Mathilde Galais
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View article: Unbiased and comprehensive identification of virus-derived circular RNAs in a large range of viral species and families
Unbiased and comprehensive identification of virus-derived circular RNAs in a large range of viral species and families Open
Non-coding RNAs play a significant role in viral infection cycles, with recent attention focused on circular RNAs (circRNAs) originating from various viral families. Notably, these circRNAs have been associated with oncogenesis and alterat…
View article: Highly potent antiviral drug candidates targeting SARS-CoV-2 nsp3 and nsp5
Highly potent antiviral drug candidates targeting SARS-CoV-2 nsp3 and nsp5 Open
Faced with the emergence of three epidemics linked to a virus from the coronaviridæ family over the last 20 years (SARS-CoV in China in 2002, MERS-CoV in Arabia in 2012, and SARS- CoV-2 worldwide in 2019), the identification of new antivir…
View article: Unbiased and comprehensive identification of viral encoded circular RNAs in a large range of viral species and families
Unbiased and comprehensive identification of viral encoded circular RNAs in a large range of viral species and families Open
Non-coding RNAs play a significant role in viral infection cycles, with recent attention focused on circular RNAs (circRNAs) originating from various viral families. Notably, these circRNAs have been associated with oncogenesis and alterat…
View article: Ferulic acid derivatives block coronaviruses HCoV-229E and SARS-CoV-2 replication in vitro
Ferulic acid derivatives block coronaviruses HCoV-229E and SARS-CoV-2 replication in vitro Open
A novel coronavirus, SARS-CoV-2, emerged in China at the end of 2019 causing a large global outbreak. As treatments are of the utmost importance, drugs with broad anti-coronavirus activity embody a rich and rapid drug discovery landscape, …
View article: Role of the cellular factor CTCF in the regulation of bovine leukemia virus latency and three-dimensional chromatin organization
Role of the cellular factor CTCF in the regulation of bovine leukemia virus latency and three-dimensional chromatin organization Open
Bovine leukemia virus (BLV)-induced tumoral development is a multifactorial phenomenon that remains incompletely understood. Here, we highlight the critical role of the cellular CCCTC-binding factor (CTCF) both in the regulation of BLV tra…
View article: HIV-1 Env induces pexophagy and an oxidative stress leading to uninfected CD4<sup>+</sup> T cell death
HIV-1 Env induces pexophagy and an oxidative stress leading to uninfected CD4<sup>+</sup> T cell death Open
The immunodeficiency observed in HIV-1-infected patients is mainly due to uninfected bystander CD4+ T lymphocyte cell death. The viral envelope glycoproteins (Env), expressed at the surface of infected cells, play a key role in this proces…
View article: Implication of the cellular factor CTCF in the regulation of Bovine Leukemia Virus latency and tridimensional chromatin organization
Implication of the cellular factor CTCF in the regulation of Bovine Leukemia Virus latency and tridimensional chromatin organization Open
Bovine Leukemia Virus (BLV)-induced tumoral development is a multifactorial phenomenon which remains largely unelucidated. Here, we highlighted the critical role of the cellular CCCTC-binding factor (CTCF) both in the regulation of BLV tra…
View article: HIV-1 Env induces pexophagy and an oxidative stress leading to uninfected CD4<sup>+</sup> T cell death
HIV-1 Env induces pexophagy and an oxidative stress leading to uninfected CD4<sup>+</sup> T cell death Open
The immunodeficiency observed in HIV-1-infected patients is mainly due to uninfected bystander CD4+ T lymphocyte cell death. The viral envelope glycoproteins (Env), expressed at the surface of infected cells, play a key role in this proces…
View article: HIV-1 Env induces pexophagy and an oxidative stress leading to uninfected CD4 <sup>+</sup> T cell death
HIV-1 Env induces pexophagy and an oxidative stress leading to uninfected CD4 <sup>+</sup> T cell death Open
The immunodeficiency observed in HIV-1-infected patients is mainly due to uninfected bystander CD4+ T lymphocyte cell death. The viral envelope glycoproteins (Env), expressed at the surface of infected cells, play a key role in this proces…
View article: HIV-1 Env induces pexophagy and an oxidative stress leading to uninfected CD4<sup>+</sup> T cell death
HIV-1 Env induces pexophagy and an oxidative stress leading to uninfected CD4<sup>+</sup> T cell death Open
The immunodeficiency observed in HIV-1-infected patients is mainly due to uninfected bystander CD4+ T lymphocyte cell death. The viral envelope glycoproteins (Env), expressed at the surface of infected cells, play a key role in this proces…
View article: HIV-1 Env induces pexophagy and an oxidative stress leading to uninfected CD4+ T cell death
HIV-1 Env induces pexophagy and an oxidative stress leading to uninfected CD4+ T cell death Open
The immunodeficiency observed in HIV-1-infected patients is mainly due to uninfected bystander CD4+ T lymphocytes death. The viral envelope glycoproteins (Env), expressed at the surface of infected cells, play a key role in this process. E…
View article: HIV‐1 Vpr inhibits autophagy during the early steps of infection of CD4 T cells
HIV‐1 Vpr inhibits autophagy during the early steps of infection of CD4 T cells Open
Background information Autophagy is induced during HIV‐1 entry into CD4 T cells by the fusion of the membranes triggered by the gp41 envelope glycoprotein. This anti‐HIV‐1 mechanism is inhibited by the viral infectivity factor (Vif) neosyn…
View article: Implications of Transcriptional Interference and of the Cellular Factor CTCF in the Regulation of Bovine Leukemia Virus Expression
Implications of Transcriptional Interference and of the Cellular Factor CTCF in the Regulation of Bovine Leukemia Virus Expression Open
info:eu-repo/semantics/published