Matias Vested
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View article: Avoidance versus use of neuromuscular blocking agents for optimizing video laryngoscopy‐assisted tracheal intubation: A protocol for a systematic review with meta‐analysis and trial sequential analysis
Avoidance versus use of neuromuscular blocking agents for optimizing video laryngoscopy‐assisted tracheal intubation: A protocol for a systematic review with meta‐analysis and trial sequential analysis Open
Background Both the European Society of Anaesthesiology and Intensive Care and the Difficult Airway Society recommend the use of neuromuscular blocking agents (NMBAs) to facilitate tracheal intubation and to reduce the risk of complication…
View article: Intubating conditions during rapid sequence induction with either rocuronium or suxamethonium in elderly patients. A randomised study
Intubating conditions during rapid sequence induction with either rocuronium or suxamethonium in elderly patients. A randomised study Open
Background During rapid sequence induction, either rocuronium 1.0 mg kg −1 or suxamethonium 1.0 mg kg −1 can be administered to facilitate endotracheal intubation. We hypothezised that rocuronium provided a larger proportion of excellent i…
View article: Shortened time to neuromuscular recovery with lower doses of rocuronium in elderly patients
Shortened time to neuromuscular recovery with lower doses of rocuronium in elderly patients Open
INTRODUCTION. The effect of neuromuscular blocking agents may be reversed by administration of neostigmine, when two twitches are present using train-of-four (TOF) stimulation. However, in elderly patients, limited data are available about…
View article: Onset time, duration of action, and intubating conditions after mivacurium in elderly and younger patients
Onset time, duration of action, and intubating conditions after mivacurium in elderly and younger patients Open
Background The neuromuscular blocking agent mivacurium can be used during anesthesia to facilitate tracheal intubation. Data on onset time, duration of action, and effect on intubating conditions in patients 80 years and older are however …
View article: Effects of avoidance versus use of neuromuscular blocking agents for facilitation of tracheal intubation in children and infants: a protocol for a systematic review, meta‐analysis and trial sequential analysis
Effects of avoidance versus use of neuromuscular blocking agents for facilitation of tracheal intubation in children and infants: a protocol for a systematic review, meta‐analysis and trial sequential analysis Open
Background The European Society of Anesthesiology and Intensive Care recommends the use of neuromuscular blocking agents (NMBA) in adults, to facilitate tracheal intubation and reduce its associated complications. Children who undergo trac…
View article: Prolonged duration of action of suxamethonium in pregnant and postpartum patients: A registry study
Prolonged duration of action of suxamethonium in pregnant and postpartum patients: A registry study Open
Background Suxamethonium is hydrolysed by butyrylcholinesterase (BChE) and a low BChE activity can result in a prolonged duration of action of suxamethonium. The BChE activity is reduced during pregnancy and postpartum period by up to 33%.…
View article: Good clinical research practice (<scp>GCRP</scp>) in pharmacodynamic studies of neuromuscular blocking agents <scp>III</scp>: The 2023 Geneva revision
Good clinical research practice (<span>GCRP</span>) in pharmacodynamic studies of neuromuscular blocking agents <span>III</span>: The 2023 Geneva revision Open
The set of guidelines for good clinical research practice in pharmacodynamic studies of neuromuscular blocking agents was developed following an international consensus conference in Copenhagen in 1996 (Viby‐Mogensen et al., Acta Anaesthes…
View article: Collaboration for Evidence‐based Practice and Research in Anaesthesia (<scp>CEPRA</scp>): A consortium initiative for perioperative research
Collaboration for Evidence‐based Practice and Research in Anaesthesia (<span>CEPRA</span>): A consortium initiative for perioperative research Open
Evidence in perioperative care is insufficient. There is an urgent need for large perioperative research programmes, including pragmatic randomised trials, testing daily clinical treatments and unanswered question, thereby providing solid …
View article: Comparison of onset time, duration of action, and intubating conditions after cisatracurium 0.15 mg/kg in young and elderly patients
Comparison of onset time, duration of action, and intubating conditions after cisatracurium 0.15 mg/kg in young and elderly patients Open
Introduction Tracheal intubation during anesthesia can be facilitated by the neuromuscular blocking agent cisatracurium. However, limited data exists about onset time, duration of action and effect on intubating conditions in elderly patie…
View article: Rocuronium 0.3 or 0.9 mg/kg comparing onset time, duration of action, and intubating conditions in patients 80 years and older: A randomized study
Rocuronium 0.3 or 0.9 mg/kg comparing onset time, duration of action, and intubating conditions in patients 80 years and older: A randomized study Open
Background Limited data exist about the optimal dose of rocuronium for intubation in elderly patients. We hypothesized that rocuronium 0.9 mg/kg would lead to a shorter onset time than 0.3 mg/kg in patients above 80 years. Methods Thirty‐f…
View article: Resistance towards nondepolarising muscle relaxants
Resistance towards nondepolarising muscle relaxants Open
A prolonged onset time should be suspected in patients with thermal injury and Duchenne's muscular dystrophy. Further, evidence supports a prolonged onset time in patients with infection, oculopharyngeal muscular dystrophy, congenital hear…