Maryam Zarkesh
YOU?
Author Swipe
View article: Within-family analysis of PRS313: insights into breast cancer risk prediction
Within-family analysis of PRS313: insights into breast cancer risk prediction Open
View article: Metabolomics fingerprinting of thyroid malignancies: a GC/MS-based approach for subtype classification and biomarker discovery
Metabolomics fingerprinting of thyroid malignancies: a GC/MS-based approach for subtype classification and biomarker discovery Open
Background Thyroid cancer encompasses distinct histological subtypes, each potentially associated with unique metabolic characteristics. However, the comprehensive metabolic reprogramming underlying these malignancies remains insufficientl…
View article: Plasma Fatty Acid Profiles Modulate <scp>PPARγ</scp> Expression in Adipose Tissue: A Lipidomic Insight Into Obesity‐Related Metabolic Dysregulation
Plasma Fatty Acid Profiles Modulate <span>PPARγ</span> Expression in Adipose Tissue: A Lipidomic Insight Into Obesity‐Related Metabolic Dysregulation Open
Aim This study aimed to investigate the relationship between plasma fatty acids (FAs), FA‐derived factors and PPARγ expression in visceral and subcutaneous adipose tissues (VAT and SAT) of obese and nonobese adults. Methods This cross‐sect…
View article: The association of PTEN/PI3K/Akt pathway gene expression with insulin indices in adipose tissues of non-diabetic female adults: a cross-sectional study
The association of PTEN/PI3K/Akt pathway gene expression with insulin indices in adipose tissues of non-diabetic female adults: a cross-sectional study Open
View article: Genetic and environmental contribution to phenotypic resemblance between Iranian couples: Tehran Cardiometabolic and Genetic Study (TCGS)
Genetic and environmental contribution to phenotypic resemblance between Iranian couples: Tehran Cardiometabolic and Genetic Study (TCGS) Open
View article: Tracking the correlation of mineral intakes among family pairs over nine years: a longitudinal study
Tracking the correlation of mineral intakes among family pairs over nine years: a longitudinal study Open
Our study revealed a decreasing trend in correlation or regression towards the mean over time for most minerals in family pairs.
View article: The relationship between dietary branched-chain and aromatic amino acids with the regulation of leptin and FTO genes in adipose tissue of patients undergoing abdominal surgery
The relationship between dietary branched-chain and aromatic amino acids with the regulation of leptin and FTO genes in adipose tissue of patients undergoing abdominal surgery Open
Recent studies have suggested that the interaction between diet and an individual's genetic predisposition can determine the likelihood of obesity and various metabolic disorders. The current study aimed to examine the association of dieta…
View article: Familial resemblance in dietary intake among singletons, twins, and spouses: a meta-analysis of family-based observations
Familial resemblance in dietary intake among singletons, twins, and spouses: a meta-analysis of family-based observations Open
View article: Long-term nitrate administration modulates sialin gene expression in the main tissues of male Wistar rats with type 2 diabetes
Long-term nitrate administration modulates sialin gene expression in the main tissues of male Wistar rats with type 2 diabetes Open
The increased sialin gene expression in the main tissues of diabetic rats is associated with decreased nitrate and nitrite levels, suggesting a counterregulatory response for reduced nitric oxide (NO) bioavailability. In this study, we hyp…
View article: Expression of TSPAN1 and its link to thyroid nodules: one step forward on the path to thyroid tumorigenesis biomarkers
Expression of TSPAN1 and its link to thyroid nodules: one step forward on the path to thyroid tumorigenesis biomarkers Open
View article: Thyroid Function in the Time of COVID-19: A Systematic Review of Disease Progression and Vaccination Effect
Thyroid Function in the Time of COVID-19: A Systematic Review of Disease Progression and Vaccination Effect Open
Objectives: This systematic review sought to address three key questions: (1) what differences in abnormal thyroid function test results are observed between COVID-19 patients and healthy individuals? (2) How does the severity of COVID-19 …
View article: The association of dietary insulinemic indices with PI3K, PTEN, and Akt gene expressions in visceral and subcutaneous adipose tissues among individuals undergoing abdominal surgery
The association of dietary insulinemic indices with PI3K, PTEN, and Akt gene expressions in visceral and subcutaneous adipose tissues among individuals undergoing abdominal surgery Open
Background/objective The current study investigates the association between dietary insulinemic indices and Akt, PTEN, and PI3K gene expressions in visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) among individuals under…
View article: The effect of family structure on the still-missing heritability and genomic prediction accuracy of type 2 diabetes
The effect of family structure on the still-missing heritability and genomic prediction accuracy of type 2 diabetes Open
View article: Examining the clinical and genetic spectrum of maturity-onset diabetes of the young (MODY) in Iran
Examining the clinical and genetic spectrum of maturity-onset diabetes of the young (MODY) in Iran Open
View article: The effect of family structure on the still-missing heritability and genomic prediction accuracy of type 2 diabetes
The effect of family structure on the still-missing heritability and genomic prediction accuracy of type 2 diabetes Open
This study aims to assess the effect of familial structures on the still-missing heritability estimate and prediction accuracy of Type 2 Diabetes (T2D) using pedigree estimated risk values (ERV) and genomic ERV. We used 11,818 individuals …
View article: Effect of long-term inorganic nitrate administration on myocardial ischemia-reperfusion injury in ovariectomized rats
Effect of long-term inorganic nitrate administration on myocardial ischemia-reperfusion injury in ovariectomized rats Open
Introduction: Menopause is associated with reduced nitric oxide (NO) bioavailability and lower tolerance against myocardial ischemia-reperfusion (IR) injury. This study investigated whether long-term nitrate administration provides resista…
View article: The Tehran longitudinal family-based cardiometabolic cohort study sheds new light on dyslipidemia transmission patterns
The Tehran longitudinal family-based cardiometabolic cohort study sheds new light on dyslipidemia transmission patterns Open
View article: From Genes to Diagnosis: Examining the Clinical and Genetic Spectrum of Maturity-Onset Diabetes of the Young (MODY) in TCGS
From Genes to Diagnosis: Examining the Clinical and Genetic Spectrum of Maturity-Onset Diabetes of the Young (MODY) in TCGS Open
Maturity-onset diabetes of the young (MODY) is an uncommon monogenic type of diabetes mellitus. Detecting genetic biomarkers for MODY is a necessity for precise diagnosis and treatment. The majority of MODY genetic predisposition has been …
View article: Parent–child correlation in energy and macronutrient intakes: A meta‐analysis and systematic review
Parent–child correlation in energy and macronutrient intakes: A meta‐analysis and systematic review Open
In the current study, we aimed to review the evidence from twin and family‐based studies that have assessed the familial similarity in intakes of energy and macronutrients among various parent–child pairs. The online literature databases, …
View article: Insulin resistance-related circulating predictive markers in the metabolic syndrome: a systematic review in the Iranian population
Insulin resistance-related circulating predictive markers in the metabolic syndrome: a systematic review in the Iranian population Open
View article: Genetically predicted smoking behaviors on Graves’ disease: A two-sample mendelian randomization
Genetically predicted smoking behaviors on Graves’ disease: A two-sample mendelian randomization Open
Background/Aim The potential link between smoking and the susceptibility to Graves’ disease (GD) has been scrutinized in observational studies, yielding inconsistent results. We conducted a Mendelian randomization (MR) analysis to ascertai…
View article: RET/PTC rearrangement in papillary thyroid carcinoma arising in malignant struma ovarii with abdominal wall metastasis and cervical thyroid gland: a case report and review of the literature
RET/PTC rearrangement in papillary thyroid carcinoma arising in malignant struma ovarii with abdominal wall metastasis and cervical thyroid gland: a case report and review of the literature Open
Background Struma ovarii refers to rare mature cystic teratomas containing at least 50% of thyroid tissue, and malignant transformation is known to be even rarer. The synchronous development of malignant struma ovarii and cervical thyroid …
View article: Familial resemblance and family-based heritability of nutrients intake in Iranian population: Tehran cardiometabolic genetic study
Familial resemblance and family-based heritability of nutrients intake in Iranian population: Tehran cardiometabolic genetic study Open
View article: Association of baseline and changes in adiponectin, homocysteine, high-sensitivity C-reactive protein, interleukin-6, and interleukin-10 levels and metabolic syndrome incidence: Tehran lipid and glucose study
Association of baseline and changes in adiponectin, homocysteine, high-sensitivity C-reactive protein, interleukin-6, and interleukin-10 levels and metabolic syndrome incidence: Tehran lipid and glucose study Open
After a six-year average follow-up, hs-CRP and IL-6 levels were deemed more reliable predictors of MetS incidence and persistence, respectively.
View article: Genetically predicted 25-Hydroxyvitamin D levels on Hypothyroidism: A two-sample Mendelian Randomization
Genetically predicted 25-Hydroxyvitamin D levels on Hypothyroidism: A two-sample Mendelian Randomization Open
Background Alterations in levels of 25-Hydroxyvitamin D have been associated with the risk of thyroid disease. This study uses Mendelian randomization (MR) to infer the possible causal association of 25-Hydroxyvitamin D with hypothyroidism…
View article: Evidence of familial resemblance and family-based heritability of food intakes derived from a longitudinal cohort study
Evidence of familial resemblance and family-based heritability of food intakes derived from a longitudinal cohort study Open
We sought to investigate the familial aggregation and family-based heritability of dietary intakes among adults in a population-based longitudinal study of the Tehran Lipid and Glucose Study (TLSG). Total of 4359 males and 5439 females ent…
View article: Association of physical activity with increased PI3K and Akt mRNA levels in adipose tissues of obese and non-obese adults
Association of physical activity with increased PI3K and Akt mRNA levels in adipose tissues of obese and non-obese adults Open
Phosphatidylinositol-3-kinase (PI3K)/Akt signaling pathway regulates glucose and lipid metabolism. We examined the association of PI3K and Akt expression in visceral (VAT) and subcutaneous adipose tissue (SAT) with daily physical activity …
View article: Cohort profile update: Tehran cardiometabolic genetic study
Cohort profile update: Tehran cardiometabolic genetic study Open
View article: Altered sialin mRNA gene expression in type 2 diabetic male Wistar rats: implications for nitric oxide deficiency
Altered sialin mRNA gene expression in type 2 diabetic male Wistar rats: implications for nitric oxide deficiency Open
View article: RET/PTC rearrangement in papillary thyroid carcinoma arising in malignant struma ovarii with abdominal wall metastasis and cervical thyroid gland: A case report and review of the literature
RET/PTC rearrangement in papillary thyroid carcinoma arising in malignant struma ovarii with abdominal wall metastasis and cervical thyroid gland: A case report and review of the literature Open
Background: Struma ovarii refers to rare mature cystic teratomas containing at least 50% of thyroid tissue, and malignant transformation is known to be even rarer. The synchronous development of malignant struma ovarii and cervical thyroid…