Masashi Akiya
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View article: Causes of Varied Internal Echo Patterns in Ultrasound Imaging of Breast Lymphoma
Causes of Varied Internal Echo Patterns in Ultrasound Imaging of Breast Lymphoma Open
Background Ultrasound (US) imaging of breast lymphoma often reveals a variety of internal echo patterns, making differentiation from breast cancer challenging. This study aimed to correlate pathological findings with US imaging features of…
View article: A Case of Local Resection of Secondary Perianal Paget Disease Appearing during "Watch and Wait" Management of Locally Advanced Rectal Cancer after Preoperative Chemoradiotherapy
A Case of Local Resection of Secondary Perianal Paget Disease Appearing during "Watch and Wait" Management of Locally Advanced Rectal Cancer after Preoperative Chemoradiotherapy Open
A 78-year-old woman was diagnosed with lower rectal cancer extending to the dentate line. She underwent preoperative chemoradiotherapy, which resulted in tumor shrinkage and clinical complete response (cCR), leading to the implementation o…
View article: An autopsy case of TAFRO syndrome with membranoproliferative glomerulonephritis-like lesions
An autopsy case of TAFRO syndrome with membranoproliferative glomerulonephritis-like lesions Open
View article: Issue Information ‐ Ed Board
Issue Information ‐ Ed Board Open
View article: A Patient who Underwent Endoscopic Submucosal Dissection for a Submucosal Tumor Arising in the Cecum
A Patient who Underwent Endoscopic Submucosal Dissection for a Submucosal Tumor Arising in the Cecum Open
The patient was a 45-year-old man who had positive results of a fecal occult blood test on a medical examination. A colonoscopic examination revealed a submucosal tumor measuring 7 mm in diameter in the cecum. Colorectal endoscopic submuco…
View article: ALK signaling cascade confers multiple advantages to glioblastoma cells through neovascularization and cell proliferation
ALK signaling cascade confers multiple advantages to glioblastoma cells through neovascularization and cell proliferation Open
Anaplastic lymphoma kinase (ALK), which is a receptor tyrosine kinase, is essentially and transiently expressed in the developing nervous system. Here we examined the functional role of the ALK gene in glioblastomas (GBMs). In clinical sam…
View article: Identification of LEFTY as a molecular marker for ovarian clear cell carcinoma
Identification of LEFTY as a molecular marker for ovarian clear cell carcinoma Open
To identify proteins involved in ovarian clear cell carcinoma (OCCCa), shotgun proteomics analysis was applied using formalin-fixed and paraffin-embedded samples of ovarian carcinoma. Analysis of 1521 proteins revealed that 52 were differe…
View article: Functional role of ALK-related signal cascades on modulation of epithelial-mesenchymal transition and apoptosis in uterine carcinosarcoma
Functional role of ALK-related signal cascades on modulation of epithelial-mesenchymal transition and apoptosis in uterine carcinosarcoma Open
View article: The role of FilGAP, a Rac‐specific Rho‐GTPase‐activating protein, in tumor progression and behavior of astrocytomas
The role of FilGAP, a Rac‐specific Rho‐GTPase‐activating protein, in tumor progression and behavior of astrocytomas Open
Fil GAP , a Rac‐specific Rho‐ GTP ase‐activating protein ( GAP ), acts as a mediator of Rho/ ROCK ‐dependent amoeboid movement, and its knockdown results in Rac‐driven mesenchymal morphology. Herein, we focused on the possible roles of Fil…
View article: Cooperation of Sox4 with β-catenin/p300 complex in transcriptional regulation of the Slug gene during divergent sarcomatous differentiation in uterine carcinosarcoma
Cooperation of Sox4 with β-catenin/p300 complex in transcriptional regulation of the Slug gene during divergent sarcomatous differentiation in uterine carcinosarcoma Open
View article: Additional file 1: Figure S1. of Cooperation of Sox4 with β-catenin/p300 complex in transcriptional regulation of the Slug gene during divergent sarcomatous differentiation in uterine carcinosarcoma
Additional file 1: Figure S1. of Cooperation of Sox4 with β-catenin/p300 complex in transcriptional regulation of the Slug gene during divergent sarcomatous differentiation in uterine carcinosarcoma Open
(A) Ishikawa (Ish) cells were transfected with Sox4, Sox7, and Sox9 reporter constructs, together with either Sox4, Sox7, or Sox9. Relative activity was determined based on arbitrary light units of luciferase activity normalized to pRL-TK …