Masaki Ieda
YOU?
Author Swipe
View article: Association between the baseline health status and long-term outcomes after catheter ablation for atrial fibrillation
Association between the baseline health status and long-term outcomes after catheter ablation for atrial fibrillation Open
View article: Tropheryma whipplei Endocarditis Diagnosed by Tissue 16S rRNA Gene Sequencing: A Case Report
Tropheryma whipplei Endocarditis Diagnosed by Tissue 16S rRNA Gene Sequencing: A Case Report Open
View article: Evolution and Challenges of Physician-Led Home Visits in Japan
Evolution and Challenges of Physician-Led Home Visits in Japan Open
View article: Heart failure-specific cardiac fibroblasts contribute to cardiac dysfunction via the MYC–CXCL1–CXCR2 axis
Heart failure-specific cardiac fibroblasts contribute to cardiac dysfunction via the MYC–CXCL1–CXCR2 axis Open
Heart failure (HF) is a growing global health issue. While most studies focus on cardiomyocytes, here we highlight the role of cardiac fibroblasts (CFs) in HF. Single-cell RNA sequencing of mouse hearts under pressure overload identified s…
View article: Age and Health Status Benefits Following Initiation of Atrial Fibrillation‐Specific Treatments
Age and Health Status Benefits Following Initiation of Atrial Fibrillation‐Specific Treatments Open
Background Atrial fibrillation (AF) is managed with various strategies, including rate and rhythm control, to improve patients' health status. Although its incidence increases with age, how age affects health status improvements following …
View article: Mechanisms Underlying Superior Clinical Outcomes of Transcatheter Aortic Valve Implantation with the Latest Balloon-Expandable Valve
Mechanisms Underlying Superior Clinical Outcomes of Transcatheter Aortic Valve Implantation with the Latest Balloon-Expandable Valve Open
Transcatheter aortic valve implantation (TAVI) using SAPIEN 3 Ultra RESILIA (S3UR) offers improved hemodynamic performance than its former generation, SAPIEN 3 (S3). This study compared 1-year clinical outcomes after TAVI using S3UR and S3…
View article: Impact of Peridevice Leak on Clinical Outcomes After Left Atrial Appendage Closure: The OCEAN‐LAAC Registry
Impact of Peridevice Leak on Clinical Outcomes After Left Atrial Appendage Closure: The OCEAN‐LAAC Registry Open
Background The impact of peridevice leak (PDL) at device implantation on clinical outcomes after percutaneous left atrial appendage closure (LAAC) is unknown. This study aimed to investigate the association between PDL and clinical outcome…
View article: Shortening and optimization of MEF2C and GATA4 promote cardiac reprogramming
Shortening and optimization of MEF2C and GATA4 promote cardiac reprogramming Open
Direct cardiac reprogramming is a ground-breaking approach in regenerative medicine. Overexpression of three cardiac transcription factors (TFs), MEF2C, GATA4, and TBX5 (MGT), reprograms fibroblasts into induced cardiomyocytes (iCMs). Howe…
View article: Inhibition of Scarb1 on Endothelial Cells Attenuates Pressure Overload-Induced Heart Failure Progression
Inhibition of Scarb1 on Endothelial Cells Attenuates Pressure Overload-Induced Heart Failure Progression Open
Inappropriate endothelial cell (EC) interactions contribute to heart failure; however, their precise mechanisms remain poorly understood. This study investigated EC-fibroblast interactions mediated by Scarb1 using single-cell RNA-sequencin…
View article: Echocardiographic Changes With Mavacamten in Nonobstructive Hypertrophic Cardiomyopathy
Echocardiographic Changes With Mavacamten in Nonobstructive Hypertrophic Cardiomyopathy Open
View article: CD300a immunoreceptor regulates ischemic tissue damage and adverse remodeling in the mouse heart and kidney
CD300a immunoreceptor regulates ischemic tissue damage and adverse remodeling in the mouse heart and kidney Open
Acute ischemic organ diseases such as acute myocardial infarction and acute kidney injury often result in irreversible tissue damage and progress to chronic heart failure (CHF) and chronic kidney disease (CKD), respectively. However, the m…
View article: Induced lung epithelial-like cells derived by direct reprogramming rescue influenza virus-induced lung injury in mice
Induced lung epithelial-like cells derived by direct reprogramming rescue influenza virus-induced lung injury in mice Open
We recently reported that a combination of four transcription factors (Nkx2-1, Foxa1, Foxa2, and Gata6) directly reprograms mouse embryonic fibroblasts (MEFs) into differentiated self-renewable alveolar epithelial-like cells in a serum-fre…
View article: Patient-centered medical tools for sustained motivation in cardiac rehabilitation of patients with heart failure: protocol of a multicenter randomized controlled trial (EXERCISE-HF trial)
Patient-centered medical tools for sustained motivation in cardiac rehabilitation of patients with heart failure: protocol of a multicenter randomized controlled trial (EXERCISE-HF trial) Open
View article: Risk-Stratified Prognostic Implications of Contrast-Associated Acute Kidney Injury After Percutaneous Coronary Intervention
Risk-Stratified Prognostic Implications of Contrast-Associated Acute Kidney Injury After Percutaneous Coronary Intervention Open
CA-AKI was associated with long-term outcomes across all AKI risk profiles in PCI patients, underscoring the importance of interventions to reduce periprocedural CA-AKI.
View article: Direct reprogramming of mouse fibroblasts into self-renewable alveolar epithelial-like cells
Direct reprogramming of mouse fibroblasts into self-renewable alveolar epithelial-like cells Open
Direct reprogramming is a breakthrough technology that can alter the fate of cells without the passage of stem cells. However, direct reprogramming of somatic cells into pulmonary alveolar epithelial cells has not yet been achieved. Here, …
View article: Bleeding risk in East Asian patients with atrial fibrillation: Validation of the DOAC score in a Japanese multicenter registry
Bleeding risk in East Asian patients with atrial fibrillation: Validation of the DOAC score in a Japanese multicenter registry Open
The DOAC score proved valuable for long-term bleeding risk assessment in Japanese patients with AF, with enhanced performance through antiplatelet stratification. These findings support its implementation in East Asian populations for indi…
View article: Serine synthesis pathway regulates cardiac differentiation from human pluripotent stem cells
Serine synthesis pathway regulates cardiac differentiation from human pluripotent stem cells Open
Human pluripotent stem cell-derived cardiomyocyte (hPSC-CM) differentiation can improve using chemical compounds which mimic early heart development. However, variations in hPSC-CM differentiation efficiency and its poor reproducibility ha…
View article: Differences between 2 cryoballoon systems in achieving successful pulmonary vein isolation in patients with challenging anatomies
Differences between 2 cryoballoon systems in achieving successful pulmonary vein isolation in patients with challenging anatomies Open
The touch-up RFA rate for the RIPV was significantly lower in the POLAR group than in the AFA-Pro group, with a particularly pronounced difference for inferiorly oriented RIPVs.
View article: 71917 | Discordance Between Echocardiographic and Invasive Gradients After TAVI: Potential Contribution of Device-Level Pressure Recovery
71917 | Discordance Between Echocardiographic and Invasive Gradients After TAVI: Potential Contribution of Device-Level Pressure Recovery Open
View article: Slow–fast atrioventricular nodal reentrant tachycardia mimicking junctional tachycardia following atrial extrastimulation
Slow–fast atrioventricular nodal reentrant tachycardia mimicking junctional tachycardia following atrial extrastimulation Open
Intracardiac electrocardiograms were recorded during a narrow QRS supraventricular tachycardia following atrial extrastimulation. What is the mechanism?
View article: Dual impact of anaemia and chronic kidney disease on postpercutaneous coronary intervention outcomes: insights from the Japanese nationwide registry
Dual impact of anaemia and chronic kidney disease on postpercutaneous coronary intervention outcomes: insights from the Japanese nationwide registry Open
Background Anaemia and chronic kidney disease (CKD) are both established risk factors for bleeding events after percutaneous coronary intervention (PCI). These conditions often coexist; however, previous assessments of these factors indivi…
View article: Exercise hemodynamic evaluation in the management of dasatinib-related pulmonary arterial hypertension: a case report
Exercise hemodynamic evaluation in the management of dasatinib-related pulmonary arterial hypertension: a case report Open
View article: Association of a Left Atrial Diverticulum with Adverse Events During Catheter Ablation for Atrial Fibrillation
Association of a Left Atrial Diverticulum with Adverse Events During Catheter Ablation for Atrial Fibrillation Open
Background/Objectives: Left atrial diverticula (LADs) have been reported to potentially be associated with arrhythmic substrates, thromboembolic events, and complications during catheter ablation for atrial fibrillation (AF), but their cli…
View article: Contemporary clinical characteristics and management patterns in hypertrophic cardiomyopathy: insights from baseline enrolment data in a nationwide prospective Japanese registry
Contemporary clinical characteristics and management patterns in hypertrophic cardiomyopathy: insights from baseline enrolment data in a nationwide prospective Japanese registry Open
Background The Japanese Hypertrophic Cardiomyopathy Registry Study was designed to provide comprehensive, real-world insights into the clinical characteristics and management of hypertrophic cardiomyopathy (HCM) in Japan. Methods This mult…
View article: Individualized prediction of atrial fibrillation onset risk based on lifelogs
Individualized prediction of atrial fibrillation onset risk based on lifelogs Open
View article: Long‐Term Impact of Early Subclinical Leaflet Thrombosis After Transcatheter Aortic Valve Implantation
Long‐Term Impact of Early Subclinical Leaflet Thrombosis After Transcatheter Aortic Valve Implantation Open
Background Hypoattenuated leaflet thickening (HALT) after transcatheter aortic valve implantation (TAVI) detected on multidetector computed tomography (MDCT) is considered leaflet thrombosis. However, its impact on long‐term clinical outco…
View article: Clinical outcomes, hemodynamics, and leaflet thrombosis following transcatheter aortic valve replacement with novel intra‐annular devices
Clinical outcomes, hemodynamics, and leaflet thrombosis following transcatheter aortic valve replacement with novel intra‐annular devices Open
Background The indication of transcatheter aortic valve replacement (TAVR) is becoming more prevalent among younger and lower‐risk patients. However, data on the latest intra‐annular TAVR devices are limited. This study aims to compare the…
View article: Ischemic Stroke Complicated by Acute Decompensated Heart Failure and Its Association with Hemoglobin Levels
Ischemic Stroke Complicated by Acute Decompensated Heart Failure and Its Association with Hemoglobin Levels Open
Background Ischemic stroke (IS) is a serious complication in heart failure, particularly following hospitalization for acute decompensated heart failure (ADHF). However, its actual incidence during the acute and stable treatment phases rem…
View article: Characteristics of Sudden Cardiac Arrest in Young Athletes: A Web‐Based Survey of Athletes in Japanese College Sports
Characteristics of Sudden Cardiac Arrest in Young Athletes: A Web‐Based Survey of Athletes in Japanese College Sports Open
Background Sudden death in young athletes is a serious concern, and appropriate, noninvasive, and easily implementable screening of at‐risk individuals is imperative. Objectives This study aimed to identify potential risk factors associate…
View article: Use of 4D Flow CMR to diagnose the cause of desaturation in a 35-year-old male patient with a classic Fontan circulation
Use of 4D Flow CMR to diagnose the cause of desaturation in a 35-year-old male patient with a classic Fontan circulation Open