Matej Adámik
YOU?
Author Swipe
View article: Telomerase RNA in Hymenoptera (Insecta) switched to plant/ciliate-like biogenesis
Telomerase RNA in Hymenoptera (Insecta) switched to plant/ciliate-like biogenesis Open
In contrast to the catalytic subunit of telomerase, its RNA subunit (TR) is highly divergent in size, sequence and biogenesis pathways across eukaryotes. Current views on TR evolution assume a common origin of TRs transcribed with RNA poly…
View article: Hymenoptera (Insecta) telomerase RNAs switched to plant/ciliate-like biogenesis
Hymenoptera (Insecta) telomerase RNAs switched to plant/ciliate-like biogenesis Open
In contrast to the catalytic subunit of telomerase, its RNA subunit (TR) is highly divergent in size, sequence and biogenesis pathways across eukaryotes. Current views on TR evolution assume a common origin of TRs transcribed with RNA poly…
View article: p53 Binds Preferentially to Non-B DNA Structures Formed by the Pyrimidine-Rich Strands of GAA·TTC Trinucleotide Repeats Associated with Friedreich’s Ataxia
p53 Binds Preferentially to Non-B DNA Structures Formed by the Pyrimidine-Rich Strands of GAA·TTC Trinucleotide Repeats Associated with Friedreich’s Ataxia Open
Expansions of trinucleotide repeats (TNRs) are associated with genetic disorders such as Friedreich’s ataxia. The tumor suppressor p53 is a central regulator of cell fate in response to different types of insults. Sequence and structure-se…
View article: p53 Specifically Binds Triplex DNA In Vitro and in Cells
p53 Specifically Binds Triplex DNA In Vitro and in Cells Open
Triplex DNA is implicated in a wide range of biological activities, including regulation of gene expression and genomic instability leading to cancer. The tumor suppressor p53 is a central regulator of cell fate in response to different ty…
View article: Wild-type p53 binds to <i>MYC</i> promoter G-quadruplex
Wild-type p53 binds to <i>MYC</i> promoter G-quadruplex Open
G-quadruplexes are four-stranded nucleic acid structures that are implicated in the regulation of transcription, translation and replication. Genome regions enriched in putative G-quadruplex motifs include telomeres and gene promoters. Tum…
View article: p53 binds human telomeric G-quadruplex in vitro
p53 binds human telomeric G-quadruplex in vitro Open
View article: SCS-binding of p53 proteins by magnetic beads-based immunoprecipitation assay (MBIP) <i>in vitro and ex vivo</i>.
SCS-binding of p53 proteins by magnetic beads-based immunoprecipitation assay (MBIP) <i>in vitro and ex vivo</i>. Open
A) Scheme of the procedure (from left to right): the cell lysate or purified proteins were mixed with antibody (Ab) and then with a DNA substrate and incubated to allow formation of the Ab-p53-DNA complex (a). Then, the complex is captured…