Mateusz Markowicz
YOU?
Author Swipe
View article: Human epidermal Langerhans cells induce tolerance and hamper T cell function upon tick-borne pathogen transmission
Human epidermal Langerhans cells induce tolerance and hamper T cell function upon tick-borne pathogen transmission Open
Arthropods are ancient vectors of infectious disease that alter the immune environment of the skin during feeding. The epidermis and its immune sentinels, including Langerhans cells, are critical for protection against ectoparasitic arthro…
View article: The real-time PCR targeting the phage terminase (terL) is not suitable for diagnostics of human Borrelia infections in Europe
The real-time PCR targeting the phage terminase (terL) is not suitable for diagnostics of human Borrelia infections in Europe Open
Bacteria of the Borrelia burgdorferi sensu lato (sl) species complex can cause Lyme borreliosis (LB) in humans. PCR plays an important role in the diagnosis of many infectious diseases but it is used auxiliary in LB diagnostics. Here, we r…
View article: The choice of study designs of diagnostic accuracy using Borrelia specific IgG and IgM antibodies for the diagnosis of Lyme borreliosis
The choice of study designs of diagnostic accuracy using Borrelia specific IgG and IgM antibodies for the diagnosis of Lyme borreliosis Open
Case-control (two-gate design) studies, case series, and seroprevalence studies representing the range of LB in different populations are necessary to assess the diagnostic accuracy of serological tests for LB. A broader range of studies s…
View article: Modeling spatio-temporal annual changes in the probability of human tick-borne encephalitis (TBE) occurrence across Europe
Modeling spatio-temporal annual changes in the probability of human tick-borne encephalitis (TBE) occurrence across Europe Open
Introduction Tick-borne encephalitis (TBE), caused by tick-borne encephalitis virus (TBEV), is a zoonotic disease that can cause severe neurological symptoms. Given the increasing number of reported human TBE cases in Europe, a spatio-temp…
View article: Hyalomma marginatum - A silent stowaway after vacation at the Adriatic Sea
Hyalomma marginatum - A silent stowaway after vacation at the Adriatic Sea Open
Hyalomma marginatum is an invasive tick species capable of transmitting pathogens that cause severe diseases such as Crimean-Congo hemorrhagic fever. In Austria, H. marginatum occurs sporadically, and migratory birds are believed to bring …
View article: Comparison of a multiplex PCR with DNA barcoding for identification of container breeding mosquito species
Comparison of a multiplex PCR with DNA barcoding for identification of container breeding mosquito species Open
Background Identification of mosquitoes greatly relies on morphological specification. Since some species cannot be distinguished reliably by morphological methods, it is important to incorporate molecular techniques into the diagnostic pi…
View article: Recurrent, ICD-associated L. monocytogenes bacteremia with septic pulmonary embolisms over a 3-year period
Recurrent, ICD-associated L. monocytogenes bacteremia with septic pulmonary embolisms over a 3-year period Open
Successful treatment of patients with recurring listeria episodes due to colonized foreign material is often challenging, typically requiring a combination of antimicrobial treatment and surgical removal. Here, we present a particularly ch…
View article: Three Cases of Tickborne <i>Francisella tularensis</i> Infection, Austria, 2022
Three Cases of Tickborne <i>Francisella tularensis</i> Infection, Austria, 2022 Open
Tularemia is increasing in Austria. We report Francisella tularensis subspecies holarctica isolated from 3 patients who had been bitten by arthropods. Next-generation sequencing showed substantial isolate similarity. Clinicians should cons…
View article: Spatiotemporal spread of tick-borne encephalitis in the EU/EEA, 2012 to 2020
Spatiotemporal spread of tick-borne encephalitis in the EU/EEA, 2012 to 2020 Open
Background Tick-borne encephalitis (TBE) is a vaccine-preventable disease involving the central nervous system. TBE became a notifiable disease on the EU/EEA level in 2012. Aim We aimed to provide an updated epidemiological assessment of T…
View article: Tick feeding modulates the human skin immune landscape to facilitate tick-borne pathogen transmission
Tick feeding modulates the human skin immune landscape to facilitate tick-borne pathogen transmission Open
During cutaneous tick attachment, the feeding cavity becomes a site of transmission for tick salivary compounds and tick-borne pathogens. However, the immunological consequences of tick feeding for human skin remain unclear. Here, we asses…
View article: Borrelia Ecology and Evolution: Ticks and Hosts and the Environment
Borrelia Ecology and Evolution: Ticks and Hosts and the Environment Open
The genus Borrelia encompasses bacterial pathogens that can cause Lyme borreliosis (LB) and relapsing fever (RF) [...]
View article: Persistent Lyme disease with cutaneous <i>Borrelia</i> biofilm formation
Persistent Lyme disease with cutaneous <i>Borrelia</i> biofilm formation Open
[Image: see text]
View article: Isolation of Francisella tularensis from Skin Ulcer after a Tick Bite, Austria, 2020
Isolation of Francisella tularensis from Skin Ulcer after a Tick Bite, Austria, 2020 Open
Ulceroglandular tularemia is caused by the transmission of Francisella tularensis by arthropods to a human host. We report a case of tick-borne tularemia in Austria which was followed by an abscess formation in a lymph node, making drainag…
View article: Infections with Tickborne Pathogens after Tick Bite, Austria, 2015–2018
Infections with Tickborne Pathogens after Tick Bite, Austria, 2015–2018 Open
The aim of this prospective study was to assess the risk for tickborne infections after a tick bite. A total of 489 persons bitten by 1,295 ticks were assessed for occurrence of infections with Borrelia burgdorferi sensu lato, Anaplasma ph…
View article: Glycerophosphodiester Phosphodiesterase Identified as Non-Reliable Serological Marker for Borrelia miyamotoi Disease
Glycerophosphodiester Phosphodiesterase Identified as Non-Reliable Serological Marker for Borrelia miyamotoi Disease Open
The relapsing fever group Borrelia miyamotoi is an emerging tick-borne pathogen. Diagnosis of infection is currently mainly based on serological methods detecting antibodies against B. miyamotoi glycerophosphodiester phosphodiesterase (Glp…
View article: Identification and Characterization of “Candidatus Rickettsia Thierseensis”, a Novel Spotted Fever Group Rickettsia Species Detected in Austria
Identification and Characterization of “Candidatus Rickettsia Thierseensis”, a Novel Spotted Fever Group Rickettsia Species Detected in Austria Open
Rickettsia spp. are the second most common pathogens detected in Ixodes ricinus ticks in Austria after Borrelia burgdorferi sensu lato. Species belonging to the spotted fever group (SFG) are the causative agents for tick-borne rickettsiosi…
View article: Human <i>Borrelia miyamotoi</i> Infection, Austria
Human <i>Borrelia miyamotoi</i> Infection, Austria Open
We report a human case of Borrelia miyamotoi infection diagnosed in Austria. Spirochetes were detected in Giemsa-stained blood smears. The presence of B. miyamotoi in the patient's blood was confirmed by PCR, and phylogenetic analysis iden…
View article: Lyme Borreliosis with Scalp Eschar Mimicking Rickettsial Infection, Austria
Lyme Borreliosis with Scalp Eschar Mimicking Rickettsial Infection, Austria Open
We report on a patient in Austria with scalp eschar and neck lymphadenopathy. Rickettsial etiology was excluded by culture, PCR, and serologic tests. Borrelia afzelii was identified from the eschar swab by PCR. Lyme borreliosis can mimic r…
View article: Molecular diagnosis of autochthonous human anaplasmosis in Austria – an infectious diseases case report
Molecular diagnosis of autochthonous human anaplasmosis in Austria – an infectious diseases case report Open
Background The diagnosis of human anaplasmosis remains elusive and is probably often missed. This case report highlights the efficacy of molecular diagnostic techniques. Case presentation We would like to report the case of a 74-year-old m…
View article: Severe Myasthenic Manifestation of Leptospirosis Associated with New Sequence Type of<i>Leptospira interrogans</i>
Severe Myasthenic Manifestation of Leptospirosis Associated with New Sequence Type of<i>Leptospira interrogans</i> Open
We report the rapid development of a myasthenic crisis as the first-time manifestation of myasthenia gravis. The symptoms developed in the course of acute leptospirosis associated with a new sequence type of Leptospira interrogans. Antibio…
View article: Outbreak of infestation with body lice in a home for assisted living, Austria, 2018
Outbreak of infestation with body lice in a home for assisted living, Austria, 2018 Open
Purpose: On 29 May 2018, the Austrian Agency of Health (AGES) was contacted by the head of a home for assisted living, which had 11 residents. She reported significant pest infestation, occurrence of vermin for three days throughout the wh…
View article: Adult Hyalomma marginatum tick positive for Rickettsia aeschlimannii in Austria, October 2018
Adult Hyalomma marginatum tick positive for Rickettsia aeschlimannii in Austria, October 2018 Open
We report on a non-indigenous adult Hyalomma marginatum tick in Austria carrying the human pathogenic Rickettsia aeschlimannii ; presumably introduced as a nymph via migratory birds and completed the moulting within the same year. It was n…
View article: Bacillary angiomatosis presenting with facial tumor and multiple abscesses
Bacillary angiomatosis presenting with facial tumor and multiple abscesses Open
Our case shows that rare opportunistic, vector-borne infections, usually associated with poverty, can lead to diagnosis of HIV even in well-developed countries. Furthermore, we provide details on clinical manifestation and diagnostic work-…