Marziyeh Aghazadeh
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View article: Enamel Maturation as a Systems Physiology: Ion Transport and Pi Flux
Enamel Maturation as a Systems Physiology: Ion Transport and Pi Flux Open
Dental enamel, the final product of amelogenesis, is a highly mineralized bioceramic that becomes acellular and non-regenerating after tooth eruption. This paper reviews literature that explores inorganic phosphate (Pi) transport during th…
View article: Induced mesenchymal stem cells generated from periodontal ligament fibroblast for regenerative therapy
Induced mesenchymal stem cells generated from periodontal ligament fibroblast for regenerative therapy Open
Bone fractures and bone loss represent significant global health challenges, with their incidence rising due to an aging population. Despite autologous bone grafts remain the gold standard for treatment, challenges such as limited bone ava…
View article: Effects of chitosan and TiO2 nanoparticles on the antibacterial property and ability to self-healing of cracks and retrieve mechanical characteristics of dental composites
Effects of chitosan and TiO2 nanoparticles on the antibacterial property and ability to self-healing of cracks and retrieve mechanical characteristics of dental composites Open
The aim of this study was to improve the self-healing properties of dental nanocomposite using nanoparticles of TiO2 and chitosan. We evaluated flexural and compressive strength, crack-healing, and self-healing lifespan after 3 …
View article: Evaluation of therapeutic effects of nanofibrous mat containing mycophenolate mofetil on oral lichen planus: In vitro and clinical trial study
Evaluation of therapeutic effects of nanofibrous mat containing mycophenolate mofetil on oral lichen planus: In vitro and clinical trial study Open
The characterization of nanofibrous mat approved the successful fabrication of scaffolds. The fabricated nanofibers showed notable antimicrobial activity. The amounts of TNF 𝛼, IL6, and reactive oxygen species (ROS) of stimulated human gin…
View article: Oral Health Indices in Patients With Type 2 Diabetes Receiving Insulin Treatment Compared With Metformin: A Cross-sectional Study
Oral Health Indices in Patients With Type 2 Diabetes Receiving Insulin Treatment Compared With Metformin: A Cross-sectional Study Open
Objectives: Due to the important influence of glycemic control on oral health, this study aimed to compare the gingival index and decayed, missing, filled teeth (DMFT) in participants with type 2 diabetes mellitus receiving insulin and met…
View article: Application of Novel VEGF-Loaded PCL-P Based Hybrid Copolymer Scaffold for Bone Regeneration
Application of Novel VEGF-Loaded PCL-P Based Hybrid Copolymer Scaffold for Bone Regeneration Open
Background: Polymeric materials are widely known as versatile materials, particularly for biomedical applications. The bioavailability, low toxicity, solubility, and permeability of this material play an essential role in biomedical implan…
View article: Synthesis, characterization, and evaluation of Hesperetin nanocrystals for regenerative dentistry
Synthesis, characterization, and evaluation of Hesperetin nanocrystals for regenerative dentistry Open
Hesperetin (HS), a metabolite of hesperidin, is a polyphenolic component of citrus fruits. This ingredient has a potential role in bone strength and the osteogenic differentiation. The bone loss in the orofacial region may occur due to the…
View article: A novel injectable hydrogel containing polyetheretherketone for bone regeneration in the craniofacial region
A novel injectable hydrogel containing polyetheretherketone for bone regeneration in the craniofacial region Open
View article: Synthesis and characterization of growth factor free nanoengineered bioactive scaffolds for bone tissue engineering
Synthesis and characterization of growth factor free nanoengineered bioactive scaffolds for bone tissue engineering Open
View article: MTA-Enriched Polymeric Scaffolds Enhanced the Expression of Angiogenic Markers in Human Dental Pulp Stem Cells
MTA-Enriched Polymeric Scaffolds Enhanced the Expression of Angiogenic Markers in Human Dental Pulp Stem Cells Open
Revascularization of the pulp tissue is one of the fundamental processes and challenges in regenerative endodontic procedures (REPs). In this regard, the current study is aimed at synthesizing the mineral trioxide aggregate- (MTA-) based s…
View article: The fabrication of halloysite nanotube-based multicomponent hydrogel scaffolds for bone healing
The fabrication of halloysite nanotube-based multicomponent hydrogel scaffolds for bone healing Open
Bone tissue engineering, as an alternative for common available therapeutic approaches, has been developed to focus on reconstructing of the missing tissues and restoring their functionality. In this work, three-dimensional (3D) nanocompos…
View article: Towards Induction of Angiogenesis in Dental Pulp Stem Cells Using Chitosan‐Based Hydrogels Releasing Basic Fibroblast Growth Factor
Towards Induction of Angiogenesis in Dental Pulp Stem Cells Using Chitosan‐Based Hydrogels Releasing Basic Fibroblast Growth Factor Open
Introduction . Chitosan is a natural biopolymer that attracted enormous attention in biomedical fields. The main components of regenerative endodontic procedures (REPs), as well as tissue engineering, are scaffolds, stem cells, and growth …
View article: The Antimicrobial, Antioxidative, and Anti-Inflammatory Effects of Polycaprolactone/Gelatin Scaffolds Containing Chrysin for Regenerative Endodontic Purposes
The Antimicrobial, Antioxidative, and Anti-Inflammatory Effects of Polycaprolactone/Gelatin Scaffolds Containing Chrysin for Regenerative Endodontic Purposes Open
The appropriate endodontic material should eliminate the infection and inflammation to provide a situation for regeneration and healing of pulp tissue besides biomineralization. Chrysin is one of the active ingredients of plant flavonoids,…
View article: Can Fixed Space Maintainers Have Adverse Effect on the Teeth and Periodontium?
Can Fixed Space Maintainers Have Adverse Effect on the Teeth and Periodontium? Open
BACKGROUND Space maintenance after premature loss of primary teeth is of importance in preventing space loss and potential crowding in future. Fixed space maintainers are used to prevent space loss but the presence of such fixed appliances…
View article: The comparison of oral health and xerostomia between hospitalized patients with schizophrenia and normal individuals
The comparison of oral health and xerostomia between hospitalized patients with schizophrenia and normal individuals Open
Background: Schizophrenia is a psychiatric illness characterized by negative symptoms (apathy, social withdrawal, lack of motivation) and cognitive deficits, while impairment in self-care, grooming, and oral health is also noted. This stud…
View article: The osteogenic differentiation of human dental pulp stem cells in alginate-gelatin/Nano-hydroxyapatite microcapsules
The osteogenic differentiation of human dental pulp stem cells in alginate-gelatin/Nano-hydroxyapatite microcapsules Open
View article: Overexpression Effects of miR‐424 and BMP2 on the Osteogenesis of Wharton’s Jelly‐Derived Stem Cells
Overexpression Effects of miR‐424 and BMP2 on the Osteogenesis of Wharton’s Jelly‐Derived Stem Cells Open
Recently, the translational application of noncoding RNAs is accelerated dramatically. In this regard, discovering therapeutic roles of microRNAs by developing synthetic RNA and vector‐based RNA is attracting attention. Here, we studied th…
View article: Development and biocompatibility of the injectable collagen/nano-hydroxyapatite scaffolds as <i>in situ</i> forming hydrogel for the hard tissue engineering application
Development and biocompatibility of the injectable collagen/nano-hydroxyapatite scaffolds as <i>in situ</i> forming hydrogel for the hard tissue engineering application Open
Injectable hydrogels attract more attention to hard tissue engineering for the fulfilment of the defects with irregular shapes. Therefore, the researchers investigated the biocompatibility and immune response to the injectable PCL-PEG-PCL-…
View article: The Osteogenic Differentiation of Mesenchymal Stem Cells Derived From Dental Pulp in Modular Alginate-gelatin/nano-hydroxyapatite Microcapsules
The Osteogenic Differentiation of Mesenchymal Stem Cells Derived From Dental Pulp in Modular Alginate-gelatin/nano-hydroxyapatite Microcapsules Open
Background Microcapsule is considered as a promising 3D microenvironment for Bone Tissue Engineering (BTE) applications. Microencapsulation of cells in an appropriate scaffold not only protects cells against excess stress but also promotes…
View article: Synthesis and in vitro Evaluation of Thermosensitive PLA-g-P(HEM-co-NIPAAM) Hydrogel Used for Delivery of VEGF
Synthesis and in vitro Evaluation of Thermosensitive PLA-g-P(HEM-co-NIPAAM) Hydrogel Used for Delivery of VEGF Open
Bone has self-healing potential, but this characteristic is limited and requires external intervention. Bone formation is a dynamic process influenced by various growth factors. Angiogenesis is a fundamental phase and essential in the earl…
View article: The Osteogenic Differentiation of Mesenchymal Stem Cells Derived from Dental Pulp in Modular Alginate-Gelatin/Nano-Hydroxyapatite Microcapsules
The Osteogenic Differentiation of Mesenchymal Stem Cells Derived from Dental Pulp in Modular Alginate-Gelatin/Nano-Hydroxyapatite Microcapsules Open
Background Microcapsule is considered as a promising 3D microenvironment for Bone Tissue Engineering (BTE) applications. Microencapsulation of cells in an appropriate scaffold not only protects cells against excess stress but also promotes…
View article: Gingerly effervescent tablets: investigating the effect of cytotoxicity on gingival fibroblasts and antimicrobial properties under laboratory conditions
Gingerly effervescent tablets: investigating the effect of cytotoxicity on gingival fibroblasts and antimicrobial properties under laboratory conditions Open
Ginger is a medicinal plant with antioxidant, anti-bacterial, anti-inflammatory and anti-fungal properties. The shape of effervescent tablet is a new form of this product for use as a mouthwash. This study investigated the cytotoxicity and…
View article: Towards osteogenic differentiation of human dental pulp stem cells on PCL-PEG-PCL/zeolite nanofibrous scaffolds
Towards osteogenic differentiation of human dental pulp stem cells on PCL-PEG-PCL/zeolite nanofibrous scaffolds Open
Presently, tissue engineering has been developed as an effective option in the restoration and repair of tissue defects. One of the tissue engineering strategies is to use both biodegradable scaffolds and stimulating factors for enhancing …