Explanipedia

Clinical outcomes and prognostic factors of adjuvant radiotherapy for vulvar cancer: a Japanese Gynecologic Oncology Group nationwide survey study Open

Keisuke Tsuchida, Ken Ando, Noriyuki Okonogi, Mayuyo Mori, Masato Nishimura , et al. · 2025

This study aimed to analyze the clinical outcomes and prognostic factors of postoperative adjuvant radiotherapy (RT) for vulvar cancer based on a retrospective Japanese nationwide survey. Data were collected from 108 institutions for patie…

Evaluation of platinum-free interval and chemotherapeutic effect of subsequent platinum-containing chemotherapy in patients with recurrent ovarian cancer initially treated with bevacizumab: SGSG018/Intergroup study Open

Tamaki Tanaka, Kazuhiro Takehara, Tomoka Usami, Masako Ishikawa, Eiji Kondo , et al. · 2025

Development of a scale to assess psychological adjustment in survivors of women's cancers: Reliability and validity Open

Isako Ueta, Hiroko Ota, Miho Ono, Chiemi Onishi, Shingo Asano , et al. · 2025

Kamikihito contributes to visceral fat reduction and appetite suppression in PCOS model rats by increasing OTR and leptin expression in visceral fat Open

Shota Yamamoto, Ryosuke Arakaki, Moeka Arata, Kou Tamura, Hidenori Aoki , et al. · 2025

Polycystic ovary syndrome (PCOS) is an endocrine disorder that causes infertility as well as obesity. Oxytocin (OT), a neuropeptide involved in appetite and fat metabolism, may be therapeutically beneficial for PCOS. Kamikihito (KKT), a tr…

ESTABLISHMENT OF A CENTRALIZED SYSTEM FOR PREOPERATIVE AUTOLOGOUS BLOOD COLLECTION IN TOKUSHIMA UNIVERSITY HOSPITAL -PATIENT CHARACTERISTICS OF VVR AND FUTURE ISSUES- Open

Hirokazu Miki, Tomomi Takimoto, Ryo Takahashi, Erika Tsukuda, Naoki Oda , et al. · 2024

New treatment strategies for uterine sarcoma using secreted frizzled‑related proteins Open

Tomohiro Kagawa, Ayuka Mineda, Tomotaka Nakagawa, Ayaka Shinohara, Ryosuke Arakaki , et al. · 2024

Secreted frizzled-related proteins (SFRPs) are involved in the development of various types of cancer and function by suppressing the Wnt signaling pathway. To elucidate the clinical implications of SFRPs in uterine sarcoma, SFRP expressio…

Expression of SMADs in orthotopic human endometrium, ovarian endometriosis, and endometriotic lesions in a murine model Open

Yuri Kadota, Takeshi Kato, Kana Kasai, Takako Kawakita, Misaki Murayama , et al. · 2024

Activin A promotes the development of endometriotic lesions in a murine model of endometriosis, and the immunohistochemical localization of phosphorylated suppressor of mothers against decapentaplegic homolog 2/3 (pSMAD2/3) complex in endo…

#215 Retrospective re-evaluation of platinum-free interval and chemotherapeutic effect against subsequent platinum-containing chemotherapy in recurrent ovarian cancer patients initially treated by chemotherapy with bevacizumab Open

Tamaki Tanaka, Tomoka Usami, Masako Ishikawa, Eiji Kondo, Masahiro Kagabu , et al. · 2023

Introduction/Background It is concerned that the tumor dormancy effect of bevacizumab might prolong disease-free interval (DFI) regardless of platinum sensitivity, and lead to poorer outcome especially for patients recurrent in partially p…

Supplementary Figures 1-12 from Therapeutic Synergy between microRNA and siRNA in Ovarian Cancer Treatment Open

Masato Nishimura, Eunjung Jung, Maitri Shah, Chunhua Lu, Riccardo Spizzo , et al. · 2023

Supplementary Figures 1-12 - PDF file 897K, Relative expression of miR-520d-3p (miR-520d) and miR-520d-5p (miR-520d*) in ovarian cancer cell lines (Figure S1), Kaplan-Meier curves representing the percent progression-free survival in patie…

Supplementary Figures 1-12 from Therapeutic Synergy between microRNA and siRNA in Ovarian Cancer Treatment Open

Masato Nishimura, Eunjung Jung, Maitri Shah, Chunhua Lu, Riccardo Spizzo , et al. · 2023

Supplementary Figures 1-12 - PDF file 897K, Relative expression of miR-520d-3p (miR-520d) and miR-520d-5p (miR-520d*) in ovarian cancer cell lines (Figure S1), Kaplan-Meier curves representing the percent progression-free survival in patie…

Supplementary Tables 1-2 from Therapeutic Synergy between microRNA and siRNA in Ovarian Cancer Treatment Open

Masato Nishimura, Eunjung Jung, Maitri Shah, Chunhua Lu, Riccardo Spizzo , et al. · 2023

Supplementary Tables 1-2 - PDF file 85K, MicroRNAs significantly associated with overall survival and response to therapy in ovarian cancer patients using TCGA 2009 database (Table S1) and Clinical and bio-pathological features of the 91 M…

Data from Therapeutic Synergy between microRNA and siRNA in Ovarian Cancer Treatment Open

Masato Nishimura, Eunjung Jung, Maitri Shah, Chunhua Lu, Riccardo Spizzo , et al. · 2023

Development of improved RNA interference–based strategies is of utmost clinical importance. Although siRNA-mediated silencing of EphA2, an ovarian cancer oncogene, results in reduction of tumor growth, we present evidence that additional i…

Supplementary Tables 1-2 from Therapeutic Synergy between microRNA and siRNA in Ovarian Cancer Treatment Open

Masato Nishimura, Eunjung Jung, Maitri Shah, Chunhua Lu, Riccardo Spizzo , et al. · 2023

Supplementary Tables 1-2 - PDF file 85K, MicroRNAs significantly associated with overall survival and response to therapy in ovarian cancer patients using TCGA 2009 database (Table S1) and Clinical and bio-pathological features of the 91 M…

Data from Therapeutic Synergy between microRNA and siRNA in Ovarian Cancer Treatment Open

Masato Nishimura, Eunjung Jung, Maitri Shah, Chunhua Lu, Riccardo Spizzo , et al. · 2023

Development of improved RNA interference–based strategies is of utmost clinical importance. Although siRNA-mediated silencing of EphA2, an ovarian cancer oncogene, results in reduction of tumor growth, we present evidence that additional i…

Supplementary Figure 1 from Metronomic Activity of CD44-Targeted Hyaluronic Acid-Paclitaxel in Ovarian Carcinoma Open

Sun Joo Lee, Sukhen C. Ghosh, Hee Dong Han, Rebecca L. Stone, Justin Bottsford-Miller , et al. · 2023

PDF file, 104KB, Effects of MET and MTD HA-TXL therapy on tumor nodules in ovarian cancer models.

Supplementary Figure 1 from Converging Evidence for Efficacy from Parallel EphB4-Targeted Approaches in Ovarian Carcinoma Open

Whitney A. Spannuth, Lingegowda S. Mangala, Rebecca L. Stone, Amy R. Carroll, Masato Nishimura , et al. · 2023

Supplementary Figure 1 from Converging Evidence for Efficacy from Parallel EphB4-Targeted Approaches in Ovarian Carcinoma

Data from Functional Roles of Src and Fgr in Ovarian Carcinoma Open

Hye‐Sun Kim, Hee Dong Han, Guillermo N. Armaiz-Peña, Rebecca L. Stone, Eun Ji Nam , et al. · 2023

Purpose:Src is an attractive target because it is overexpressed in a number of malignancies, including ovarian cancer. However, the effect of Src silencing on other Src family kinases (SFKs) is not known. We hypothesiz…

Data from Functional Roles of Src and Fgr in Ovarian Carcinoma Open

Hye‐Sun Kim, Hee Dong Han, Guillermo N. Armaiz-Peña, Rebecca L. Stone, Eun Ji Nam , et al. · 2023

Purpose:Src is an attractive target because it is overexpressed in a number of malignancies, including ovarian cancer. However, the effect of Src silencing on other Src family kinases (SFKs) is not known. We hypothesiz…

Data from Converging Evidence for Efficacy from Parallel EphB4-Targeted Approaches in Ovarian Carcinoma Open

Whitney A. Spannuth, Lingegowda S. Mangala, Rebecca L. Stone, Amy R. Carroll, Masato Nishimura , et al. · 2023

EphB4 is a transmembrane receptor tyrosine kinase that plays an important role in neural plasticity and angiogenesis. EphB4 is overexpressed in ovarian cancer and is predictive of poor clinical outcome. However, the biological significance…

Supplementary Figure 2 from Metronomic Activity of CD44-Targeted Hyaluronic Acid-Paclitaxel in Ovarian Carcinoma Open

Sun‐Joo Lee, Sukhen C. Ghosh, Hee Dong Han, Rebecca L. Stone, Justin Bottsford-Miller , et al. · 2023

PDF file, 67KB, Effects of HA-TXL MTD and HA-TXL MET on white blood count (WBC)and hemoglobin levels.

Data from Metronomic Activity of CD44-Targeted Hyaluronic Acid-Paclitaxel in Ovarian Carcinoma Open

Sun Joo Lee, Sukhen C. Ghosh, Hee Dong Han, Rebecca L. Stone, Justin Bottsford-Miller , et al. · 2023

Purpose: Most primary human ovarian tumors and peritoneal implants, as well as tumor vascular endothelial cells, express the CD44 family of cell surface proteoglycans, the natural ligand for which is hyaluronic acid. Metronomic dosi…

Supplementary Figure 2 from Metronomic Activity of CD44-Targeted Hyaluronic Acid-Paclitaxel in Ovarian Carcinoma Open

Sun Joo Lee, Sukhen C. Ghosh, Hee Dong Han, Rebecca L. Stone, Justin Bottsford-Miller , et al. · 2023

PDF file, 67KB, Effects of HA-TXL MTD and HA-TXL MET on white blood count (WBC)and hemoglobin levels.

Supplementary Figure 3 from Metronomic Activity of CD44-Targeted Hyaluronic Acid-Paclitaxel in Ovarian Carcinoma Open

Sun‐Joo Lee, Sukhen C. Ghosh, Hee Dong Han, Rebecca L. Stone, Justin Bottsford-Miller , et al. · 2023

PDF file, 366KB, Effects of MET and MTD HA-TXL treatment in the HeyA8-MDR model on biological endpoints.

Supplementary Figures S1-S5 from Functional Roles of Src and Fgr in Ovarian Carcinoma Open

Hye‐Sun Kim, Hee Dong Han, Guillermo N. Armaiz-Peña, Rebecca L. Stone, Eun Ji Nam , et al. · 2023

Supplementary Figures S1-S5.

Supplementary Methods from Metronomic Activity of CD44-Targeted Hyaluronic Acid-Paclitaxel in Ovarian Carcinoma Open

Sun Joo Lee, Sukhen C. Ghosh, Hee Dong Han, Rebecca L. Stone, Justin Bottsford-Miller , et al. · 2023

PDF file, 108KB.