Explanipedia

Implementation and Impact of a Patient Blood Management Program in an Urban Community Hospital: An Eight-Year Study Open

Robert Karpinos, Mark T. Friedman, Daniel Lombardi, Y. Li, Valdet Cobaj , et al. · 2025

Purpose: This study evaluates the efficacy of a patient blood management (PBM) initiative in reducing unnecessary red blood cell (RBC) transfusions at a New York City community teaching hospital over eight years (2013–2020). Methods: A ret…

NF-κB-Mediated Disruption of Key Transcription Factors Predisposes Lower Esophageal Squamous Epithelium to Esophageal Adenocarcinoma: a systematic review Open

Ovais Shafi, Aysha B. Khalid, Nfn Aakash, Moeed Ahmad, Akash Shah , et al. · 2025

Objective The objective of this study is to determine how NF-κB-mediated transcriptional disruption of key transcription factors (TP63, SOX2, KLF4, GRHL3, ELF3, TFAP2C, RUNX1, and ZBED2) in esophageal squamous stratified epithelium leads t…

Diaphragmatic hernia Open

Tan Hooi Hooi, Masooma Niazi · 2025

Impact of Patient Blood Management on Red Blood Cell Utilization in an Urban Community Teaching Hospital: A Seven-Year Retrospective Study Open

Ding Wen Wu, Mark T. Friedman, Daniel P. Lombardi, Richard Y. Hwang, Joel Sender , et al. · 2024

Objectives: This study aimed to showcase how implementing a patient blood management (PBM) program effectively cuts unnecessary red blood cell (RBC) transfusions in a New York City urban community teaching hospital. Methods: Analyzing seve…

Impact of Patient Blood Management on Red Blood Cell Utilization in an Urban Community Teaching Hospital: A Seven-Year Retrospective Study Open

Ding Wen Wu, Mark T. Friedman, Daniel Lombardi, Richard Y. Hwang, Joel Sender , et al. · 2024

The study aimed to showcase how implementing a patient blood management (PBM) program effectively cut unnecessary red blood cell (RBC) transfusions in a New York City urban community teaching hospital. Analyzing seven years from 2013 to 20…

Colonic Ganglioneuroma: A Rare Lesion With Extremely Different Presentations and Outcomes in Two Patients Open

Ahmed Baiomi, Hafsa Abbas, Masooma Niazi, Helen Remotti, Myrta Daniel , et al. · 2021

Ganglioneuroma (GN) of the gastrointestinal tract is an extremely rare neuroectodermal tumor. Patients with ganglioneuromas have different presentations depending on the location, extent and size of the lesion. We present two cases of gang…

Atypical Sjögrenʼs Syndrome Initially Presenting as Lymphocytic Interstitial Pneumonitis followed by Immune Thrombocytopenia Open

Maham Mehmood, Abhishrut Jog, Masooma Niazi, Arlene Tieng, Giovanni Franchin · 2021

Background. Sjögrenʼs syndrome is an autoimmune disease characterized primarily by decreased exocrine gland function leading to eye and mouth dryness. Extraglandular manifestations occur less frequently. Case Report. A 74-year-old man with…

Acute Hepatitis in a Yemeni Immigrant Associated with Khat: A “Biological Amphetamine” Carried in Cultures Open

Harish Patel, Kishore Kumar, Rajesh Essrani, Masooma Niazi, Jasbir Makker , et al. · 2021

Viral infections, alcohol, hepatic steatosis, autoimmunity medications and herbal supplements are common etiologies of hepatitis. Khat (Catha Edulis) is a commonly used recreational substance in East African and Middle Eastern countries. K…

Aspiration pneumonia caused by an organic foreign body Open

Haider Ghazanfar, Maneesh Gaddam, Antonio Milian, Masooma Niazi, Ajsza Matela · 2020

Introduction: Aspiration pneumonia is an important cause of morbidity and mortality in the elderly. Foreign body (FB) aspiration although less frequent in adults in comparison to the pediatric population is more prevalent in geriatric pati…

Microthrombi in skin biopsy of a patient with COVID-19 Open

Elona Shehi, Sridhar Chilimuri, Dongmin Shin, Madanmohan Patel, Nisha Ali , et al. · 2020

A Rare Case of Cerebellar Glioblastoma Mimicking Acute Stroke in an Elderly Patient Open

Maleeha Zahid, Laura Yapor, Masooma Niazi, Muhammad Adrish, Ahmad Hanif · 2020

BACKGROUND Glioblastoma (GB) is a common brain tumor that usually presents in the cerebral hemisphere. Very rarely, these tumors can present in the cerebellum. The tumor tends to have a diffuse infiltrative growth that follows the white-ma…

Malignant Epithelioid Neoplasm of the Brain Open

Abhishrut Jog, Diana Ronderos, Asghar Ali, Masooma Niazi, Gilda Diaz‐Fuentes · 2020

Malignant epithelioid tumors have been described in various organ systems, but are rarely seen in the brain. They are aggressive tumors and have high mortality. In certain cases, the immunohistochemistry (IHC) findings may not be sufficien…

A Rare Case of SplenicPneumocystis jiroveciiin a HIV-Positive Patient Open

Hafsa Abbas, Harish Patel, Ahmed Baiomi, Masooma Niazi, Trupti Vakde , et al. · 2020

Introduction . Human immunodeficiency virus (HIV) positive individuals with the CD4 count less than 200 cells/mm 3 are at risk for opportunistic infections. Pneumocystis jirovecii , a fungal pathogen, is a common cause of opportunistic inf…

"Garden in the Lungs": Deadly Diagnosis of Aspiration with Flexible Bronchoscopy Open

Maneesh Gaddam, O. Milian, Masooma Niazi, Ajsza Matela · 2020

A Rare Etiology of Abnormally Large Gastric Folds: Menetrier’s Disease Open

Muhammad Umar Kamal, Hassan Tariq, Vaniza Mehak, Sara Azam, Kishore Kumar , et al. · 2019

Menetrier’s disease (MD) is described as hypertrophied giant gastric folds causing hypoproteinemia due to protein losing gastropathy and is associated with higher risk of gastric adenocarcinoma. We present a case of a 58-year-old male who …

Lung mass with bilateral mediastinal hypermetabolic lymphadenopathy in a chronic smoker indicative of lung cancer? Open

Asghar Ali, Sindhaghatta Venkatram, Masooma Niazi, Gilda Diaz‐Fuentes · 2019

A Rare Case of Disseminated Mycobacterium avium-intracellulare Presenting as Proctitis Open

Chukwunonso Chime, Peter Bhandari, Masooma Niazi, Harish Patel · 2019

Mycobacterium avium intracellulare (MAI) infections are common in Human Immuno-deficiency Virus (HIV) positive patients. MAI infection can have localized or disseminated presentation, patients with low CD4 count presenting with disseminate…

Co-Occurrence of Rarest Type of Dysphagia Lusoria (Type N-1) and Eosinophilic Esophagitis in a Cognitively Disabled Individual Open

Kishore Kumar, Jasbir Makker, Hassan Tariq, Ariyo Ihimoyan, Chukwunonso Chime , et al. · 2019

Dysphagia is an expressive symptom, described by an individual as “difficulty in swallowing.” Dysphagia due to esophageal compression from an aberrant right subclavian artery is rare, and it is termed as “dysphagia lusoria.” We present a r…

Cytophagic Histiocytic Panniculitis (CHP) in a Patient with SLE Found after Autopsy: When a Rash Is “Complicated!” Open

Hafsa Abbas, Ahsan Aslam, Muhammad Saad, Masooma Niazi, Sridhar Chilimuri · 2019

Introduction . Cytophagic histolytic panniculitis (CHP) is a clinical disorder characterized by nodular panniculitis of the subcutaneous adipose tissue. It was first described in 1980 by Winkelmann. Histologically it is described as an inf…

Lung Cancer Presenting as Skin Metastasis of the Back and Hand: A Case Series and Literature Review Open

Misbahuddin Khaja, Daniel Mundt, Rizwan Ahmed Dudekula, Umair Ashraf, Shehriyar Mehershahi , et al. · 2019

Lung cancer has the highest mortality of all cancers in the United States. The incidence of lung cancer with metastases to the skin varies between 1–12%, with the highest incidence seen in men. Here, we present two cases of lung cancer pre…

Small-Cell Type, Poorly Differentiated Neuroendocrine Carcinoma of the Gallbladder: A Case Report and Review of the Literature Open

Kishore Kumar, Hassan Tariq, Rafeeq Ahmed, Chukwunonso Chime, Masooma Niazi , et al. · 2019

The poorly differentiated small-cell type, neuroendocrine carcinoma (NEC) of the gallbladder is a very uncommon subtype of a neuroendocrine tumor of the gastrointestinal tract. Nonsecretory NEC by virtue of its nonspecific and subtle clini…

Atypical Radiographic Presentation of Cryptococcus Pneumonia in a Newly Diagnosed HIV Patient Open

Arthur Cacacho, Umair Ashraf, Arsalan Rehmani, Masooma Niazi, Misbahuddin Khaja · 2019

Background . Cryptococcus infection is an opportunistic infection that occurs primarily among immunocompromised patients, and the morbidity and mortality of this infection is high if left unrecognized and untreated. There are no clinical o…

A Rare Case of DRESS (Drug Reaction with Eosinophilia and Systemic Symptoms) Syndrome with Cholecystitis in a Patient on Levetiracetam Open

Tushi Singh, Masooma Niazi, Kishore Karri, Donald Rudikoff, Efraín González · 2019

Case of Gastric Diffuse Large B-Cell Lymphoma Open

Usman Pirzada, Kishore Kumar, Hassan Tariq, Masooma Niazi, Jasbir Makker · 2019

The gastrointestinal (GI) tract is the predominant site of extra nodal lymphoma involvement. In the United States (US), gastric lymphoma is the most common extra nodal site of lymphoma. Most of these lesions are either extra nodal marginal…

Malignant Peritoneal Mesothelioma Without Asbestos Exposure Open

Hafsa Abbas, Julio C. Rodríguez, Hassan Tariq, Masooma Niazi, Ahmed Alemam , et al. · 2019

Malignant mesothelioma is a rare neoplasm of the serosal linings. Mesothelioma has been linked to asbestos exposure, with prior asbestos exposure linked to 33-50% of malignant peritoneal mesotheliomas. We describe a case of malignant perit…

Co-Occurrence of Myeloid Sarcoma of the Lymph Node and Acute Monocytic Myeloid Leukemia: A Case Report and Literature Review Open

Misbahuddin Khaja, Toolsie Omesh, Masooma Niazi, Danial Shaikh, Sitarama Arvind Mudunuru , et al. · 2018

Background: Acute myeloid leukemia (AML) is the most common leukemia in adults. According to the French-American-British (FAB) system, monocytic leukemia is classified as M5. Myeloid sarcoma further occurs in 3–5% of AML. Thi…

Poorly Differentiated Small-Cell-Type Neuroendocrine Carcinoma of the Prostate: A Case Report and Literature Review Open

Kishore Kumar, Rafeeq Ahmed, Chukwunonso Chime, Hassan Tariq, Masooma Niazi , et al. · 2018

Neuroendocrine cells are widespread throughout the body and can give rise of neuroendocrine tumors due to abnormal growth of the chromaffin cells. Neuroendocrine tumors divide into many subtypes based on tumor grade (Ki-67 index and mitoti…

Recurrent Mantle Cell Lymphoma Presenting as Gastrointestinal Bleeding Open

Rafeeq Ahmed, Kishore Kumar, Jasbir Makker, Masooma Niazi, Bhavna Balar · 2018

Mantle cell lymphoma is a rare and aggressive subtype of B-cell non-Hodgkin lymphomas. Mantle cell lymphoma frequently involves extranodal sites, and gastrointestinal tract is involved microscopically and macroscopically in more than 80% o…

Refractory Septic Shock due to Underlying Immunocompromised Disease: A Case of Fatal Peripheral T-Cell Lymphoma Not Otherwise Specified in a Young Hispanic Woman Open

Kishore Kumar, Muhammad Saad, Chukwunonso Chime, Kanthi Rekha Badipatla, Hassan Tariq , et al. · 2018

Peripheral T-cell lymphoma not otherwise specified (PTCL-NOS) is known as an unclassified group of non-Hodgkin lymphomas. PTCL-NOS is a subtype of peripheral T-cell lymphoma that accounts for 3% of all lymphomas in the United States. PTCL-…

A Rare Case of Colonic Metastases From Tonsillar Carcinoma: Case Report and Review of Literature Open

Hassan Tariq, Muhammad Umar Kamal, Shehriyar Mehershahi, Muhammad Saad, Sara Azam , et al. · 2018

The incidence of tonsillar cancer has increased by four times in the United States over the last few decades likely due to recent increase in human papilloma virus (HPV) infections. The stage of the tumor predicts likelihood of metastasis,…

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