Masahiro Takeo
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View article: Decoding emergent properties of microbial community functions through sub-community observations and interpretable machine learning
Decoding emergent properties of microbial community functions through sub-community observations and interpretable machine learning Open
The functions of microbial communities, including substrate conversion and pathogen suppression, arise not as a simple sum of individual species’ capabilities but through complex interspecies interactions. Understanding how such functions …
View article: Decoding emergent properties of microbial community functions through subcommunity observations and interpretable machine learning
Decoding emergent properties of microbial community functions through subcommunity observations and interpretable machine learning Open
The functions of microbial communities, including substrate conversion and pathogen suppression, arise not as a simple sum of individual species’ capabilities but through complex interspecies interactions. Understanding how such functions …
View article: Complete genome sequence of hydroquinonesulfonate-assimilating bacterium, <i>Delftia lacustris</i> HQS1
Complete genome sequence of hydroquinonesulfonate-assimilating bacterium, <i>Delftia lacustris</i> HQS1 Open
We report the complete genome assembly of a hydroquinonesulfonate-assimilating bacterium, Delftia lacustris strain HQS1. This strain contains one circular chromosome (6,979,964 bp) and one circular plasmid (39,999 bp). The chromosomal sequ…
View article: Significance Evaluating Coagulation-Fibrinolysis Dynamics in Chronic Thromboembolic Pulmonary Disease With Pulmonary Hypertension Caused by Heritable Thrombophilias: A Case Series
Significance Evaluating Coagulation-Fibrinolysis Dynamics in Chronic Thromboembolic Pulmonary Disease With Pulmonary Hypertension Caused by Heritable Thrombophilias: A Case Series Open
Precisely evaluating coagulation ability is crucial for managing hypercoagulation. Antithrombin resistance is a disease in which a missense variant of the prothrombin gene, prothrombin Yukuhashi, occurs in a hypercoagulation state. We pres…
View article: Tumor Cell Implantation from an Oral Advanced Cancer at the Rectal Endoscopic Submucosal Dissection Site: A Case Report and Literature Review
Tumor Cell Implantation from an Oral Advanced Cancer at the Rectal Endoscopic Submucosal Dissection Site: A Case Report and Literature Review Open
This report and literature review explores cases of tumor cell implantation at colorectal post-endoscopic resection sites. We detail a unique case in which advanced rectosigmoid colon cancer cells would implant into an endoscopic submucosa…
View article: Proximal superficial femoral artery puncture using an ascending approach for stent re-occlusion in the common femoral artery
Proximal superficial femoral artery puncture using an ascending approach for stent re-occlusion in the common femoral artery Open
View article: Isolation and Characterization of Two Hydroxylated Aromatic Sulfonate-Assimilating Bacterial Strains, <i>Cupriavidus basilensis </i>PSY7 and <i>Delftia lacustris </i>HQS1, from Activated Sludge
Isolation and Characterization of Two Hydroxylated Aromatic Sulfonate-Assimilating Bacterial Strains, <i>Cupriavidus basilensis </i>PSY7 and <i>Delftia lacustris </i>HQS1, from Activated Sludge Open
View article: Pseudoaneurysm of mitral-aortic intervalvular fibrosa with rupture: a case report
Pseudoaneurysm of mitral-aortic intervalvular fibrosa with rupture: a case report Open
View article: Advanced technical tips and recent insights in ERCP using balloon‐assisted endoscopy
Advanced technical tips and recent insights in ERCP using balloon‐assisted endoscopy Open
Pancreatobiliary endoscopic interventions using balloon‐assisted endoscopes have been widely acknowledged as the first‐line therapy for pancreatobiliary diseases in postoperative patients with reconstructed gastrointestinal anatomy (exclud…
View article: Perforation-free removal of gastric gastrointestinal stromal tumors: Endoscopic inversion and strangulation of muscle layer and resection (EISMR)
Perforation-free removal of gastric gastrointestinal stromal tumors: Endoscopic inversion and strangulation of muscle layer and resection (EISMR) Open
Endoscopic resection for GIST has become more widespread in recent years because it is less invasive than surgery. However, when endoscopic resection is performed, a full-layer resection of the gastric wall is often necessary, and extensiv…
View article: Vertical Chemical Unit Operation Using Microcapillary Arrays for Immunosorbent Assay
Vertical Chemical Unit Operation Using Microcapillary Arrays for Immunosorbent Assay Open
In order to detect substances using microfluidic devices, fluidic filters with microcapillary arrays with a high aspect ratio were fabricated using deep X-ray lithography. Also, the pressure required to move the solution held on the filter…
View article: Novel Concepts for Graphene-Based Nanomaterials Synthesis for Phenol Removal from Palm Oil Mill Effluent (POME)
Novel Concepts for Graphene-Based Nanomaterials Synthesis for Phenol Removal from Palm Oil Mill Effluent (POME) Open
In recent years, the global population has increased significantly, resulting in elevated levels of pollution in waterways. Organic pollutants are a major source of water pollution in various parts of the world, with phenolic compounds bei…
View article: Micro Stirrer with Heater Mounted on SAW Actuator for High-speed Chemical Reaction
Micro Stirrer with Heater Mounted on SAW Actuator for High-speed Chemical Reaction Open
Mixing is difficult in microfluidic devices due to the low Reynolds' number. We proposed and demonstrated a surface-acoustic-wave (SAW)-based microfluidic system which can control the temperature by mounting a heater. This device has a hol…
View article: Viral Infection in Esophageal, Gastric, and Colorectal Cancer
Viral Infection in Esophageal, Gastric, and Colorectal Cancer Open
The human gastrointestinal tract, which constitutes the digestive system, contains a large number of virus particles that maintain organizational homeostasis and health. Conversely, viral pathogens have also attracted attention for their i…
View article: Gel Immersion Endoscopic Mucosal Resection (EMR) for Superficial Nonampullary Duodenal Epithelial Tumors May Reduce Procedure Time Compared with Underwater EMR (with Video)
Gel Immersion Endoscopic Mucosal Resection (EMR) for Superficial Nonampullary Duodenal Epithelial Tumors May Reduce Procedure Time Compared with Underwater EMR (with Video) Open
Background/Aims. Underwater endoscopic mucosal resection (UEMR) has recently attracted attention as a safe and effective method for superficial nonampullary duodenal epithelial tumors (SNADETs). However, water is a fluid and it does not re…
View article: Manipulation of Powder with Surface Acoustic Wave Actuator to Control Standing and Traveling Modes
Manipulation of Powder with Surface Acoustic Wave Actuator to Control Standing and Traveling Modes Open
View article: A giant Brunner gland hamartoma successfully treated by endoscopic excision followed by transanal retrieval
A giant Brunner gland hamartoma successfully treated by endoscopic excision followed by transanal retrieval Open
Rationale: Brunner gland hamartoma (BGH) is a rare tumor of the duodenum. Although BGH is a benign tumor, larger lesion with gastrointestinal symptoms requires tumor removal. We report a giant BGH, successfully treated by endoscopic excisi…
View article: Degradation Potential of the Nonylphenol Monooxygenase of Sphingomonas sp. NP5 for Bisphenols and Their Structural Analogs
Degradation Potential of the Nonylphenol Monooxygenase of Sphingomonas sp. NP5 for Bisphenols and Their Structural Analogs Open
The nonylphenol-degrading bacterium Sphingomonas sp. strain NP5 has a very unique monooxygenase that can attack a wide range of 4-alkylphenols with a branched side chain. Due to the structural similarity, it can also attack bisphenolic com…
View article: Draft Genome Sequence of a Bioflocculant-Producing Bacterium, Citrobacter freundii IFO 13545
Draft Genome Sequence of a Bioflocculant-Producing Bacterium, Citrobacter freundii IFO 13545 Open
Here, we report the 5.2-Mb genome sequence of a bioflocculant-producing bacterial strain, Citrobacter freundii IFO 13545, which consists of 5,209,670 bp with a G+C content of 51.5% and 4,853 predicted coding sequences (CDSs). The genes rel…
View article: Preparation of 1L-<i>myo-</i>Inositol 1-Phosphate as a Substrate of Phosphatidylinositol Phosphate Synthase
Preparation of 1L-<i>myo-</i>Inositol 1-Phosphate as a Substrate of Phosphatidylinositol Phosphate Synthase Open
Novel drugs possessing a mechanism of action specific to pathogenic mycobacteria, including Mycobacterium tuberculosis, are needed. In 2010, we discovered that the biosynthetic pathway of phosphatidylinositol, which is a membrane phospholi…
View article: Structural basis of the correct subunit assembly, aggregation, and intracellular degradation of nylon hydrolase
Structural basis of the correct subunit assembly, aggregation, and intracellular degradation of nylon hydrolase Open
Nylon hydrolase (NylC) is initially expressed as an inactive precursor (36 kDa). The precursor is cleaved autocatalytically at Asn266/Thr267 to generate an active enzyme composed of an α subunit (27 kDa) and a β subunit (9 kDa). Four αβ he…
View article: Biosynthetic Pathway and Genes of Chitin/Chitosan-Like Bioflocculant in the Genus Citrobacter
Biosynthetic Pathway and Genes of Chitin/Chitosan-Like Bioflocculant in the Genus Citrobacter Open
Chitin/chitosan, one of the most abundant polysaccharides in nature, is industrially produced as a powder or flake form from the exoskeletons of crustaceans such as crabs and shrimps. Intriguingly, many bacterial strains in the genus Citro…
View article: Correction to: Metabolic pathway of 6-aminohexanoate in the nylon oligomer-degrading bacterium Arthrobacter sp. KI72: identification of the enzymes responsible for the conversion of 6-aminohexanoate to adipate
Correction to: Metabolic pathway of 6-aminohexanoate in the nylon oligomer-degrading bacterium Arthrobacter sp. KI72: identification of the enzymes responsible for the conversion of 6-aminohexanoate to adipate Open
View article: Simple ELISA using Polyclonal Antibody and Lectin for Determination of Soluble Chitosan - Like Polysaccharide in Bacterial Culture
Simple ELISA using Polyclonal Antibody and Lectin for Determination of Soluble Chitosan - Like Polysaccharide in Bacterial Culture Open
We have developed a simple enzyme-linked immunosorbent assay (ELISA) for the direct determination of chitosan-like polysaccharide (CP) produced in the cultures of Citrobacter strains. CP in sample solutions was reacted with anti-CP rabbit …
View article: Simple ELISA using Polyclonal Antibody and Lectin for Determination of Soluble Chitosan - Like Polysaccharide in Bacterial Culture
Simple ELISA using Polyclonal Antibody and Lectin for Determination of Soluble Chitosan - Like Polysaccharide in Bacterial Culture Open
We have developed a simple enzyme-linked immunosorbent assay (ELISA) for the direct determination of chitosan-like polysaccharide (CP) produced in the cultures of Citrobacter strains. CP in sample solutions was reacted with anti-CP rabbit …
View article: Draft Genome Sequence of the Nylon Oligomer-Degrading Bacterium <i>Arthrobacter</i> sp. Strain KI72
Draft Genome Sequence of the Nylon Oligomer-Degrading Bacterium <i>Arthrobacter</i> sp. Strain KI72 Open
We report here the 4.6-Mb genome sequence of a nylon oligomer-degrading bacterium, Arthrobacter sp. strain KI72. The draft genome sequence of strain KI72 consists of 4,568,574 bp, with a G+C content of 63.47%, 4,372 coding sequences (CDSs)…
View article: Mutations affecting the internal equilibrium of the reaction catalyzed by 6‐aminohexanoate‐dimer hydrolase
Mutations affecting the internal equilibrium of the reaction catalyzed by 6‐aminohexanoate‐dimer hydrolase Open
The enzyme 6‐aminohexanoate‐dimer hydrolase catalyzes amide synthesis. The yield of this reverse reaction in 90% t ‐butyl alcohol was found to vary drastically when enzyme mutants with substitutions of several amino acids located at the en…
View article: Smad2/3 Linker Phosphorylation Is a Possible Marker of Cancer Stem Cells and Correlates with Carcinogenesis in a Mouse Model of Colitis-Associated Colorectal Cancer
Smad2/3 Linker Phosphorylation Is a Possible Marker of Cancer Stem Cells and Correlates with Carcinogenesis in a Mouse Model of Colitis-Associated Colorectal Cancer Open
pSmad3L-Ser signalling is an early event in colitis-associated colorectal cancer, and pSmad2/3L-Thr immunostaining-positive cells might be cancer stem cells.