Masashi Fukayama
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View article: Proteomic Signatures Involved in Cardiac Recovery After Mechanical Unloading
Proteomic Signatures Involved in Cardiac Recovery After Mechanical Unloading Open
View article: A Case of Anal Metastasis from Rectal Cancer
A Case of Anal Metastasis from Rectal Cancer Open
View article: Expression patterns of HNF4α, TTF-1, and SMARCA4 in lung adenocarcinomas: impacts on clinicopathological and genetic features
Expression patterns of HNF4α, TTF-1, and SMARCA4 in lung adenocarcinomas: impacts on clinicopathological and genetic features Open
View article: A Case of Strangulated Cholecystitis Caused by a String
A Case of Strangulated Cholecystitis Caused by a String Open
症例は76歳の女性で，朝からの右季肋部痛と嘔気を主訴に近医を受診した．処方された内服薬を服用したが改善傾向がないため，当院に救急搬送された．腹部診察所見では右季肋部に圧痛を認めた．来院時検査所見では特記すべき異常所見を認めなかった．腹部造影CTでは胆囊は頸部と体部の移行部付近で狭窄しており，腫大した底部側胆囊では壁肥厚と造影効果の減弱を認めた．以上の所見から，胆囊捻転症と診断し，緊急腹腔鏡下胆囊摘出術を施行した．術中所見では胆囊は腹壁から肝表面へ繋がる索状物で絞扼されており…
View article: Integrated environmental, lifestyle, and epigenetic risk prediction of primary gastric neoplasia using the longitudinally monitored cohorts
Integrated environmental, lifestyle, and epigenetic risk prediction of primary gastric neoplasia using the longitudinally monitored cohorts Open
View article: Domain Adaptive Multiple Instance Learning for Instance-level Prediction of Pathological Images
Domain Adaptive Multiple Instance Learning for Instance-level Prediction of Pathological Images Open
Pathological image analysis is an important process for detecting abnormalities such as cancer from cell images. However, since the image size is generally very large, the cost of providing detailed annotations is high, which makes it diff…
View article: Supplementary Tables S1- S6 from Distinct Chemopreventive Effects of Aspirin in Diffuse and Intestinal-Type Gastric Cancer
Supplementary Tables S1- S6 from Distinct Chemopreventive Effects of Aspirin in Diffuse and Intestinal-Type Gastric Cancer Open
Supplementary Table 1. Characteristics of gastric cancer patients. Supplementary Table 2. Gastric cancer location, TNM staging in propensity score-matched patients with aspirin. Supplementary Table 3. Associations between the duration of a…
View article: Supplementary Tables S1- S6 from Distinct Chemopreventive Effects of Aspirin in Diffuse and Intestinal-Type Gastric Cancer
Supplementary Tables S1- S6 from Distinct Chemopreventive Effects of Aspirin in Diffuse and Intestinal-Type Gastric Cancer Open
Supplementary Table 1. Characteristics of gastric cancer patients. Supplementary Table 2. Gastric cancer location, TNM staging in propensity score-matched patients with aspirin. Supplementary Table 3. Associations between the duration of a…
View article: Data from Distinct Chemopreventive Effects of Aspirin in Diffuse and Intestinal-Type Gastric Cancer
Data from Distinct Chemopreventive Effects of Aspirin in Diffuse and Intestinal-Type Gastric Cancer Open
Introduction: Although aspirin/NSAIDs may have potential preventive effects on several cancers, it remains unclear on gastric cancer. The purpose of this study is to compare the risk of developing gastric cancer and the histologic c…
View article: Data from Distinct Chemopreventive Effects of Aspirin in Diffuse and Intestinal-Type Gastric Cancer
Data from Distinct Chemopreventive Effects of Aspirin in Diffuse and Intestinal-Type Gastric Cancer Open
Introduction: Although aspirin/NSAIDs may have potential preventive effects on several cancers, it remains unclear on gastric cancer. The purpose of this study is to compare the risk of developing gastric cancer and the histologic c…
View article: Supplementary Tables from Fusion Kinases Identified by Genomic Analyses of Sporadic Microsatellite Instability–High Colorectal Cancers
Supplementary Tables from Fusion Kinases Identified by Genomic Analyses of Sporadic Microsatellite Instability–High Colorectal Cancers Open
Supplementary Tables S1-S12: Supplementary Table S1: Primer sequences used in this study. Supplementary Table S2: Clinical information of tumours analysed in the present study. Supplementary Table S3: Patients' characteristics. Supplementa…
View article: Supplementary Figures from Fusion Kinases Identified by Genomic Analyses of Sporadic Microsatellite Instability–High Colorectal Cancers
Supplementary Figures from Fusion Kinases Identified by Genomic Analyses of Sporadic Microsatellite Instability–High Colorectal Cancers Open
Supplementary Figures S1-S10: Supplementary Figure S1: Clustering of microsatellite instability-high colorectal cancers with promoter DNA methylation analysis. Supplementary Figure S2: Methylation status of CpG dinucleotides in each patien…
View article: Supplementary Tables from Fusion Kinases Identified by Genomic Analyses of Sporadic Microsatellite Instability–High Colorectal Cancers
Supplementary Tables from Fusion Kinases Identified by Genomic Analyses of Sporadic Microsatellite Instability–High Colorectal Cancers Open
Supplementary Tables S1-S12: Supplementary Table S1: Primer sequences used in this study. Supplementary Table S2: Clinical information of tumours analysed in the present study. Supplementary Table S3: Patients' characteristics. Supplementa…
View article: Data from Fusion Kinases Identified by Genomic Analyses of Sporadic Microsatellite Instability–High Colorectal Cancers
Data from Fusion Kinases Identified by Genomic Analyses of Sporadic Microsatellite Instability–High Colorectal Cancers Open
Purpose:Colorectal cancers with microsatellite instability–high (MSI-H) status, due to mismatch repair deficiency, are associated with poor patient outcomes after relapse. We aimed to identify novel therapeutic targets for them.Experimenta…
View article: Data from Fusion Kinases Identified by Genomic Analyses of Sporadic Microsatellite Instability–High Colorectal Cancers
Data from Fusion Kinases Identified by Genomic Analyses of Sporadic Microsatellite Instability–High Colorectal Cancers Open
Purpose:Colorectal cancers with microsatellite instability–high (MSI-H) status, due to mismatch repair deficiency, are associated with poor patient outcomes after relapse. We aimed to identify novel therapeutic targets for them.Experimenta…
View article: Supplementary Figures from Fusion Kinases Identified by Genomic Analyses of Sporadic Microsatellite Instability–High Colorectal Cancers
Supplementary Figures from Fusion Kinases Identified by Genomic Analyses of Sporadic Microsatellite Instability–High Colorectal Cancers Open
Supplementary Figures S1-S10: Supplementary Figure S1: Clustering of microsatellite instability-high colorectal cancers with promoter DNA methylation analysis. Supplementary Figure S2: Methylation status of CpG dinucleotides in each patien…
View article: Data from KLF5 Regulates the Integrity and Oncogenicity of Intestinal Stem Cells
Data from KLF5 Regulates the Integrity and Oncogenicity of Intestinal Stem Cells Open
The intestinal epithelium maintains homeostasis by a self-renewal process involving resident stem cells, including Lgr5+ crypt-base columnar cells, but core mechanisms and their contributions to intestinal cancer are not fully d…
View article: Supplementary Figure 2 from KLF5 Regulates the Integrity and Oncogenicity of Intestinal Stem Cells
Supplementary Figure 2 from KLF5 Regulates the Integrity and Oncogenicity of Intestinal Stem Cells Open
PDF file - 123KB, mRNA expression signal intensities in stem cells of the duodenum of Lgr5 Cre+ Klf5flox/flox mice without Klf5 deletion (x-axis, log) and Lgr5 Cre+ Klf5delta/delta mice (with Klf5 2 deletion) (y-axis, log).
View article: Supplementary Figure Legends from KLF5 Regulates the Integrity and Oncogenicity of Intestinal Stem Cells
Supplementary Figure Legends from KLF5 Regulates the Integrity and Oncogenicity of Intestinal Stem Cells Open
PDF file - 107KB
View article: Supplementary Figure Legends from KLF5 Regulates the Integrity and Oncogenicity of Intestinal Stem Cells
Supplementary Figure Legends from KLF5 Regulates the Integrity and Oncogenicity of Intestinal Stem Cells Open
PDF file - 107KB
View article: Data from Classification of Epstein–Barr Virus–Positive Gastric Cancers by Definition of DNA Methylation Epigenotypes
Data from Classification of Epstein–Barr Virus–Positive Gastric Cancers by Definition of DNA Methylation Epigenotypes Open
Epstein–Barr virus (EBV) is associated with Burkitt lymphoma, nasopharyngeal carcinoma, opportunistic lymphomas in immunocompromised hosts, and a fraction of gastric cancers. Aberrant promoter methylation accompanies human gastric carcinog…
View article: Supplementary Figure 1 from KLF5 Regulates the Integrity and Oncogenicity of Intestinal Stem Cells
Supplementary Figure 1 from KLF5 Regulates the Integrity and Oncogenicity of Intestinal Stem Cells Open
PDF file - 674KB, Experimental design for the sorting of stem cells and TA cells from the duodenum of Lgr5-GFP-IRES-CreERT mice (Lgr5 Cre+ Catnb+/lox(ex3) Klf5flox/flox, Lgr5 Cre+ Catnb+/lox(ex3) Klf5+/+, and Lgr5 Cre+ Klf5flox/flox) for m…
View article: Supplementary Figure 4 from KLF5 Regulates the Integrity and Oncogenicity of Intestinal Stem Cells
Supplementary Figure 4 from KLF5 Regulates the Integrity and Oncogenicity of Intestinal Stem Cells Open
PDF file - 139KB, mRNA expression signal intensities in stem cells from the duodenum of Lgr5 Cre+ Catnblox(deltaex3) Klf5+/+ mice (x-axis, log) and Lgr5 Cre+ Catnblox(deltaex3) Klf5delta/delta mice (yaxis, log).
View article: Supplementary Figure 1 from KLF5 Regulates the Integrity and Oncogenicity of Intestinal Stem Cells
Supplementary Figure 1 from KLF5 Regulates the Integrity and Oncogenicity of Intestinal Stem Cells Open
PDF file - 674KB, Experimental design for the sorting of stem cells and TA cells from the duodenum of Lgr5-GFP-IRES-CreERT mice (Lgr5 Cre+ Catnb+/lox(ex3) Klf5flox/flox, Lgr5 Cre+ Catnb+/lox(ex3) Klf5+/+, and Lgr5 Cre+ Klf5flox/flox) for m…
View article: Supplementary Tables 1 - 18 from KLF5 Regulates the Integrity and Oncogenicity of Intestinal Stem Cells
Supplementary Tables 1 - 18 from KLF5 Regulates the Integrity and Oncogenicity of Intestinal Stem Cells Open
XLS file - 1363KB, Supplementary Table 1. Genes downregulated following the inducible deletion of Klf5 in the duodenal stem cells of Lgr5-EGFP-ires-CreERT2 Catnblox(deltaex3) Klfflox/flox mice, compared with Lgr5-EGFPires-CreERT2 atnblox(d…
View article: Supplementary Methods, Tables 1-5, Figures 1-4 from Classification of Epstein–Barr Virus–Positive Gastric Cancers by Definition of DNA Methylation Epigenotypes
Supplementary Methods, Tables 1-5, Figures 1-4 from Classification of Epstein–Barr Virus–Positive Gastric Cancers by Definition of DNA Methylation Epigenotypes Open
PDF file - 769K
View article: Supplementary Tables 1 - 18 from KLF5 Regulates the Integrity and Oncogenicity of Intestinal Stem Cells
Supplementary Tables 1 - 18 from KLF5 Regulates the Integrity and Oncogenicity of Intestinal Stem Cells Open
XLS file - 1363KB, Supplementary Table 1. Genes downregulated following the inducible deletion of Klf5 in the duodenal stem cells of Lgr5-EGFP-ires-CreERT2 Catnblox(deltaex3) Klfflox/flox mice, compared with Lgr5-EGFPires-CreERT2 atnblox(d…
View article: Supplementary Figure 4 from KLF5 Regulates the Integrity and Oncogenicity of Intestinal Stem Cells
Supplementary Figure 4 from KLF5 Regulates the Integrity and Oncogenicity of Intestinal Stem Cells Open
PDF file - 139KB, mRNA expression signal intensities in stem cells from the duodenum of Lgr5 Cre+ Catnblox(deltaex3) Klf5+/+ mice (x-axis, log) and Lgr5 Cre+ Catnblox(deltaex3) Klf5delta/delta mice (yaxis, log).
View article: Supplementary Table 1 from Activation of DNA Methyltransferase 1 by EBV Latent Membrane Protein 2A Leads to Promoter Hypermethylation of <i>PTEN</i> Gene in Gastric Carcinoma
Supplementary Table 1 from Activation of DNA Methyltransferase 1 by EBV Latent Membrane Protein 2A Leads to Promoter Hypermethylation of <i>PTEN</i> Gene in Gastric Carcinoma Open
Supplementary Table 1 from Activation of DNA Methyltransferase 1 by EBV Latent Membrane Protein 2A Leads to Promoter Hypermethylation of PTEN Gene in Gastric Carcinoma
View article: Data from Classification of Epstein–Barr Virus–Positive Gastric Cancers by Definition of DNA Methylation Epigenotypes
Data from Classification of Epstein–Barr Virus–Positive Gastric Cancers by Definition of DNA Methylation Epigenotypes Open
Epstein–Barr virus (EBV) is associated with Burkitt lymphoma, nasopharyngeal carcinoma, opportunistic lymphomas in immunocompromised hosts, and a fraction of gastric cancers. Aberrant promoter methylation accompanies human gastric carcinog…