Explanipedia

Pregnancy with mixed connective tissue disease: Exploration of factors influencing live birth outcomes Open

Tsukasa Yoshida, Jun Takeda, Sumire Ishii, Masakazu Matsushita, Naoto Tamura , et al. · 2024

Mixed connective tissue disease (MCTD) predominantly affects women in their reproductive age (30–40 years). This study is aimed to analyze a case series of MCTD-complicated pregnancies. The study design utilized a combined case-series and …

Pregnancy with Mixed Connective Tissue Disease: exploration of factors influencing live birth outcomes Open

Tsukasa Yoshida, Jun Takeda, Sumire Ishii, Masakazu Matsushita, Naoto Tamura , et al. · 2024

Background Mixed connective tissue disease (MCTD) predominantly affects women in their reproductive age (30–40 years). This study is aimed to analyze a case series of MCTD-complicated pregnancies. Methods The study design utilized a combin…

Prognostic analysis of pulmonary hypertension with lung parenchymal lesion: Comparison of mortality with and without connective tissue disease Open

Yoshifumi Suzuki, Tetsutaro Nagaoka, Yuriko Terayama, Yuichi Nagata, Takashi Yoshida , et al. · 2023

Treatment with a pulmonary vasodilator for CTD-IP PH may improve the prognosis, even in patients requiring LTOT.

Critical role of lectin pathway mediated by MBL-associated serine proteases in complement activation for the pathogenesis in systemic lupus erythematosus Open

Yuko Asanuma, Kazuhisa NOZAWA, Masakazu Matsushita, Makio Kusaoi, Yoshiyuki Abe , et al. · 2023

In complement activation system, although the classical pathway has shown to play a critical role for the pathogenesis of SLE, the role of lectin pathway has remained unknown in the pathogenesis of SLE. As Mannose-binding lectin-associated…

Synovial Tissue Heterogeneity in Japanese Patients With Rheumatoid Arthritis Elucidated Using a Cell‐Type Deconvolution Approach Open

S. Nakajima, Haruka Tsuchiya, Mineto Ota, Megumi Ogawa, Saeko Yamada , et al. · 2023

Objective Recent advances in single‐cell RNA sequencing technology have improved our understanding of the immunological landscape of rheumatoid arthritis (RA). We aimed to stratify the synovium from East Asian patients with RA by immune ce…

AB0717 DIAGNOSIS OF CRANIAL GIANT CELL ARTERITIS IN JAPAN USING VASCULAR ULTRASONOGRAPHY COMBINED WITH OTHER COMPLEMENTARY IMAGING METHODS Open

Takeshi Kawamoto, Michihiro Ogasawara, Y. Mastuki-Muramoto, Mariko Harada, Eri Hayashi , et al. · 2023

AB0572 DIFFERENTIAL BACKGROUND OF CLINICAL AND IMMUNOHISTOLOGICAL CHARACTRSITICS IN SYSTEMIC LUPUS ERYTHEMATOSUS AND RHEUMATOID ARTHRITIS COMPLICATED WITH HEART DISEASE Open

Takeshi Kawamoto, Hirofumi Amano, Satoshi Matsushita, K. Minowa, Masakazu Matsushita , et al. · 2023

Physician approval for pregnancy in patients with SLE showing only serological activity: A vignette survey study Open

Sakiko Isojima, Nobuyuki Yajima, Ryo Yanai, Yoko Miura, Shingo Fukuma , et al. · 2022

Background: The EULAR recommendation requires that the disease activity of systemic lupus erythematosus before pregnancy be stable because pregnancy complications and disease flares increase if pregnancy occurs while systemic lupus erythem…

POS0734 THE CLINICAL JUDGMENT FOR THE ACCEPTABILITY OF PREGNANCY IN PATIENTS WITH SEROLOGICALLY ACTIVE SLE IN JAPAN: A NATIONWIDE ONLINE SURVEY FROM THE VIGNETTE STUDY Open

Sakiko Isojima, Nobuyuki Yajima, Ryo Yanai, Yoshihiko Miura, S Fukuma , et al. · 2022

OP0238 CLINICAL ANALYSIS OF 34 CASES OF CARDIAC COMPLICATIONS REQUIRING SURGICAL INTERVENTION IN SYSTEMIC LUPUS ERYTHEMATOSUS AND ASSESSMENT ABOUT MECHANISM OF DEVELOPMENT WITH IMMUNOLOGICAL ANALYSIS Open

Takeshi Kawamoto, H. Amano, Satoshi Matsushita, K. Minowa, Masakazu Matsushita , et al. · 2022

Periostin‐related progression of different types of experimental pulmonary hypertension: A role for M2 macrophage and FGF‐2 signalling Open

Takashi Yoshida, Tetsutaro Nagaoka, Yuichi Nagata, Yoshifumi Suzuki, Takeo Tsutsumi , et al. · 2022

Background and objective Remodelling of pulmonary arteries (PA) contributes to the progression of pulmonary hypertension (PH). Periostin, a matricellular protein, has been reported to be involved in the development of PH. We examined the r…

Effect of Prophylactic Dose of Trimethoprim-Sulfamethoxazole on Serum Creatinine in Japanese Patients With Connective Tissue Diseases Open

Rui Kawato, Ryo Rokutanda, Masato Okada, Masakazu Matsushita, Ken Yamaji , et al. · 2022

Objectives: At normal doses of trimethoprim-sulfamethoxazole (TMP/SMX), trimethoprim inhibits tubular creatinine secretion, leading to a rapid but reversible increase in serum creatinine (SCr). Although patients with connective tissue dise…

Seroprevalence of anti-SARS-CoV-2 antibodies in Japanese COVID-19 patients Open

Makoto Hiki, Yoko Tabe, Tomohiko Ai, Yuya Matsue, Norihiro Harada , et al. · 2021

Objectives To determine the seroprevalence of anti-SARS-CoV-2 IgG and IgM antibodies in symptomatic Japanese COVID-19 patients. Methods Serum samples (n = 114) from 34 COVID-19 patients with mild to critical clinical manifestations were ex…

Application of gamma radiation for disinfection of fungi in a large volume of historical archives damaged by flood following Typhoon Hagibis 2019, Japan: A case report Open

Nguyen Thi Thuy Linh, Yuko Kumeda, Masakazu Matsushita, Takayuki Hironiwa, Masakazu Furuta · 2021

A large volume of historical archives was extensively damaged by flood water, following Typhoon Hagibis in Fukushima, Japan, in October 2019. They were rescued from the stricken area within a week, however, the prolonged exposure of paper …

FRI0179 A STUDY ON THE ACHIEVEMENT OF LUPUS LOW DISEASE ACTIVITY STATE AND QUALITY OF LIFE IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS: FROM THE JUNTENDO UNIVERSITY SLE PROSPECTIVE REGISTRY STUDY Open

Masakazu Matsushita, Hirofumi Amano, Kazuki Nozawa, Michihiro Ogasawara, Kurisu Tada , et al. · 2020

SAT0262 PROPOSAL FOR OPTIMIZATION OF DIAGNOSTIC IMAGING FOR GIANT CELL ARTERITIS USING THREE-DIMENSIONAL COMPUTED TOMOGRAPHY ANGIOGRAPHY IMAGE AND CONSTRUCTING VASCULAR MAPPING FROM VASCULAR ULTRASONOGRAPHY AS REFERENCES Open

Terufumi Kawamoto, Michihiro Ogasawara, Y. Mastuki-Muramoto, Tomohiro Kawaguchi, Shion Ando , et al. · 2020

AB0422 LEFT VENTRICULAR ABNORMALITIES IN SYSTEMIC LUPUS ERYTHEMATOSUS PATIENTS FOLLOWED BY SEQUENTIAL ECHOCARDIOGRAPHY Open

Taiga Kuga, Masakazu Matsushita, Kurisu Tada, Katsuhiko Yamaji, Naoaki Tamura · 2020

Methotrexate and Oral Antirheumatic Drugs Open

Kwang‐Seok Yang, Masakazu Matsushita, Naoto Tamura · 2020

Methotrexate (MTX) and biological agents have revolutionized the rheumatoid arthritis (RA) treatment by shifting the focus from alleviating pain to preventing joint degeneration, improving the quality of life and remission of the disease. …

Extra-articular Manifestations of Rheumatoid Arthritis Open

Masakazu Matsushita, Ken Yamaji, Naoto Tamura · 2020

Rheumatoid arthritis (RA) is a chronic inflammatory disease that causes persistent inflammation, primarily in the synovial membrane of the joints. It may cause joint pain, swelling, and even deformation. Due to the strong involvement of ab…

Diagnosis of giant cell arteritis by head-contrast three-dimensional computed tomography angiography: two case reports Open

Toshio Kawamoto, Michihiro Ogasawara, Souichiro Nakano, Yuko Matsuki−Muramoto, Masakazu Matsushita , et al. · 2019

AB0528 ANALYSIS OF THE CASES OF 33 SLE PATIENTS THAT NECESSITATED CARDIOVASCULAR SURGERY Open

Toshio Kawamoto, Satoshi Matsushita, Hirofumi Amano, Kentaro Minowa, Mai Yoshida , et al. · 2019

FRI0329 ANALYSIS OF 11 CASES OF ANTI-PL-7 ANTIBODY POSITIVE PATIENTS WITH IDIOPATHIC INFLAMMATORY MYOPATHIES. MALIGNANCY MAY NOT BE UNCOMMON COMPLICATION IN ANTI-PL-7 ANTIBODY POSITIVE MYOSITIS PATIENTS Open

Taiga Kuga, Yoshiyuki Abe, Masakazu Matsushita, Kurisu Tada, Ken Yamaji , et al. · 2019

096. CONSIDERATION OF PICTURE IMAGES AND ESTABLISHMENT OF FOUNDATION KNOWLEDGE FOR ERADICATE BLINDNESS ABOUT GIANT CELL ARTERITIS Open

Toshio Kawamoto, Michihiro Ogasawara, Soichiro Nakano, Yuko Matsuki, Masakazu Matsushita , et al. · 2019

Changes in antibody titres in patients with anti-transcription intermediary factor 1-gamma antibody-positive idiopathic inflammatory myositis Open

Yoshiyuki Abe, Taiki Ando, Masakazu Matsushita, Kurisu Tada, Ken Yamaji , et al. · 2018

THU0734-HPR Novel experience equipment for rheumatoid hand-fingers Open

Masazumi KUSUMOTO, Shuji TSUJI, M. Toshiharu, Y. Kushimoto, Noboru Ise , et al. · 2018

A case of ankylosing spondylitis with concurrent Takayasu arteritis Open

Masakazu Matsushita, S Kobayashi, Kurisu Tada, Eri Hayashi, Ken Yamaji , et al. · 2018

We herein report a case involving a 56-year-old man who had experienced neck and lower back pain since the age of 23 years. Ankylosing spondylitis (AS) was diagnosed at 41 years of age, and treatment with sulfasalazine was initiated. At 44…

The Association of Anti-Aminoacyl-Transfer Ribonucleic Acid Synthetase Antibodies in Patients With Rheumatoid Arthritis and Interstitial Lung Disease Open

Masakazu Matsushita · 2018

Objectives: This study aims to analyze the distribution and clinicopathological characteristics of anti-aminoacyl-transfer ribonucleic acid (tRNA) synthetase (ARS) antibodies in rheumatoid arthritis patients. Patients and methods: We retro…

Clinical characteristics and change in the antibody titres of patients with anti-MDA5 antibody–positive inflammatory myositis Open

Yoshiyuki Abe, Masakazu Matsushita, Kurisu Tada, Ken Yamaji, Yoshinari Takasaki , et al. · 2017

An initial decrease in anti-MDA5 antibody titre after commencement of treatment was observed in most of the patients, including in fatal cases, suggesting that this may not necessarily be a useful marker for treatment of patients with DM.

Cholesterol levels of Japanese dyslipidaemic patients with various comorbidities: BioBank Japan Open

Hiroshi Yokomichi, Hokuto Noda, Akiko Nagai, Makoto Hirata, Akiko Tamakoshi , et al. · 2017

These data provide details of serum cholesterol levels by risk-factor profile in patients with dyslipidaemia and could add evidence of treatment decisions.

The synovial grade corresponding to clinically involved joints and a feasible ultrasound-adjusted simple disease activity index for monitoring rheumatoid arthritis Open

Yusuke Yamada, Michihiro Ogasawara, Misa Gorai, Yuko Matsuki, Go Murayama , et al. · 2016

Objectives: To determine which grade of ultrasound (US) synovitis corresponds to clinically involved joints in rheumatoid arthritis (RA) and develops a new US-adjusted composite measure. Methods: Clinical and US examinations …

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