Mathieu Luyckx
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Adjuvant treatment algorithm based on recent ESGO/ESTRO/ESP guidelines for early endometrial carcinoma according to prognostic risk groups Open
The incidence of endometrial cancer (EC) is unfortunately increasing. Often diagnosis is made at an early stage and surgery is the curative treatment. Nevertheless, adjuvant treatment is proposed to reduce the risk of relapse. This treatme…
The learning curve of V-NOTES hysterectomy: a single-surgeon experience Open
Purpose Vaginal natural orifice transluminal endoscopic surgery (V-NOTES) has emerged as an innovative surgical approach that combines the advantages of endoscopic surgery with those of the vaginal approach. This article presents the initi…
Atypical presentation of herpes simplex virus 2 primary infection: a case report Open
Herpes simplex virus infection should be considered as a possible cause of cervicitis, even in the absence of typical genital lesions. Early detection of herpes simplex virus allows early treatment, helping to reduce the duration and sever…
Intraoperative Ketorolac and Outcomes after Ovarian Cancer Surgery Open
Introduction: Surgery is the cornerstone of ovarian cancer treatment. However, surgery and perioperative inflammation have been described as potentially pro-metastagenic. In various animal models and other human cancers, intraoperative adm…
HELIOS-expressing human CD8 T cells exhibit limited effector functions Open
Introduction The transcription factor HELIOS is primarily known for its expression in CD4 regulatory T cells, both in humans and mice. In mice, HELIOS is found in exhausted CD8 T cells. However, information on human HELIOS + CD8 T cells is…
Immunosuppressive low-density neutrophils in the blood of cancer patients display a mature phenotype Open
The presence of human neutrophils in the tumor microenvironment is strongly correlated to poor overall survival. Most previous studies have focused on the immunosuppressive capacities of low-density neutrophils (LDN), also referred to as g…
View article: #630 Lower-limb lymphedema after sentinel lymph node biopsy in cervical cancer patients: final results of the SENTIX prospective international study (CEEGOG CX-01/ENGOT-Cx2)
#630 Lower-limb lymphedema after sentinel lymph node biopsy in cervical cancer patients: final results of the SENTIX prospective international study (CEEGOG CX-01/ENGOT-Cx2) Open
Introduction/Background Background The sentinel lymph node (SLN) concept was developed with the purpose of alleviating postoperative morbidity, particularly lower limb lymphedema (LLL). We report the final analysis of the occurrence of LLL…
Hysteroscopic management of molar pregnancy: A series of 36 cases Open
Background: Hydatidiform Mole (HM) is the most common form of gestational trophoblastic disease. Dilatation and curettage is the classical treatment of this affection. Hysteroscopic resection (HsR) is an alternative for the treatment of in…
Recurrent High Grade Serous Ovarian Cancer Management Open
Despite an aggressive treatment strategy for high grade serous ovarian cancer (HGSOC) that incorporates cytoreduction, platinum compounds, anti-angiogenic agents, and poly (ADP-ribose) polymerase (PARP) inhibitors, most patients, especiall…
P-339 Fertility outcomes after laparoscopic bladder endometriosis excision using a CO2 laser: 20-year retrospective analysis in an expert center Open
Study question To evaluate fertility outcomes after laparoscopic bladder endometriosis (BE) excision in patients presenting with a post operative pregnancy wish or pre-operative infertility. Summary answer Surgical excision of BE is follow…
View article: 1078 Implementation of the Sentinel node technique for endometrial cancer in Belgium: a multicentric retrospective study from 2015 to 2020
1078 Implementation of the Sentinel node technique for endometrial cancer in Belgium: a multicentric retrospective study from 2015 to 2020 Open
Introduction/Background* Sentinel node is a very powerful tool in endometrial cancer, giving information on nodal status involvement, with low morbidity. Within a few years, it became part of the standard treatment, at least for low and in…
Diagnosis and Treatment of Vulvo-Perineal Endometriosis: A Systematic Review Open
Objective: To describe the available knowledge on vulvo-perineal endometriosis including its diagnosis, clinical management and recurrence rate. Methods: We followed the PRISMA guidelines for Systematic Reviews and our study was prospectiv…
Hibernoma-like Changes and TFE3 Expression in Mesothelioma Mimicking TFE3-Translocation Renal Cell Carcinoma: A Diagnostic Pitfall Open
The long delay between asbestos exposure and the development of mesothelioma will likely result in an increased incidence of mesothelioma in our industrialized societies. Radiation therapy is another factor known to induce these tumors. We…
Experience With Medical Treatment of Cesarean Scar Ectopic Pregnancy (CSEP) With Local Ultrasound-Guided Injection of Methotrexate Open
Objective: Ectopic pregnancy within Cesarean section scars is a rare condition. Late diagnosis carries significant risk of bleeding with poor prognosis for survival. There is no consensus on the management of this type of pregnancy. Histor…
Hysteroscopic Resection for Missed Abortion: Feasibility, Operative Technique and Potential Benefit Compared to Curettage Open
Objective: To evaluate the feasibility of hysteroscopic resection (HsR) for primary surgical management of missed abortion. Reproductive outcomes and potential benefit of this technique will be compared to traditional dilatation and curett…
View article: Central Pathology Review in SENTIX, a Prospective Observational International Study on Sentinel Lymph Node Biopsy in Patients with Early-Stage Cervical Cancer (ENGOT-CX2)
Central Pathology Review in SENTIX, a Prospective Observational International Study on Sentinel Lymph Node Biopsy in Patients with Early-Stage Cervical Cancer (ENGOT-CX2) Open
The quality of pathological assessment is crucial for the safety of patients with cervical cancer if pelvic lymph node dissection is to be replaced by sentinel lymph node (SLN) biopsy. Central pathology review of SLN pathological ultrastag…
View article: Effect on surgical decisions: Ulipristal acetate as key player in Belgian phase <scp>IV</scp> registration trial
Effect on surgical decisions: Ulipristal acetate as key player in Belgian phase <span>IV</span> registration trial Open
Objective To observe alterations in surgical planning that were due to the use of ulipristal acetate ( UPA ) 5 mg daily for symptomatic uterine fibroids. Methods A prospective cohort trial involving women with symptomatic fibroids was unde…