Massimo Delledonne
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View article: The italian national genomic strategy: current status, challenges, and future perspectives in clinical practice and public health
The italian national genomic strategy: current status, challenges, and future perspectives in clinical practice and public health Open
This article presents the outcomes of a national initiative aimed at developing a technical document to support the future Italian National Genomic Strategy, carried out from 2021 to 2024 through the collaboration of 14 research institutio…
View article: Exploring Bat–Virus Interactions: Insights from a Study in the Gobi Desert
Exploring Bat–Virus Interactions: Insights from a Study in the Gobi Desert Open
In May 2022, an expedition was conducted in the Gobi Desert, Mongolia, to investigate the viral diversity of bats, recognized as reservoirs of emerging zoonotic viruses. Bats were captured in six oases using mist nets and were identified m…
View article: The lncRNA LOC100257036 and vvimiR156 modulate gibberellin signaling through AGAMOUS during cluster formation in Sistan Yaghooti grape
The lncRNA LOC100257036 and vvimiR156 modulate gibberellin signaling through AGAMOUS during cluster formation in Sistan Yaghooti grape Open
View article: The unexplored diversity of rough-seeded lupins provides rich genomic resources and insights into lupin evolution
The unexplored diversity of rough-seeded lupins provides rich genomic resources and insights into lupin evolution Open
View article: A journey of discovery: a multi-stage diagnostic procedure identifies Curtobacterium flaccumfaciens pv. allii as a new potential threat to maize
A journey of discovery: a multi-stage diagnostic procedure identifies Curtobacterium flaccumfaciens pv. allii as a new potential threat to maize Open
View article: The evolutionary history of the common bean (Phaseolus vulgaris) revealed by chloroplast and nuclear genomes analysis
The evolutionary history of the common bean (Phaseolus vulgaris) revealed by chloroplast and nuclear genomes analysis Open
Key message The origin of common bean was investigated throughout chloroplast and nuclear WGS data considering recombination events. Our results support the Mesoamerican origin of common bean. Abstract The remarkable evolutionary history o…
View article: Transcriptomic analysis reveals role of lncRNA LOC100257036 to regulate AGAMOUS during cluster compactness of Vitis vinifera cv. sistan yaghooti
Transcriptomic analysis reveals role of lncRNA LOC100257036 to regulate AGAMOUS during cluster compactness of Vitis vinifera cv. sistan yaghooti Open
Yaghooti grape, as the earliest grape variety in Iran, is considered as more resistant to heat, drought, and salinity than other cultivars. Cluster compactness is regarded as an inappropriate feature for the productivity of Yaghooti grape …
View article: Author Correction: Adaptive gene loss in the common bean pan-genome during range expansion and domestication
Author Correction: Adaptive gene loss in the common bean pan-genome during range expansion and domestication Open
View article: Adaptive gene loss in the common bean pan-genome during range expansion and domestication
Adaptive gene loss in the common bean pan-genome during range expansion and domestication Open
View article: Understanding the expression of gene families involved in anthocyanin biosynthesis during berry ripening: Tannat as a case study
Understanding the expression of gene families involved in anthocyanin biosynthesis during berry ripening: Tannat as a case study Open
The quality of wine is assessed, among other things, by its color, which is mainly due to its anthocyanin content. These pigments are polyphenols that give red, purple and blue hues depending on the relative proportion of anthocyanins prod…
View article: Landscape genomics highlights the adaptive evolution of chickpea
Landscape genomics highlights the adaptive evolution of chickpea Open
The structure of crop genetic diversity reflects spatial and ecological variations caused by population dynamics during adaptation to different agricultural environments. Landscape genomics can reveal patterns of neutral and adaptive varia…
View article: Haematococcus lacustris genome assembly and annotation reveal diploid genetic traits and stress-induced gene expression patterns
Haematococcus lacustris genome assembly and annotation reveal diploid genetic traits and stress-induced gene expression patterns Open
The green alga Haematococcus lacustris (formerly Haematococcus pluvialis) is a primary source of astaxanthin, a ketocarotenoid with high antioxidant activity and several industrial applications. Here, the Haematococcus lac…
View article: Molecular and Serological Detection of Bovine Coronaviruses in Marmots (Marmota marmota) in the Alpine Region
Molecular and Serological Detection of Bovine Coronaviruses in Marmots (Marmota marmota) in the Alpine Region Open
In this study, virological surveillance focused on coronaviruses in marmots in the Alpine region in 2022, captured as part of a population control reduction program in the Livigno area. Seventy-six faecal samples were randomly collected fr…
View article: A new, unusually large, Clavicornaltica Scherer, 1974 flea beetle from Borneo, described and sequenced in the field by citizen scientists (Coleoptera, Chrysomelidae, Galerucinae)
A new, unusually large, Clavicornaltica Scherer, 1974 flea beetle from Borneo, described and sequenced in the field by citizen scientists (Coleoptera, Chrysomelidae, Galerucinae) Open
The genus Clavicornaltica Scherer 1974 consists of very small, soil-dwelling flea beetles in South, Southeast and East Asia. Due to their diminutive size and morphological similarities, very little is known about their ecology and taxonomi…
View article: The unexplored diversity of wild lupins provides rich genomic resources and insights into lupin evolution
The unexplored diversity of wild lupins provides rich genomic resources and insights into lupin evolution Open
Lupin crops provide nutritious seeds as an excellent source of dietary protein. However, extensive genomic resources are needed for the adaptation of lupin crops, particularly to improve their nutritional value and facilitate their adaptat…
View article: Changes in the Adaptive Cellular Repertoire after Infection with Different SARS-CoV-2 VOCs in a Cohort of Vaccinated Healthcare Workers
Changes in the Adaptive Cellular Repertoire after Infection with Different SARS-CoV-2 VOCs in a Cohort of Vaccinated Healthcare Workers Open
Background: Currently approved vaccines are highly effective in protecting against hospitalization and severe COVID-19 infections. How pre-existing immunity responds to new variants with mutated antigens is crucial information for elucidat…
View article: Genotype Combinations Drive Variability in the Microbiome Configuration of the Rhizosphere of Maize/Bean Intercropping System
Genotype Combinations Drive Variability in the Microbiome Configuration of the Rhizosphere of Maize/Bean Intercropping System Open
In an intercropping system, the interplay between cereals and legumes, which is strongly driven by the complementarity of below-ground structures and their interactions with the soil microbiome, raises a fundamental query: Can different ge…
View article: Correlation between microbial communities and volatile organic compounds in an urban soil provides clues on soil quality towards sustainability of city flowerbeds
Correlation between microbial communities and volatile organic compounds in an urban soil provides clues on soil quality towards sustainability of city flowerbeds Open
Soil functionality is critical to the biosphere as it provides ecosystem services relevant for a healthy planet. The soil microbial composition is significantly impacted by anthropogenic activities, including urbanization. In this context,…
View article: Adaptive gene loss in the common bean pan-genome during range expansion and domestication
Adaptive gene loss in the common bean pan-genome during range expansion and domestication Open
The common bean ( Phaseolus vulgaris L.) is a crucial grain legume crop [1,2] whose life history offers an ideal evolutionary model to identify and study adaptive variants in wild and domestication populations [3]. Here we present the firs…
View article: Genotype combinations drive variability in the microbiome configuration of the rhizosphere of Maize/Bean intercropping system
Genotype combinations drive variability in the microbiome configuration of the rhizosphere of Maize/Bean intercropping system Open
In intercropping system, the interplay between cereals and legumes, which is strongly driven by complementarity of below-ground structures and their interactions with the soil microbiome, raises a fundamental query: Can different genotypes…
View article: Author Correction: Enhancer hijacking at the ARHGAP36 locus is associated with connective tissue to bone transformation
Author Correction: Enhancer hijacking at the ARHGAP36 locus is associated with connective tissue to bone transformation Open
View article: Comparative analysis of bioinformatics tools to characterize SARS-CoV-2 subgenomic RNAs
Comparative analysis of bioinformatics tools to characterize SARS-CoV-2 subgenomic RNAs Open
During the replication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), positive-sense genomic RNA and subgenomic RNAs (sgRNAs) are synthesized by a discontinuous process of transcription characterized by a template switch,…
View article: The evolutionary history of the common bean (<i>Phaseolus vulgaris</i>) revealed by chloroplast and nuclear genomes
The evolutionary history of the common bean (<i>Phaseolus vulgaris</i>) revealed by chloroplast and nuclear genomes Open
The remarkable evolutionary history of the common bean ( Phaseolus vulgaris L. ) has led to the emergence of three wild main genepools corresponding to three different ecogeographic areas: Mesoamerica, the Andes and northern Peru/Ecuador. …
View article: An isoform of the giant protein titin is a master regulator of human T lymphocyte trafficking
An isoform of the giant protein titin is a master regulator of human T lymphocyte trafficking Open
Response to multiple microenvironmental cues and resilience to mechanical stress are essential features of trafficking leukocytes. Here, we describe unexpected role of titin (TTN), the largest protein encoded by the human genome, in the re…
View article: CRISPR-Cas9-based repeat depletion for high-throughput genotyping of complex plant genomes
CRISPR-Cas9-based repeat depletion for high-throughput genotyping of complex plant genomes Open
High-throughput genotyping enables the large-scale analysis of genetic diversity in population genomics and genome-wide association studies that combine the genotypic and phenotypic characterization of large collections of accessions. Sequ…
View article: Enhancer hijacking at the ARHGAP36 locus is associated with connective tissue to bone transformation
Enhancer hijacking at the ARHGAP36 locus is associated with connective tissue to bone transformation Open
Heterotopic ossification is a disorder caused by abnormal mineralization of soft tissues in which signaling pathways such as BMP, TGFβ and WNT are known key players in driving ectopic bone formation. Identifying novel genes and pathways re…
View article: A new semi-slug of the genus Microparmarion from Brunei, discovered, described and DNA-barcoded on citizen-science 'taxon expeditions' (Gastropoda, Stylommatophora, Ariophantidae)
A new semi-slug of the genus Microparmarion from Brunei, discovered, described and DNA-barcoded on citizen-science 'taxon expeditions' (Gastropoda, Stylommatophora, Ariophantidae) Open
During citizen-science expeditions to the Ulu Temburong National Park, Brunei, several individuals were collected of a semi-slug species of the genus Microparmarion that, based on morphology and in-the-field DNA-barcoding, was found to be …
View article: Supplementary Figures 1-9 from Centrosome Linker–induced Tetraploid Segregation Errors Link Rhabdoid Phenotypes and Lethal Colorectal Cancers
Supplementary Figures 1-9 from Centrosome Linker–induced Tetraploid Segregation Errors Link Rhabdoid Phenotypes and Lethal Colorectal Cancers Open
S1. Whole exome sequencing analysis of two rhabdoid colorectal cancers (RC). S2. Non-silent somatic mutations in rhabdoid tumours are enriched in centrosome-microtubule components. S3. Effect of CROCC mutations on centrosome phenotype. S4.…
View article: Supplementary Tables 1-9 from Centrosome Linker–induced Tetraploid Segregation Errors Link Rhabdoid Phenotypes and Lethal Colorectal Cancers
Supplementary Tables 1-9 from Centrosome Linker–induced Tetraploid Segregation Errors Link Rhabdoid Phenotypes and Lethal Colorectal Cancers Open
Supplementary Table 1. Clinicopathological, immunohistochemical and molecular features of the 12 rhabdoid colorectal cancers7 Supplementary Table 2. Somatic mutations of candidate genes (15 out of 20 are reported) shared by the two rhabdoi…
View article: Supplementary Materials and Methods from Centrosome Linker–induced Tetraploid Segregation Errors Link Rhabdoid Phenotypes and Lethal Colorectal Cancers
Supplementary Materials and Methods from Centrosome Linker–induced Tetraploid Segregation Errors Link Rhabdoid Phenotypes and Lethal Colorectal Cancers Open
The file contains supplementary Materials and Methods