Mathieu Pecqueux
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View article: Sarcopenia in Colorectal Cancer Surgery—Minimally Invasive vs. Open
Sarcopenia in Colorectal Cancer Surgery—Minimally Invasive vs. Open Open
Background Sarcopenia, characterized by loss of skeletal muscle mass and strength, is prevalent in patients undergoing treatment for colorectal cancer. Sarcopenia's prevalence in patients with cancer can reach up to 50% and is known to exa…
View article: Extracellular vesicles from pancreatic cancer and its tumour microenvironment promote increased Schwann cell migration
Extracellular vesicles from pancreatic cancer and its tumour microenvironment promote increased Schwann cell migration Open
Background Pancreatic ductal adenocarcinoma (PDAC) exhibits a high frequency of neural invasion (NI). Schwann cells (SCs) have been shown to be reprogrammed to facilitate cancer cell migration and invasion into nerves. Since extracellular …
View article: Nucleotide metabolism in cancer cells fuels a UDP-driven macrophage cross-talk, promoting immunosuppression and immunotherapy resistance
Nucleotide metabolism in cancer cells fuels a UDP-driven macrophage cross-talk, promoting immunosuppression and immunotherapy resistance Open
View article: Preoperative anaemia in distal pancreatectomy: a propensity-score matched analysis
Preoperative anaemia in distal pancreatectomy: a propensity-score matched analysis Open
View article: Preoperative IL-8 levels as prognostic indicators of overall survival: an extended follow-up in a prospective cohort with colorectal liver metastases
Preoperative IL-8 levels as prognostic indicators of overall survival: an extended follow-up in a prospective cohort with colorectal liver metastases Open
View article: Correction: COMPASS: deCOMPressing stomA and two-Stage elective resection vs. emergency reSection in patients with left-sided obstructive colon cancer
Correction: COMPASS: deCOMPressing stomA and two-Stage elective resection vs. emergency reSection in patients with left-sided obstructive colon cancer Open
View article: COMPASS: deCOMPressing stomA and two-Stage elective resection vs. emergency reSection in patients with left-sided obstructive colon cancer
COMPASS: deCOMPressing stomA and two-Stage elective resection vs. emergency reSection in patients with left-sided obstructive colon cancer Open
View article: Interleukin-8 is superior to CRP for the prediction of severe complications in a prospective cohort of patients undergoing major liver resection
Interleukin-8 is superior to CRP for the prediction of severe complications in a prospective cohort of patients undergoing major liver resection Open
View article: RAB27B expression in pancreatic cancer is predictive of poor survival but good response to chemotherapy
RAB27B expression in pancreatic cancer is predictive of poor survival but good response to chemotherapy Open
BACKGROUND: Pancreatic cancer is the 4th leading cause of cancer-related death with poor survival even after curative resection. RAB27A and RAB27B are key players in the exosome pathway where they play important roles in exosome secretion.…
View article: Plasma extracellular vesicle messenger RNA profiling identifies prognostic EV signature for non-invasive risk stratification for survival prediction of patients with pancreatic ductal adenocarcinoma
Plasma extracellular vesicle messenger RNA profiling identifies prognostic EV signature for non-invasive risk stratification for survival prediction of patients with pancreatic ductal adenocarcinoma Open
View article: The use and future perspective of Artificial Intelligence—A survey among German surgeons
The use and future perspective of Artificial Intelligence—A survey among German surgeons Open
Purpose Clinical abundance of artificial intelligence has increased significantly in the last decade. This survey aims to provide an overview of the current state of knowledge and acceptance of AI applications among surgeons in Germany. Me…
View article: Selective decontamination of the digestive tract in colorectal surgery reduces anastomotic leakage and costs: a propensity score analysis
Selective decontamination of the digestive tract in colorectal surgery reduces anastomotic leakage and costs: a propensity score analysis Open
View article: Short-term preoperative drainage is associated with improved postoperative outcomes compared to that of long-term biliary drainage in pancreatic surgery
Short-term preoperative drainage is associated with improved postoperative outcomes compared to that of long-term biliary drainage in pancreatic surgery Open
View article: Proteomic Analyses of Fibroblast- and Serum-Derived Exosomes Identify QSOX1 as a Marker for Non-invasive Detection of Colorectal Cancer
Proteomic Analyses of Fibroblast- and Serum-Derived Exosomes Identify QSOX1 as a Marker for Non-invasive Detection of Colorectal Cancer Open
The treatment of colorectal cancer (CRC) has improved during the last decades, but methods for crucial early diagnosis are yet to be developed. The influence of the tumour microenvironment on liquid biopsies for early cancer diagnostics ar…
View article: Expression of Glypican 3 Is an Independent Prognostic Biomarker in Primary Gastro-Esophageal Adenocarcinoma and Corresponding Serum Exosomes
Expression of Glypican 3 Is an Independent Prognostic Biomarker in Primary Gastro-Esophageal Adenocarcinoma and Corresponding Serum Exosomes Open
Exosomes are nano-sized membranous vesicles of endosomal origin that carry nucleic acids, lipids and proteins. The cargo of exosomes is cell origin specific and the release of these exosomes and uptake by an acceptor cell is seen as a vita…
View article: Inhibition of Six1 affects tumour invasion and the expression of cancer stem cell markers in pancreatic cancer
Inhibition of Six1 affects tumour invasion and the expression of cancer stem cell markers in pancreatic cancer Open
View article: A Comprehensive MicroRNA Expression Profile of Liver and Lung Metastases of Colorectal Cancer with Their Corresponding Host Tissue and Its Prognostic Impact on Survival
A Comprehensive MicroRNA Expression Profile of Liver and Lung Metastases of Colorectal Cancer with Their Corresponding Host Tissue and Its Prognostic Impact on Survival Open
MicroRNAs are small non-coding RNAs with a length of 18–25 nucleotides. They can regulate tumor invasion and metastasis by changing the expression and translation of their target mRNAs. Their expression is substantially altered in colorect…
View article: Free intraperitoneal tumor cells and outcome in gastric cancer patients: a systematic review and meta-analysis
Free intraperitoneal tumor cells and outcome in gastric cancer patients: a systematic review and meta-analysis Open
FITC oder positive peritoneal cytology is associated with poor survival and increased peritoneal recurrence in gastric cancer.
View article: Overexpression of <scp>SIX1</scp> is an independent prognostic marker in stage <scp>I</scp>–<scp>III</scp> colorectal cancer
Overexpression of <span>SIX1</span> is an independent prognostic marker in stage <span>I</span>–<span>III</span> colorectal cancer Open
Epithelial‐to‐mesenchymal transition (EMT) contributes significantly to tumor progression and metastasis. The assessment of EMT‐associated transcription factors could be a promising approach to identify biomarkers and potential therapeutic…