Masahiro Sugiura
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View article: Author Correction: The heavy chain of 4F2 antigen promote prostate cancer progression via SKP-2
Author Correction: The heavy chain of 4F2 antigen promote prostate cancer progression via SKP-2 Open
View article: Development of an In Vitro Chloroplast Splicing System: Sequences Required for Correct pre-mRNA Splicing
Development of an In Vitro Chloroplast Splicing System: Sequences Required for Correct pre-mRNA Splicing Open
Chloroplast genomes in land plants include approximately 20 intron-containing genes. Most of the introns are similar to the group II introns found in fungi, algae and some bacteria, but no self-splicing has been reported. To analyze splici…
View article: Functional analysis of LAT3 in prostate cancer: Its downstream target and relationship with androgen receptor
Functional analysis of LAT3 in prostate cancer: Its downstream target and relationship with androgen receptor Open
L‐type amino acid transporter 3 (LAT3, SLC43A1 ) is abundantly expressed in prostate cancer (PC) and is thought to play an essential role in PC progression through the cellular uptake of essential amino acids. Here, we analyzed the express…
View article: The heavy chain of 4F2 antigen promote prostate cancer progression via SKP-2
The heavy chain of 4F2 antigen promote prostate cancer progression via SKP-2 Open
View article: Characterization of The Expression of The Heavy Chain of 4F2 Antigen As a Therapeutic Target in Prostate Cancer
Characterization of The Expression of The Heavy Chain of 4F2 Antigen As a Therapeutic Target in Prostate Cancer Open
The 4F2 cell-surface antigen heavy chain (4F2hc) forms a heterodimeric complex with L-type amino acid transporter 1 (LAT1) and transports large neutral essential amino acids. However, in contrast to the traditional role of LAT1 in various …
View article: Epigenetic modifications in prostate cancer
Epigenetic modifications in prostate cancer Open
Prostate cancer is a major cause of cancer‐related deaths among men worldwide. In addition to genomic alterations, epigenetic alterations accumulated in prostate cancer have been elucidated. While aberrant deoxyribonucleic acid hypermethyl…
View article: Identification of AR-V7 downstream genes commonly targeted by AR/AR-V7 and specifically targeted by AR-V7 in castration resistant prostate cancer
Identification of AR-V7 downstream genes commonly targeted by AR/AR-V7 and specifically targeted by AR-V7 in castration resistant prostate cancer Open
View article: Presence of compensated and primary hypogonadism is related to ISUP Grade Groups 3-5 prostate cancer diagnosis
Presence of compensated and primary hypogonadism is related to ISUP Grade Groups 3-5 prostate cancer diagnosis Open
View article: Expression of L-type amino acid transporter 1 as a molecular target for prognostic and therapeutic indicators in bladder carcinoma
Expression of L-type amino acid transporter 1 as a molecular target for prognostic and therapeutic indicators in bladder carcinoma Open
L-type amino acid transporter 1 (LAT1) plays a role in transporting essential amino acids including leucine, which regulates the mTOR signaling pathway. Here, we studied the expression profile and functional role of LAT1 in bladder cancer.…
View article: MP51-04 AN L-TYPE AMINO ACID TRANSPORTER 1 INHIBITOR: JPH203 SUPPRESSES BLADDER CANCER GROWTH AND INVASION VIA IGFBP-5
MP51-04 AN L-TYPE AMINO ACID TRANSPORTER 1 INHIBITOR: JPH203 SUPPRESSES BLADDER CANCER GROWTH AND INVASION VIA IGFBP-5 Open
You have accessJournal of UrologyBladder Cancer: Basic Research & Pathophysiology I (MP51)1 Apr 2019MP51-04 AN L-TYPE AMINO ACID TRANSPORTER 1 INHIBITOR: JPH203 SUPPRESSES BLADDER CANCER GROWTH AND INVASION VIA IGFBP-5 Maihulan Maimaiti*, …
View article: Region-specific alteration of histone modification by LSD1 inhibitor conjugated with pyrrole-imidazole polyamide
Region-specific alteration of histone modification by LSD1 inhibitor conjugated with pyrrole-imidazole polyamide Open
Epigenome regulates gene expression to determine cell fate, and accumulation of epigenomic aberrations leads to diseases, including cancer. NCD38 inhibits lysine-specific demethylase-1 (LSD1), a histone demethylase targeting H3K4me1 and H3…
View article: Contralateral adrenal width predicts the duration of prolonged post‐surgical steroid replacement for subclinical Cushing syndrome
Contralateral adrenal width predicts the duration of prolonged post‐surgical steroid replacement for subclinical Cushing syndrome Open
Objectives To identify pre‐treatment factors affecting the duration of post‐surgical steroid replacement in patients undergoing adrenalectomy for subclinical Cushing syndrome. Methods The present retrospective analysis included 64 patients…
View article: Significant prognostic difference between Grade Group 4 and 5 in the 2014 International Society of Urological Pathology Grading System for High Grade Prostate Cancer with Bone Metastasis
Significant prognostic difference between Grade Group 4 and 5 in the 2014 International Society of Urological Pathology Grading System for High Grade Prostate Cancer with Bone Metastasis Open
Background: To investigate prognostic difference between Gleason Score (GS) 8 and 9–10, as the 2014 International Society of Urological Pathology Gleason Grading Systems proposed, in patients with prostate cancer (PCa) with bone metastasis…
View article: Treatment of locally advanced prostate cancer (Stage T3)
Treatment of locally advanced prostate cancer (Stage T3) Open
Aggressive treatment with short-term androgen deprivation for locally advanced prostate cancer could be beneficial and not harmful when suitable candidates are selected. Delayed androgen deprivation was effective for no adjuvant patients a…
View article: Outcomes of patients older than 75 years with non-metastatic prostate cancer
Outcomes of patients older than 75 years with non-metastatic prostate cancer Open