Masataka Sugimoto
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View article: Associations between serum pigment epithelium-derived factor and physical performance in older women: The Otassha study
Associations between serum pigment epithelium-derived factor and physical performance in older women: The Otassha study Open
Pigment epithelium-derived factor (PEDF) contributes to the beneficial effects of exercise by suppressing cellular senescence in multiple organs. Its expression declines in the skeletal muscle of aged animals, suggesting a role in age-rela…
View article: Senolytic potential of shea-derived amyrins in senescent fibroblasts
Senolytic potential of shea-derived amyrins in senescent fibroblasts Open
Senescent cells contribute to tissue dysfunction and the progression of age-related diseases. Senolytic therapies, which selectively eliminate these cells, have demonstrated beneficial effects in preclinical models by restoring tissue func…
View article: Role of Dietary Ceramide 2-Aminoethylphosphonate on Aberrant Crypt Foci Formation and Colon Inflammation in 1,2-Dimethylhydrazine-Treated Mice: A Comparison with the Role of Sphingomyelin
Role of Dietary Ceramide 2-Aminoethylphosphonate on Aberrant Crypt Foci Formation and Colon Inflammation in 1,2-Dimethylhydrazine-Treated Mice: A Comparison with the Role of Sphingomyelin Open
Background: Ceramide 2-aminoethylphosphonate (CAEP), a major sphingolipid class in mollusks, possesses unique structures that are not observed in other sphingolipids. CAEP has a carbon–phosphorus bond and unusual long-chain bases (LCBs). C…
View article: Roles of pigment epithelium-derived factor in exercise-induced suppression of senescence and its impact on lung pathology in mice
Roles of pigment epithelium-derived factor in exercise-induced suppression of senescence and its impact on lung pathology in mice Open
Senescent cells contribute to tissue aging and underlie the pathology of chronic diseases. The benefits of eliminating senescent cells have been demonstrated in several disease models, and the efficacy of senolytic drugs is currently being…
View article: Supplementary Figure 6 from ARF Suppresses Tumor Angiogenesis through Translational Control of <i>VEGFA</i> mRNA
Supplementary Figure 6 from ARF Suppresses Tumor Angiogenesis through Translational Control of <i>VEGFA</i> mRNA Open
Supplementary Figure 6 from ARF Suppresses Tumor Angiogenesis through Translational Control of VEGFA mRNA
View article: Data from ARF Suppresses Tumor Angiogenesis through Translational Control of <i>VEGFA</i> mRNA
Data from ARF Suppresses Tumor Angiogenesis through Translational Control of <i>VEGFA</i> mRNA Open
Vascular endothelial growth factor A (VEGFA) is a specific mitogen for vascular endothelial cells that plays a critical role in cancer neoangiogenesis. Here, we report that the nucleolar tumor suppressor p19ARF suppresses VEGFA expression,…
View article: Supplementary Figure 6 from ARF Suppresses Tumor Angiogenesis through Translational Control of <i>VEGFA</i> mRNA
Supplementary Figure 6 from ARF Suppresses Tumor Angiogenesis through Translational Control of <i>VEGFA</i> mRNA Open
Supplementary Figure 6 from ARF Suppresses Tumor Angiogenesis through Translational Control of VEGFA mRNA
View article: Supplementary Figure Legends 1-5 from ARF Suppresses Tumor Angiogenesis through Translational Control of <i>VEGFA</i> mRNA
Supplementary Figure Legends 1-5 from ARF Suppresses Tumor Angiogenesis through Translational Control of <i>VEGFA</i> mRNA Open
Supplementary Figure Legends 1-5 from ARF Suppresses Tumor Angiogenesis through Translational Control of VEGFA mRNA
View article: Supplementary Figure 3 from ARF Suppresses Tumor Angiogenesis through Translational Control of <i>VEGFA</i> mRNA
Supplementary Figure 3 from ARF Suppresses Tumor Angiogenesis through Translational Control of <i>VEGFA</i> mRNA Open
Supplementary Figure 3 from ARF Suppresses Tumor Angiogenesis through Translational Control of VEGFA mRNA
View article: Supplementary Figure 4 from ARF Suppresses Tumor Angiogenesis through Translational Control of <i>VEGFA</i> mRNA
Supplementary Figure 4 from ARF Suppresses Tumor Angiogenesis through Translational Control of <i>VEGFA</i> mRNA Open
Supplementary Figure 4 from ARF Suppresses Tumor Angiogenesis through Translational Control of VEGFA mRNA
View article: Supplementary Figure 1 from ARF Suppresses Tumor Angiogenesis through Translational Control of <i>VEGFA</i> mRNA
Supplementary Figure 1 from ARF Suppresses Tumor Angiogenesis through Translational Control of <i>VEGFA</i> mRNA Open
Supplementary Figure 1 from ARF Suppresses Tumor Angiogenesis through Translational Control of VEGFA mRNA
View article: Supplementary Figure 5 from ARF Suppresses Tumor Angiogenesis through Translational Control of <i>VEGFA</i> mRNA
Supplementary Figure 5 from ARF Suppresses Tumor Angiogenesis through Translational Control of <i>VEGFA</i> mRNA Open
Supplementary Figure 5 from ARF Suppresses Tumor Angiogenesis through Translational Control of VEGFA mRNA
View article: Data from ARF Suppresses Tumor Angiogenesis through Translational Control of <i>VEGFA</i> mRNA
Data from ARF Suppresses Tumor Angiogenesis through Translational Control of <i>VEGFA</i> mRNA Open
Vascular endothelial growth factor A (VEGFA) is a specific mitogen for vascular endothelial cells that plays a critical role in cancer neoangiogenesis. Here, we report that the nucleolar tumor suppressor p19ARF suppresses VEGFA expression,…
View article: Supplementary Figure 2 from ARF Suppresses Tumor Angiogenesis through Translational Control of <i>VEGFA</i> mRNA
Supplementary Figure 2 from ARF Suppresses Tumor Angiogenesis through Translational Control of <i>VEGFA</i> mRNA Open
Supplementary Figure 2 from ARF Suppresses Tumor Angiogenesis through Translational Control of VEGFA mRNA
View article: Supplementary Figure 4 from ARF Suppresses Tumor Angiogenesis through Translational Control of <i>VEGFA</i> mRNA
Supplementary Figure 4 from ARF Suppresses Tumor Angiogenesis through Translational Control of <i>VEGFA</i> mRNA Open
Supplementary Figure 4 from ARF Suppresses Tumor Angiogenesis through Translational Control of VEGFA mRNA
View article: Supplementary Figure 2 from ARF Suppresses Tumor Angiogenesis through Translational Control of <i>VEGFA</i> mRNA
Supplementary Figure 2 from ARF Suppresses Tumor Angiogenesis through Translational Control of <i>VEGFA</i> mRNA Open
Supplementary Figure 2 from ARF Suppresses Tumor Angiogenesis through Translational Control of VEGFA mRNA
View article: Supplementary Figure 5 from ARF Suppresses Tumor Angiogenesis through Translational Control of <i>VEGFA</i> mRNA
Supplementary Figure 5 from ARF Suppresses Tumor Angiogenesis through Translational Control of <i>VEGFA</i> mRNA Open
Supplementary Figure 5 from ARF Suppresses Tumor Angiogenesis through Translational Control of VEGFA mRNA
View article: Supplementary Figure 1 from ARF Suppresses Tumor Angiogenesis through Translational Control of <i>VEGFA</i> mRNA
Supplementary Figure 1 from ARF Suppresses Tumor Angiogenesis through Translational Control of <i>VEGFA</i> mRNA Open
Supplementary Figure 1 from ARF Suppresses Tumor Angiogenesis through Translational Control of VEGFA mRNA
View article: Supplementary Figure Legends 1-5 from ARF Suppresses Tumor Angiogenesis through Translational Control of <i>VEGFA</i> mRNA
Supplementary Figure Legends 1-5 from ARF Suppresses Tumor Angiogenesis through Translational Control of <i>VEGFA</i> mRNA Open
Supplementary Figure Legends 1-5 from ARF Suppresses Tumor Angiogenesis through Translational Control of VEGFA mRNA
View article: Supplementary Figure 3 from ARF Suppresses Tumor Angiogenesis through Translational Control of <i>VEGFA</i> mRNA
Supplementary Figure 3 from ARF Suppresses Tumor Angiogenesis through Translational Control of <i>VEGFA</i> mRNA Open
Supplementary Figure 3 from ARF Suppresses Tumor Angiogenesis through Translational Control of VEGFA mRNA
View article: Towards a Circular Economy: Study of the Mechanical, Thermal, and Electrical Properties of Recycled Polypropylene and Their Composite Materials
Towards a Circular Economy: Study of the Mechanical, Thermal, and Electrical Properties of Recycled Polypropylene and Their Composite Materials Open
This research focuses on the mechanical properties of polypropylene (PP) blended with recycled PP (rPP) at various concentrations. The rPP can be added at up to 40 wt% into the PP matrix without significantly affecting the mechanical prope…
View article: Age-related changes in lung function in National Center for Geriatrics and Gerontology Aging Farm C57BL/6N mice
Age-related changes in lung function in National Center for Geriatrics and Gerontology Aging Farm C57BL/6N mice Open
Aging is an extremely complex biological process, and various models, from unicellular organisms to mammals, have been used in its research. The mouse is the most widely used model for studying human aging and diseases due to its high homo…
View article: Cellular senescence promotes cancer metastasis by enhancing soluble E-cadherin production
Cellular senescence promotes cancer metastasis by enhancing soluble E-cadherin production Open
Cellular senescence acts as a potent tumor-suppression mechanism in mammals; however, it also promotes tumor progression in a non-cell-autonomous manner. We provided insights into the mechanism underlying senescence-dependent metastatic ca…
View article: Effects of CREG1 on Age-Associated Metabolic Phenotypes and Renal Senescence in Mice
Effects of CREG1 on Age-Associated Metabolic Phenotypes and Renal Senescence in Mice Open
Cellular repressor of E1A-stimulated genes 1 (CREG1) is a secreted glycoprotein that accelerates p16-dependent cellular senescence in vitro. We recently reported the ability of CREG1 to stimulate brown adipogenesis using adipocyte P2-CREG1…
View article: Supplementary Material for: A Questionnaire-Based Survey on the Impact of the COVID-19 Pandemic on Gastrointestinal Endoscopy in Asia
Supplementary Material for: A Questionnaire-Based Survey on the Impact of the COVID-19 Pandemic on Gastrointestinal Endoscopy in Asia Open
Introduction: The COVID-19 outbreak abruptly restricted gastrointestinal (GI) endoscopy services during the first wave of the pandemic. We aimed to assess the impact of COVID-19 on the practice of GI endoscopy in Asian countries. Methods: …
View article: Polymer Gel Fibers Produced by UV-Reactive Electrospinning
Polymer Gel Fibers Produced by UV-Reactive Electrospinning Open
A potentially effective method to prepare fibers of polymer gels with chemically crosslinked structure using ultraviolet (UV)-reactive electrospinning (UV-ES) is demonstrated. The UV-ES method makes sure the polymerization (i. e., gelation…