Mateusz M. Pluciński
YOU?
Author Swipe
View article: Efficacy and safety of artemether-lumefantrine (AL) and artesunate-amodiaquine (ASAQ) for the treatment of uncomplicated Plasmodium falciparum malaria in Liberia, 2022–2023
Efficacy and safety of artemether-lumefantrine (AL) and artesunate-amodiaquine (ASAQ) for the treatment of uncomplicated Plasmodium falciparum malaria in Liberia, 2022–2023 Open
The PCR-corrected ACPR efficacy greater than the 90% WHO threshold, and day 3 slide positivity rate demonstrate that AL and ASAQ are both effective treatments for uncomplicated malaria in Liberia.
View article: Antimalarial drug resistance and population structure of Plasmodium falciparum in Mozambique using genomic surveillance at health facilities in 2021 and 2022
Antimalarial drug resistance and population structure of Plasmodium falciparum in Mozambique using genomic surveillance at health facilities in 2021 and 2022 Open
Monitoring the emergence and spread of drug-resistant parasites is essential for effective malaria control. Here, we describe the prevalence of genetic markers of Plasmodium falciparum antimalarial drug resistance and parasite population s…
View article: Assessment of different techniques and markers to distinguish recrudescence from new infection in an antimalarial therapeutic efficacy study conducted in Rwanda
Assessment of different techniques and markers to distinguish recrudescence from new infection in an antimalarial therapeutic efficacy study conducted in Rwanda Open
Introduction Accurate estimation of antimalarial drug efficacy against P. falciparum requires PCR correction to distinguish recrudescence from new infection in recurrent infections. Genotyping length polymorphic or SNP-rich markers, and va…
View article: Incidence of and Risk Factors for SARS-CoV-2 Infection Among Vaccinated Healthcare Workers During Emergence of SARS-CoV-2 Gamma Variant in the Amazon Region, Brazil, 2021
Incidence of and Risk Factors for SARS-CoV-2 Infection Among Vaccinated Healthcare Workers During Emergence of SARS-CoV-2 Gamma Variant in the Amazon Region, Brazil, 2021 Open
Background The emergence of new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants poses a significant threat to public health and healthcare workers (HCWs). The SARS-CoV-2 Gamma variant emerged in Manaus, Brazil, in Dec…
View article: Antibody Response in Healthcare Workers During the SARS-CoV-2 Gamma Variant Outbreak in Manaus, Brazil
Antibody Response in Healthcare Workers During the SARS-CoV-2 Gamma Variant Outbreak in Manaus, Brazil Open
Background This study aimed to evaluate severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)–specific binding and neutralizing antibody responses in healthcare workers (HCWs) who received coronavirus disease 2019 (COVID-19) vaccine…
View article: Efficacy of artemether-lumefantrine, artesunate-amodiaquine, dihydroartemisinin-piperaquine and artesunate-pyronaridine for the treatment of uncomplicated Plasmodium falciparum malaria in Mozambique, 2022
Efficacy of artemether-lumefantrine, artesunate-amodiaquine, dihydroartemisinin-piperaquine and artesunate-pyronaridine for the treatment of uncomplicated Plasmodium falciparum malaria in Mozambique, 2022 Open
Clinicaltrials.gov: NCT05343312.
View article: Plasmodium falciparum multidrug resistance 1 gene polymorphisms associated with outcomes after anti-malarial treatment
Plasmodium falciparum multidrug resistance 1 gene polymorphisms associated with outcomes after anti-malarial treatment Open
View article: Assessment of different genotyping markers and algorithms for distinguishing Plasmodium falciparum recrudescence from reinfection in Uganda
Assessment of different genotyping markers and algorithms for distinguishing Plasmodium falciparum recrudescence from reinfection in Uganda Open
View article: Principal component analysis of the Serological response to Plasmodium Falciparum using a Multiplex bead-based assay in Nigeria
Principal component analysis of the Serological response to Plasmodium Falciparum using a Multiplex bead-based assay in Nigeria Open
Characterization of serological responses to Plasmodium falciparum ( Pf ) is of interest to understand disease burden and transmission dynamics; however, their interpretation is challenging. Dried blood spots from 30,815 participants aged …
View article: Assessment of different genotyping markers and algorithms for distinguishing Plasmodium falciparum recrudescence from reinfection in Uganda
Assessment of different genotyping markers and algorithms for distinguishing Plasmodium falciparum recrudescence from reinfection in Uganda Open
Antimalarial therapeutic efficacy studies are vital for monitoring the efficacy of antimalarial drugs in malaria-endemic regions. The WHO recommends genotyping of polymorphic markers including msp-1, msp-2, and glurp to aid distinguishing …
View article: Analysis of Care-seeking Pathway and Factors Influencing Early and Appropriate Care-seeking for Malaria Patients in the Republic of Guinea, 2022-2023
Analysis of Care-seeking Pathway and Factors Influencing Early and Appropriate Care-seeking for Malaria Patients in the Republic of Guinea, 2022-2023 Open
Aim: This this study was conducted to analyze the diagnostic pathway and the factors associated with early and appropriate care-seeking for malaria patients in the Republic of Guinea. Methods: A cross-sectional study was carried out betwee…
View article: Review 2: "Evidence of Artemisinin Partial Resistance in North-Western Tanzania: Clinical and Drug Resistance Markers Study"
Review 2: "Evidence of Artemisinin Partial Resistance in North-Western Tanzania: Clinical and Drug Resistance Markers Study" Open
Overall, both the reviewers highlight that this study has important findings and significantly contributes to molecular surveillance efforts in Africa. However, they expressed concern about the study's analytical methodology and the overal…
View article: Reviews of "Evidence of Artemisinin Partial Resistance in North-Western Tanzania: Clinical and Drug Resistance Markers Study"
Reviews of "Evidence of Artemisinin Partial Resistance in North-Western Tanzania: Clinical and Drug Resistance Markers Study" Open
View article: Therapeutic response to four artemisinin-based combination therapies in Angola, 2021
Therapeutic response to four artemisinin-based combination therapies in Angola, 2021 Open
Monitoring antimalarial efficacy is important to detect the emergence of parasite drug resistance. Angola conducts in vivo therapeutic efficacy studies (TESs) every 2 years in its fixed sentinel sites in Benguela, Lunda Sul, and Zaire prov…
View article: High Efficacy of Artemether-Lumefantrine and Artesunate-Pyronaridine with Single Low Dose Primaquine in Adults with Plasmodium Falciparum with High Prevalence of Markers of Partial Artemisinin Resistance and Pfhrp2/3 Gene Deletions in Ethiopia: A Single-Blind Randomized Controlled Trial
High Efficacy of Artemether-Lumefantrine and Artesunate-Pyronaridine with Single Low Dose Primaquine in Adults with Plasmodium Falciparum with High Prevalence of Markers of Partial Artemisinin Resistance and Pfhrp2/3 Gene Deletions in Ethiopia: A Single-Blind Randomized Controlled Trial Open
View article: Out of Africa: Increasing reports of artemether-lumefantrine treatment failures of uncomplicated <i>Plasmodium falciparum</i> infection
Out of Africa: Increasing reports of artemether-lumefantrine treatment failures of uncomplicated <i>Plasmodium falciparum</i> infection Open
Studies of travellers returning from Africa with uncomplicated Plasmodium falciparum infection are starting to provide signals of failure of artemether-lumefantrine, a first-line treatment of uncomplicated malaria. Traveller-based reports …
View article: Targeted and whole-genome sequencing reveal a north-south divide in P. falciparum drug resistance markers and genetic structure in Mozambique
Targeted and whole-genome sequencing reveal a north-south divide in P. falciparum drug resistance markers and genetic structure in Mozambique Open
View article: Molecular Markers of Sulfadoxine-Pyrimethamine Resistance in Samples from Children with Uncomplicated Plasmodium falciparum at Three Sites in Angola in 2019
Molecular Markers of Sulfadoxine-Pyrimethamine Resistance in Samples from Children with Uncomplicated Plasmodium falciparum at Three Sites in Angola in 2019 Open
Sulfadoxine-pyrimethamine (SP) is used for prevention of malaria in pregnant women in Angola. We sequenced the Plasmodium falciparum dihydrofolate reductase ( pfdhfr ) and dihydropteroate synthase ( pfdhps ) genes, implicated in SP resista…
View article: Epidemiologic Utility of a Framework for Partition Number Selection When Dissecting Hierarchically Clustered Genetic Data Evaluated on the Intestinal Parasite <i>Cyclospora cayetanensis</i>
Epidemiologic Utility of a Framework for Partition Number Selection When Dissecting Hierarchically Clustered Genetic Data Evaluated on the Intestinal Parasite <i>Cyclospora cayetanensis</i> Open
Comparing parasite genotypes to inform parasitic disease outbreak investigations involves computation of genetic distances that are typically analyzed by hierarchical clustering to identify related isolates, indicating a common source. A l…
View article: An improved framework for detecting discrete epidemiologically meaningful partitions in hierarchically clustered genetic data
An improved framework for detecting discrete epidemiologically meaningful partitions in hierarchically clustered genetic data Open
Motivation Hierarchical clustering of microbial genotypes has the limitation that hierarchical clusters are nested, where smaller groups of related isolates exist within larger groups that get progressively larger as relationships become i…
View article: Performance of antigen detection for HRP2-based malaria rapid diagnostic tests in community surveys: Tanzania, July–November 2017
Performance of antigen detection for HRP2-based malaria rapid diagnostic tests in community surveys: Tanzania, July–November 2017 Open
View article: STUDY ON THE PREVALENCE OF PLASMODIUM SPECIES IN THREE PROVINCES OF ANGOLA, AND DETERMINATION OF THE PERCENTAGE OF MIXED INFECTIONS, 2019
STUDY ON THE PREVALENCE OF PLASMODIUM SPECIES IN THREE PROVINCES OF ANGOLA, AND DETERMINATION OF THE PERCENTAGE OF MIXED INFECTIONS, 2019 Open
In Angola, four types of Plasmodium are diagnosed: P.falciparum, P.Vivax, P.Malariae and P.ovale.P.falciparum is predominant in 87% according to previous studies.Still on the basis of some studies, there is a high percentage of mixed infec…
View article: Novel application of one-step pooled molecular testing and maximum likelihood approaches to estimate the prevalence of malaria parasitaemia among rapid diagnostic test negative samples in western Kenya
Novel application of one-step pooled molecular testing and maximum likelihood approaches to estimate the prevalence of malaria parasitaemia among rapid diagnostic test negative samples in western Kenya Open
View article: Predicting Plasmodium falciparum infection status in blood using a multiplexed bead-based antigen detection assay and machine learning approaches
Predicting Plasmodium falciparum infection status in blood using a multiplexed bead-based antigen detection assay and machine learning approaches Open
Background Plasmodium blood-stage infections can be identified by assaying for protein products expressed by the parasites. While the binary result of an antigen test is sufficient for a clinical result, greater nuance can be gathered for …
View article: Evaluation of various distance computation methods for construction of haplotype-based phylogenies from large MLST datasets
Evaluation of various distance computation methods for construction of haplotype-based phylogenies from large MLST datasets Open
View article: Adaptation to a Multiplex Bead Assay and Seroprevalence to Rift Valley Fever N Protein: Nampula Province, Mozambique, 2013-2014
Adaptation to a Multiplex Bead Assay and Seroprevalence to Rift Valley Fever N Protein: Nampula Province, Mozambique, 2013-2014 Open
Due to sporadic transmission, human contact with Rift Valley Fever Virus (RVFV) is difficult to ascertain at a population level. Detection of antibodies against RVFV antigens assist in estimating exposure as antibodies remain in the host l…
View article: Antibody dynamics in children with first or repeat Plasmodium falciparum infections
Antibody dynamics in children with first or repeat Plasmodium falciparum infections Open
Immunoglobulin (Ig) production during and after infection with Plasmodium parasites is one of the greatest adaptive immune defenses the human host has against this parasite. Infection with P. falciparum has been shown to induce different B…
View article: STARTER Checklist for Antimalarial Therapeutic Efficacy Reporting
STARTER Checklist for Antimalarial Therapeutic Efficacy Reporting Open
Efficacious antimalarials are a cornerstone of the global effort to control and eliminate malaria.However, the spread of drug resistance threatens gains achieved over the early years of this century.Of particular concern is widespread arte…
View article: STARTER checklist for antimalarial therapeutic efficacy reporting
STARTER checklist for antimalarial therapeutic efficacy reporting Open
View article: Risk Factors for Ebola Virus Persistence in Semen of Survivors in Liberia
Risk Factors for Ebola Virus Persistence in Semen of Survivors in Liberia Open
Background Long-term persistence of Ebola virus (EBOV) in immunologically privileged sites has been implicated in recent outbreaks of Ebola virus disease (EVD) in Guinea and the Democratic Republic of Congo. This study was designed to unde…