Masayuki Aoyama
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View article: Low Plasma Levels of Soluble Endoglin and Cardiovascular Events in Patients Undergoing Coronary Angiography
Low Plasma Levels of Soluble Endoglin and Cardiovascular Events in Patients Undergoing Coronary Angiography Open
TGF-β is recognized as playing a protective role against atherosclerosis. Endoglin is a receptor for TGF-β, and its expression is upregulated in atherosclerotic plaques. Endoglin is secreted from the cell membrane into the circulation as a…
View article: Association between the Japanese Diet and Coronary Artery Disease in Patients Undergoing Coronary Angiography
Association between the Japanese Diet and Coronary Artery Disease in Patients Undergoing Coronary Angiography Open
Several cohort studies have reported that the Japanese diet is associated with reduced cardiovascular disease mortality. However, the results were not always consistent, and most of those studies conducted dietary surveys around 1990. We i…
View article: Plasma Concentrations of Vinculin versus Talin-1 in Coronary Artery Disease
Plasma Concentrations of Vinculin versus Talin-1 in Coronary Artery Disease Open
Vinculin and talin-1, which are cytoskeletal proteins affecting focal adhesions, were reported to be down-expressed in atherosclerotic lesions. Recently, we reported high concentrations of plasma talin-1 in patients with coronary artery di…
View article: High Plasma Levels of Fortilin in Patients with Coronary Artery Disease
High Plasma Levels of Fortilin in Patients with Coronary Artery Disease Open
Excessive apoptosis is known to be a common feature of atherosclerotic lesions. Fortilin is recognized to have potent antiapoptotic properties. An increased fortilin expression was demonstrated in atherosclerotic lesions, and fortilin knoc…
View article: No Significant Association Between Plasma Endosialin Levels and the Presence or Severity of Coronary Artery Disease
No Significant Association Between Plasma Endosialin Levels and the Presence or Severity of Coronary Artery Disease Open
Plasma endosialin levels in patients with CAD were found to be not higher than in those without CAD and to be not significantly associated with the presence or severity of CAD.
View article: Association between Plasma Follistatin-like Protein 1 Levels and the Presence and Severity of Coronary Artery Disease
Association between Plasma Follistatin-like Protein 1 Levels and the Presence and Severity of Coronary Artery Disease Open
Follistatin-like protein 1 (FSTL1) is a secreted glycoprotein known for its role in inflammation. However, plasma FSTL1 levels in patients with coronary artery disease (CAD) have not been fully elucidated. Thus, in this study, we investiga…
View article: Associations Between Plasma Kinin B1 Receptor Levels and the Presence and Severity of Coronary Artery Disease
Associations Between Plasma Kinin B1 Receptor Levels and the Presence and Severity of Coronary Artery Disease Open
Aim: Kinin B1 receptor (KB1R) was shown to be up-regulated in human carotid atherosclerotic lesions. Serum KB1R levels were also reported to be high in patients with stroke. However, KB1R deficiency increased atherosclerotic lesions. There…
View article: Association between Plasma Sestrin2 Levels and the Presence and Severity of Coronary Artery Disease
Association between Plasma Sestrin2 Levels and the Presence and Severity of Coronary Artery Disease Open
Aims . Atherosclerotic disease, such as coronary artery disease (CAD), is recognized to be associated with inflammation and oxidative stress. We investigated the association between CAD and plasma levels of sestrin2 which is one of the str…
View article: Associations between Green Tea Consumption and Coffee Consumption and the Prevalence of Coronary Artery Disease
Associations between Green Tea Consumption and Coffee Consumption and the Prevalence of Coronary Artery Disease Open
Green tea and coffee contain various bioactive compounds (e.g., polyphenols), and their consumption has been proposed to decrease the risk of cardiovascular diseases. Here, we investigated the associations between the consumption of green …
View article: High Plasma Levels of Soluble Talin-1 in Patients with Coronary Artery Disease
High Plasma Levels of Soluble Talin-1 in Patients with Coronary Artery Disease Open
Aims. Talin-1 is a cytoskeletal protein that binds integrin, thereby leading to integrin activation and affecting focal adhesions. Recently, talin-1 expression was reported to be downregulated in human atherosclerotic plaques. However, blo…
View article: High Plasma Levels of Legumain in Patients with Complex Coronary Lesions
High Plasma Levels of Legumain in Patients with Complex Coronary Lesions Open
Plasma legumain levels were associated with the presence of complex coronary lesions.