Mathias Chéa
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View article: Impact of direct oral anticoagulant treatment on management and outcomes of patients with hip fractures by monitoring assays. A population-based study of a cohort from the Geriatric Perioperative Unit
Impact of direct oral anticoagulant treatment on management and outcomes of patients with hip fractures by monitoring assays. A population-based study of a cohort from the Geriatric Perioperative Unit Open
NCT06382584 (registration date: 2024-04-24, registered retrospectively.
View article: Psychological Stress and Venous Thromboembolism: A Narrative Overview
Psychological Stress and Venous Thromboembolism: A Narrative Overview Open
“There is a tendency among young men about hospitals to study the cases, not the patients and, in the interest they take in the disease, lose sight of the individual [...]
View article: Minimal Residual Disease in Acute Myeloid Leukemia: Old and New Concepts
Minimal Residual Disease in Acute Myeloid Leukemia: Old and New Concepts Open
Minimal residual disease (MRD) is of major importance in onco-hematology, particularly in acute myeloid leukemia (AML). MRD measures the amount of leukemia cells remaining in a patient after treatment, and is an essential tool for disease …
View article: To be hematopoietic, or not to be: That is the neoplastic cell's question
To be hematopoietic, or not to be: That is the neoplastic cell's question Open
A 60-year-old woman was referred for investigation of unexplained chronic anemia. Her medical history included adenocarcinoma of the breast, without lymph node involvement, diagnosed 7 years previously and treated by mastectomy without rad…
View article: Vital NETosis vs. suicidal NETosis during normal pregnancy and preeclampsia
Vital NETosis vs. suicidal NETosis during normal pregnancy and preeclampsia Open
Background: NETosis occurs in the context of infection or inflammation and results in the expulsion of decondensed DNA filaments called NETs (Neutrophil Extracellular Traps) into the extracellular environment. NETosis activates coagulation…
View article: Direct blood fluorescence signal intensity of neutrophils (NEU-SFL): A predictive marker of death in hospitalized COVID-19 patients?
Direct blood fluorescence signal intensity of neutrophils (NEU-SFL): A predictive marker of death in hospitalized COVID-19 patients? Open
Introduction Coronavirus disease 2019 (COVID-19) is a respiratory disease triggered by immunopathological mechanisms that cause excessive inflammation and leukocyte dysfunction. Neutrophils play a critical role in the innate immunity and a…
View article: Systemic and medullary blastic plasmacytoid dendritic cell invasion
Systemic and medullary blastic plasmacytoid dendritic cell invasion Open
A 67-year-old man with history of idiopathic thrombocytopenia since 2010 was referred by his primary care physician for leukocytosis (98,000/mm3) with thrombocytopenia (<5000 mm3) and anemia (Haemoglobin at 7,6 g/dl) to the emergency depar…
View article: Atypical cytologic mantle cell lymphoma presentation
Atypical cytologic mantle cell lymphoma presentation Open
A 61-year-old patient presents with monoclonal B lymphocytosis diagnosed in 2014 with initial moderate splenic involvement without any clinical symptoms. In 2021, during a follow-up workup, a Positron Emission Tomography scan is performed …
View article: The Risk of Thrombosis Around Pregnancy: Where Do We Stand?
The Risk of Thrombosis Around Pregnancy: Where Do We Stand? Open
Pregnancy and puerperium increase the relative risk of venous thromboembolism (VTE) and the absolute risk remains low, around 1 per 1,000, with induced mortality of around 1 per 100,000. Analysis of large databases has helped specify the m…
View article: Antiphospholipid syndrome in pregnancy: Neuro-psychiatric aspects
Antiphospholipid syndrome in pregnancy: Neuro-psychiatric aspects Open
Nonvascular neurological manifestations of antiphospholipid antibodies (aPLAbs) are emerging and, among these, several neuropsychiatric shymptoms. Psychiatric diseases are gradually being considered as organic illnesses of the brain. The r…