Masood Khosravani
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View article: Combination chemotherapy via poloxamer 188 surface-modified PLGA nanoparticles that traverse the blood–brain–barrier in a glioblastoma model
Combination chemotherapy via poloxamer 188 surface-modified PLGA nanoparticles that traverse the blood–brain–barrier in a glioblastoma model Open
The effect of chemotherapy for anti-glioblastoma is limited due to insufficient drug delivery across the blood-brain-barrier. Poloxamer 188-coated nanoparticles can enhance the delivery of nanoparticles across the blood-brain-barrier. This…
View article: Combinatorial chemotherapy via poloxamer 188 surface-modified PLGA nanoparticles that traverse the blood-brain-barrier in a glioblastoma model
Combinatorial chemotherapy via poloxamer 188 surface-modified PLGA nanoparticles that traverse the blood-brain-barrier in a glioblastoma model Open
The effect of anti-glioblastoma therapies is dwindling due to insufficient delivery across the blood-brain-barrier. It has been stated that poloxamer 188-coated nanoparticles are able to circumvent the blood-brain-barrier. Building off of …
View article: PLGA Nanoparticles Loaded with Cinnamon Extract and Coated with PVA/Poloxamer188
PLGA Nanoparticles Loaded with Cinnamon Extract and Coated with PVA/Poloxamer188 Open
Cinnamon extract has received significant attention due to its significant antibacterial, antifungal, antioxidant, and even anti-cancer properties. The purpose of this study was to create cinnamon-extract-loaded PLGA nanoparticles and eval…
View article: Study of in vitro cytotoxic performance of biosynthesized α-Bi2O3 NPs, Mn-doped and Zn-doped Bi2O3 NPs against MCF-7 and HUVEC cell lines
Study of in vitro cytotoxic performance of biosynthesized α-Bi2O3 NPs, Mn-doped and Zn-doped Bi2O3 NPs against MCF-7 and HUVEC cell lines Open
View article: Yogurt fortified with omega‐3 using nanoemulsion containing flaxseed oil: Investigation of physicochemical properties
Yogurt fortified with omega‐3 using nanoemulsion containing flaxseed oil: Investigation of physicochemical properties Open
Flaxseed oil as a natural ingredient has many health benefits due to the rich contents of omega‐3 fatty acids. However, its use in food formulations is limited because of low aqueous solubility, easy oxidation owing to the unsaturated natu…
View article: Preparation of cationized albumin nanoparticles loaded indirubin by high pressure hemogenizer
Preparation of cationized albumin nanoparticles loaded indirubin by high pressure hemogenizer Open
Indirubin can be applied as an anti-cancer drug for inhibition of brain tumors. However, its performance is reduced due to hydrophobicity. In this study, we synthesized cationic human serum albumin (CHSA) nanoparticle by a new hybrid appro…
View article: Preparation of cationized albumin nanoparticles loaded indirubin by high pressure hemogenizer
Preparation of cationized albumin nanoparticles loaded indirubin by high pressure hemogenizer Open
Indirubin can be applied as an anti-cancer drug for inhibition of brain tumors. However, its performance is reduced due to hydrophobicity. In this study, we synthesized cationic human serum albumin (CHSA) nanoparticle by a new hybrid appro…
View article: Paclitaxel/methotrexate co-loaded PLGA nanoparticles in glioblastoma treatment: Formulation development and in vitro antitumor activity evaluation
Paclitaxel/methotrexate co-loaded PLGA nanoparticles in glioblastoma treatment: Formulation development and in vitro antitumor activity evaluation Open
View article: Preparation of curcumin-loaded PLGA nanoparticles and investigation of its cytotoxicity effects on human glioblastoma U87MG cells
Preparation of curcumin-loaded PLGA nanoparticles and investigation of its cytotoxicity effects on human glioblastoma U87MG cells Open
Curcumin, an herbal derivative, could be used as anticancer agent in drug delivery. Due to hydrophobic properties of curcumin, its bioavailability decreases to cancer cells. The aim of this study was to prepare curcumin loaded poly (lactic…
View article: Investigation of Effective Parameters on Size of Paclitaxel Loaded PLGA Nanoparticles
Investigation of Effective Parameters on Size of Paclitaxel Loaded PLGA Nanoparticles Open
Purpose: The size of polymeric nanoparticles is considered as an effective factor in cancer therapy due to enterance into tumor tissue via the EPR effect. The purpose of this work was to investigate the effective parameters o…
View article: Preparation of Methotrexate loaded PLGA nanoparticles coated with PVA and Poloxamer188
Preparation of Methotrexate loaded PLGA nanoparticles coated with PVA and Poloxamer188 Open
Objective(s): Nanoparticles offer an attractive platform for drug delivery through a wide variety of the body's physiological barriers. Furthermore, modification of nanoparticle surface with moeites such as Poloxamer188 ca…
View article: Methotrexate-Loaded PLGA Nanoparticles: Preparation, Characterization and their Cytotoxicity Effect on Human Glioblastoma U87MG Cells
Methotrexate-Loaded PLGA Nanoparticles: Preparation, Characterization and their Cytotoxicity Effect on Human Glioblastoma U87MG Cells Open
The purpose of the current study was to prepare Methotrexate (MTX) loaded Poly Lactic-Co-Glycolic Acid (PLGA) Nanoparticles (NPs) and investigates their toxicity effect on human glioblastoma cells. The influence of different experimental p…
View article: A novel recombinant anti‐epidermal growth factor receptor peptide vaccine capable of active immunization and reduction of tumor volume in a mouse model
A novel recombinant anti‐epidermal growth factor receptor peptide vaccine capable of active immunization and reduction of tumor volume in a mouse model Open
Over‐expression of epidermal growth factor receptor (EGFR) has been reported in a number of human malignancies. Strong expression of this receptor has been associated with poor survival in many such patients. Active immunizations that elic…