arm lymphatic drainage during axillary lymph node dissection (ALND). The ARMONIC clinical trial was conduc…
View article: The Effect of high intensity interval training on serum levels of Osteopontin and insulin resistance index in sedentary overweight and obese women
The Effect of high intensity interval training on serum levels of Osteopontin and insulin resistance index in sedentary overweight and obese women Open
Purpose: Osteopontin is a novel adipose tissue derived cytokine correlating with obesity and its related metabolic diseases such as insulin resistance and type II diabetes. The purpose of this study was to investigate effect of high intens…
View article: Multicenter evaluation of breast cancer patients’ satisfaction and experience with oncology telemedicine visits during the COVID-19 pandemic
Multicenter evaluation of breast cancer patients’ satisfaction and experience with oncology telemedicine visits during the COVID-19 pandemic Open
View article: The Effect of Emotional Intelligence Components on Maternal Parenting Stress
The Effect of Emotional Intelligence Components on Maternal Parenting Stress Open
The present study investigated the effectiveness of emotional intelligence training on parenting stress of mothers of children with physical disabilities. Among the mothers who had high stress scores and minimum secondary education, they w…
View article: Considering the Main Center for Treatment and Counseling of Cancer Patients
Considering the Main Center for Treatment and Counseling of Cancer Patients Open
In this project, considering that is the main center for treatment and counseling of cancer patients, the inpatient wards of men and women and the oncology clinic of this hospital were considered as the research environment. Researchers us…
View article: A Review of Emotions Makes up The Bulk of Life
A Review of Emotions Makes up The Bulk of Life Open
The direct and indirect presence of emotions can be seen in reasoning and rationality. Ignorance of emotions, their lack of management and carelessness in expressing them can have huge costs for human beings. New research shows that lack o…
View article: Prognostic and predictive effect of KRAS gene copy number and mutation status in early stage non-small cell lung cancer patients
Prognostic and predictive effect of KRAS gene copy number and mutation status in early stage non-small cell lung cancer patients Open
A small prognostic effect of KRAS mutation was identified for LCSS, and a trend towards worse LCSS, DFS and OS was noted for KRAS MUT + Gain. A potential predictive effect of concomitant KRAS mutation and copy number g…
View article: Effects of Eight Weeks of Core Stability Training on Serum level of Progranulin and Tumor Necrosis Factor Alpha in Women with Multiple Sclerosis
Effects of Eight Weeks of Core Stability Training on Serum level of Progranulin and Tumor Necrosis Factor Alpha in Women with Multiple Sclerosis Open
Effects of Eight Weeks of Core Stability Training on Serum level of Progranulin and Tumor Necrosis Factor Alpha in Women with Multiple Sclerosis
View article: Impact of ejaculatory abstinence period and semen characteristic on the reproductive outcomes after intracytoplasmic sperm injection
Impact of ejaculatory abstinence period and semen characteristic on the reproductive outcomes after intracytoplasmic sperm injection Open
The abstinence period before ICSI can influence the semen volume and total sperm count, and possibly fertilization. Although the sperm with the highest quality are selected for ICSI, the percentages of progressively motile and morphologica…
View article: Education, biological ageing, all-cause and cause-specific mortality and morbidity: UK biobank cohort study
Education, biological ageing, all-cause and cause-specific mortality and morbidity: UK biobank cohort study Open
View article: The Troponin-I Release in Patients with Left-Sided Early-Stage Breast Cancer Undergoing Adjuvant Whole Breast Radiotherapy: An Iranian Experience
The Troponin-I Release in Patients with Left-Sided Early-Stage Breast Cancer Undergoing Adjuvant Whole Breast Radiotherapy: An Iranian Experience Open
Background: Breast cancer is the most frequent cancer among women. In line with the survival improvement of patients with cancer, the issue of treatment-induced toxicities becomes more important. Objectives: This study aimed at evaluating …
View article: 1273P Durvalumab (D) compared to maintenance chemotherapy (SoC) in patients (pts) with metastatic non-small cell lung cancer (NSCLC): Results from the randomized SAFIR02 LUNG-IMMUNO trial
1273P Durvalumab (D) compared to maintenance chemotherapy (SoC) in patients (pts) with metastatic non-small cell lung cancer (NSCLC): Results from the randomized SAFIR02 LUNG-IMMUNO trial Open
View article: 1710P International multicentric evaluation of breast cancer patients’ satisfaction and experience with oncology telemedicine visits (TV) during the COVID-19 outbreak
1710P International multicentric evaluation of breast cancer patients’ satisfaction and experience with oncology telemedicine visits (TV) during the COVID-19 outbreak Open
View article: Correction to: Does timing in ICSI cycle affect oocyte quality and reproductive outcomes? A prospective study
Correction to: Does timing in ICSI cycle affect oocyte quality and reproductive outcomes? A prospective study Open