Mathis Heydtmann
YOU?
Author Swipe
View article: Genome-wide association study of antisocial personality disorder diagnostic criteria provides evidence for shared risk factors across disorders
Genome-wide association study of antisocial personality disorder diagnostic criteria provides evidence for shared risk factors across disorders Open
Introduction While progress has been made in determining the genetic basis of antisocial behaviour, little progress has been made for antisocial personality disorder (ASPD), a condition that often co-occurs with other psychiatric condition…
View article: SLC19A1 Genetic Variation Leads to Altered Thiamine Diphosphate Transport: Implications for the Risk of Developing Wernicke–Korsakoff’s Syndrome
SLC19A1 Genetic Variation Leads to Altered Thiamine Diphosphate Transport: Implications for the Risk of Developing Wernicke–Korsakoff’s Syndrome Open
Aims Wernicke–Korsakoff syndrome (WKS) is commonly associated with chronic alcohol misuse, a condition known to have multiple detrimental effects on thiamine metabolism. This study was conducted to identify genetic variants that may contri…
Guidelines on the use of liver biopsy in clinical practice from the British Society of Gastroenterology, the Royal College of Radiologists and the Royal College of Pathology Open
Liver biopsy is required when clinically important information about the diagnosis, prognosis or management of a patient cannot be obtained by safer means, or for research purposes. There are several approaches to liver biopsy but predomin…
Eight weeks of sofosbuvir/velpatasvir for genotype 3 hepatitis C in previously untreated patients with significant (F2/3) fibrosis Open
Summary Twelve weeks sofosbuvir/velpatasvir (SOF/VEL) is a highly effective pan‐genotypic regimen for hepatitis C. Phase 2 data suggest 8 weeks of treatment may be sufficient for previously untreated noncirrhotic patients with genotype 3 (…
Editorial: Baclofen in the Treatment of Alcohol Use Disorder Open
EDITORIAL article Front. Psychiatry, 15 May 2019Sec. Addictive Disorders Volume 10 - 2019 | https://doi.org/10.3389/fpsyt.2019.00338
Baclofen and the Alcohol Withdrawal Syndrome-A Short Review Open
The Alcohol Withdrawal Syndrome (AWS), which may occur with or without delirium, is a frequent consequence of sudden alcohol cessation in patients with moderate to severe Alcohol Dependence Syndrome (ADS). Withdrawal as a result of habitua…
The Use of Baclofen as a Treatment for Alcohol Use Disorder: A Clinical Practice Perspective Open
Alcohol use disorder (AUD) is a brain disorder associated with high rates of mortality and morbidity worldwide. Baclofen, a selective gamma-aminobutyric acid-B (GABA-B) receptor agonist, has emerged as a promising drug for AUD. The use of …
The Addition of Vitamin D Supplementation to Interferon and Ribavirin in the Treatment of Hepatitis C Virus Infection: A Randomised Double-Blind Placebo-Controlled Pilot Study Open
Background: Vitamin D is known to be involved in the immune response to hepatitis C virus infection and preliminary data suggests that supplementation may improve response to treatment with interferon and ribavirin. Methods:The ViaDUCT stu…
View article: Cohort Profile: The Hepatitis C Virus (HCV) Research UK Clinical Database and Biobank
Cohort Profile: The Hepatitis C Virus (HCV) Research UK Clinical Database and Biobank Open
Why was the cohort set up?Hepatitis C is a blood-borne virus that causes scarring and inflammation of the liver.1 The virus is also associated with extrahepatic disease, including non Hodgkins lymphoma,2 renal disorders3 and, probably, car…
The SCottish Alcoholic Liver disease Evaluation: A Population-Level Matched Cohort Study of Hospital-Based Costs, 1991-2011 Open
Studies assessing the costs of alcoholic liver disease are lacking. We aimed to calculate the costs of hospitalisations before and after diagnosis compared to population controls matched by age, sex and socio-economic deprivation. We aimed…