Masahisa Nozaki
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View article: SQSTM1L341V variant that is linked to sporadic ALS exhibits impaired association with MAP1LC3 in cultured cells
SQSTM1L341V variant that is linked to sporadic ALS exhibits impaired association with MAP1LC3 in cultured cells Open
Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are genetically, pathologically and clinically-related progressive neurodegenerative diseases. Thus far, several SQSTM1 variations have been identified in patients with …
View article: Additional file 5: of Systemic overexpression of SQSTM1/p62 accelerates disease onset in a SOD1H46R-expressing ALS mouse model
Additional file 5: of Systemic overexpression of SQSTM1/p62 accelerates disease onset in a SOD1H46R-expressing ALS mouse model Open
Figure S5. Immunoblot-images used for the quantitative analysis in Fig. 6b. The immunoblots of (a) soluble misfolded SOD1 and GAPDH, (b) insoluble misfolded SOD1 and actin were analyzed for the quantitative analysis (Fig. 6b). The spinal c…
View article: Additional file 4: of Systemic overexpression of SQSTM1/p62 accelerates disease onset in a SOD1H46R-expressing ALS mouse model
Additional file 4: of Systemic overexpression of SQSTM1/p62 accelerates disease onset in a SOD1H46R-expressing ALS mouse model Open
Figure S4. Immunoblot-images used for the quantitative analysis in Figs. 6a and Fig. 7. The immunoblots of (a) soluble SOD1, (b) insoluble SOD1 monomer (Mono), (c) insoluble high-molecular weight (HMW) SOD1, (d) soluble SQSTM1, (e) insolu…