Mats E. Pettersson
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View article: Adaptive introgression from Pacific herring to Atlantic herring in the brackish Baltic Sea
Adaptive introgression from Pacific herring to Atlantic herring in the brackish Baltic Sea Open
The genomic era has revealed that interspecific gene flow can play an important role in adaptive evolution. Here, we report a striking case of adaptive introgression from Pacific into Atlantic herring following the colonization of the brac…
View article: Pathological and bacteriological findings in sows, finisher pigs, and piglets, being culled for lameness
Pathological and bacteriological findings in sows, finisher pigs, and piglets, being culled for lameness Open
View article: Genetic Adaptation to Brackish Water and Spawning Season in European Cisco
Genetic Adaptation to Brackish Water and Spawning Season in European Cisco Open
How species adapt to diverse environmental conditions is essential for understanding evolution and the maintenance of biodiversity. The European cisco ( Coregonus albula ) is a salmonid that occurs in both fresh and brackish water, and thi…
View article: Whole Genome Sequencing Reveals How Plasticity and Genetic Differentiation Underlie Sympatric Morphs of Arctic Charr
Whole Genome Sequencing Reveals How Plasticity and Genetic Differentiation Underlie Sympatric Morphs of Arctic Charr Open
Salmonids have a remarkable ability to form sympatric morphs after postglacial colonisation of freshwater lakes. These morphs often differ in morphology, feeding and spawning behaviour. Here, we explored the genetic basis of morph differen…
View article: Unheralded high MHC Class II polymorphism in the abundant Atlantic herring resolved by long-read sequencing
Unheralded high MHC Class II polymorphism in the abundant Atlantic herring resolved by long-read sequencing Open
Major Histocompatibility Complex (MHC) genes are the most polymorphic in vertebrate genomes due to their important function of presenting a diversity of peptides from pathogens to initiate an adaptive immune response. Here, we have charact…
View article: Genome variation in three Anthophora bee species reflects divergent demographic histories
Genome variation in three Anthophora bee species reflects divergent demographic histories Open
View article: Experimental Results of Local Backprojection for Monostatic THz SAR Imaging
Experimental Results of Local Backprojection for Monostatic THz SAR Imaging Open
The use of THz frequencies has enabled the opportunity to perform synthetic-aperture radar (SAR) imaging at the sub-mm level. It is of great interest for applications where high-resolution remote sensing in short range is required. However…
View article: Whole genome sequencing reveals how plasticity and genetic differentiation underlie sympatric morphs of Arctic charr
Whole genome sequencing reveals how plasticity and genetic differentiation underlie sympatric morphs of Arctic charr Open
Salmonids have a remarkable ability to form sympatric morphs after postglacial colonization of freshwater lakes. These morphs often exhibit differences in morphology, feeding, and spawning behaviour. Here we explore the genetics of morph d…
View article: Evolution of fast-growing piscivorous herring in the young Baltic Sea
Evolution of fast-growing piscivorous herring in the young Baltic Sea Open
View article: Molecular basis of attack patterns during cock fighting
Molecular basis of attack patterns during cock fighting Open
Aggression is an essential animal behaviour for survival, particularly in situations where fighting cannot be avoided. In such situations, the choice of attack pattern (i.e. biting, charging, or defending) is critical. However, the molecul…
View article: The origin and maintenance of supergenes contributing to ecological adaptation in Atlantic herring
The origin and maintenance of supergenes contributing to ecological adaptation in Atlantic herring Open
View article: THz SAR Bistatic 3D Global Backprojection Algorithm with Phase Control
THz SAR Bistatic 3D Global Backprojection Algorithm with Phase Control Open
Exploration of THz frequencies has enabled new applications in the areas, where high-resolution short-range remote sensing is of great interest. At the high frequency ranges like THz or sub-THz, synthetic aperture radar (SAR) image formati…
View article: Genetic Stock Identification Reveals Mismatches Between Management Areas and Population Genetic Structure in a Migratory Pelagic Fish
Genetic Stock Identification Reveals Mismatches Between Management Areas and Population Genetic Structure in a Migratory Pelagic Fish Open
Sustainable fisheries management is important for the continued harvest of the world's marine resources, especially as they are increasingly challenged by a range of climatic and anthropogenic factors. One of the pillars of sustainable fis…
View article: Unraveling the Genetics of Shared Clinical and Serological Manifestations in Patients With Systemic Inflammatory Autoimmune Diseases
Unraveling the Genetics of Shared Clinical and Serological Manifestations in Patients With Systemic Inflammatory Autoimmune Diseases Open
Objective Systemic inflammatory autoimmune diseases (SIADs) such as systemic lupus erythematosus (SLE), primary Sjögren disease (pSS), and idiopathic inflammatory myopathies (myositis) are complex conditions characterized by shared circula…
View article: Limited Parallelism in Genetic Adaptation to Brackish Water Bodies in European Sprat and Atlantic Herring
Limited Parallelism in Genetic Adaptation to Brackish Water Bodies in European Sprat and Atlantic Herring Open
The European sprat is a small plankton-feeding clupeid present in the northeastern Atlantic Ocean, in the Mediterranean Sea, and in the brackish Baltic Sea and Black Sea. This species is the target of a major fishery and, therefore, an acc…
View article: Copy number variation and elevated genetic diversity at immune trait loci in Atlantic and Pacific herring
Copy number variation and elevated genetic diversity at immune trait loci in Atlantic and Pacific herring Open
Background Genome-wide comparisons of populations are widely used to explore the patterns of nucleotide diversity and sequence divergence to provide knowledge on how natural selection and genetic drift affect the genome. In this study we h…
View article: Contrasting segregation patterns among endogenous retroviruses across the koala population
Contrasting segregation patterns among endogenous retroviruses across the koala population Open
View article: Conservation of Affinity Rather Than Sequence Underlies a Dynamic Evolution of the Motif-Mediated p53/MDM2 Interaction in Ray-Finned Fishes
Conservation of Affinity Rather Than Sequence Underlies a Dynamic Evolution of the Motif-Mediated p53/MDM2 Interaction in Ray-Finned Fishes Open
The transcription factor and cell cycle regulator p53 is marked for degradation by the ubiquitin ligase MDM2. The interaction between these 2 proteins is mediated by a conserved binding motif in the disordered p53 transactivation domain (p…
View article: Contrasting segregation patterns among endogenous retroviruses across the koala population
Contrasting segregation patterns among endogenous retroviruses across the koala population Open
Koalas ( Phascolarctos cinereus ) are subject to retroviral infections by the koala retrovirus (KoRV), resulting in accumulation of heritable endogenous KoRV in the koala germline. Like other vertebrates, koalas have experienced a history …
View article: CNSC-40. HARNESSING EVOLUTIONARY CONSTRAINT IDENTIFIES POTENTIAL NON-CODING DRIVERS IN BRAIN TUMORS
CNSC-40. HARNESSING EVOLUTIONARY CONSTRAINT IDENTIFIES POTENTIAL NON-CODING DRIVERS IN BRAIN TUMORS Open
The somatic mutational landscape of brain tumors has primarily focused on coding mutations for driver gene discovery. Non-coding mutations can drive cancer by targeting regulatory elements and be valuable biomarkers and therapeutic targets…
View article: How Fish Population Genomics Can Promote Sustainable Fisheries: A Road Map
How Fish Population Genomics Can Promote Sustainable Fisheries: A Road Map Open
Maintenance of genetic diversity in marine fishes targeted by commercial fishing is a grand challenge for the future. Most of these species are abundant and therefore important for marine ecosystems and food security. Here, we present a ro…
View article: Copy number variation and elevated genetic diversity at immune trait loci in Atlantic and Pacific herring
Copy number variation and elevated genetic diversity at immune trait loci in Atlantic and Pacific herring Open
Atlantic and Pacific herring are sister species that diverged about 2 million years ago. Here we describe a genome comparison of the two species that reveal high genome-wide differentiation as expected for two distinct species but with isl…
View article: The origin and maintenance of supergenes contributing to ecological adaptation in Atlantic herring
The origin and maintenance of supergenes contributing to ecological adaptation in Atlantic herring Open
Chromosomal inversions are associated with local adaptation in many species. However, questions regarding how they are formed, maintained and impact various other evolutionary processes remain elusive. Here, using a large genomic dataset o…
View article: Low mutation rate in epaulette sharks is consistent with a slow rate of evolution in sharks
Low mutation rate in epaulette sharks is consistent with a slow rate of evolution in sharks Open
View article: Conservation of affinity rather than sequence underlies a dynamic evolution of the motif-mediated p53/MDM2 interaction in teleosts
Conservation of affinity rather than sequence underlies a dynamic evolution of the motif-mediated p53/MDM2 interaction in teleosts Open
The transcription factor and cell cycle regulator p53 is marked for degradation by the ubiquitin ligase MDM2. The interaction between these two proteins is mediated by a conserved binding motif in the disordered p53 transactivation domain …
View article: Using evolutionary constraint to define novel candidate driver genes in medulloblastoma
Using evolutionary constraint to define novel candidate driver genes in medulloblastoma Open
Current knowledge of cancer genomics remains biased against noncoding mutations. To systematically search for regulatory noncoding mutations, we assessed mutations in conserved positions in the genome under the assumption that these are mo…
View article: The genomic basis and environmental correlates of local adaptation in the Atlantic horse mackerel ( <i>Trachurus trachurus</i> )
The genomic basis and environmental correlates of local adaptation in the Atlantic horse mackerel ( <i>Trachurus trachurus</i> ) Open
Understanding how populations adapt to their environment is increasingly important to prevent biodiversity loss due to overexploitation and climate change. Here we studied the population structure and genetic basis of local adaptation of A…
View article: A Long-Standing Hybrid Population Between Pacific and Atlantic Herring in a Subarctic Fjord of Norway
A Long-Standing Hybrid Population Between Pacific and Atlantic Herring in a Subarctic Fjord of Norway Open
Atlantic herring (Clupea harengus) and Pacific herring (C. pallasii) are sister species that split from a common ancestor about 2 million years ago. Balsfjord, a subarctic fjord in Northern Norway, harbors an outpost population of Pacific …
View article: Supplementary Table 5 from <i>SETD2</i> Is Recurrently Mutated in Whole-Exome Sequenced Canine Osteosarcoma
Supplementary Table 5 from <i>SETD2</i> Is Recurrently Mutated in Whole-Exome Sequenced Canine Osteosarcoma Open
File contains genes that have focal somatic copy number deletions.
View article: Supplementary Table 14 from <i>SETD2</i> Is Recurrently Mutated in Whole-Exome Sequenced Canine Osteosarcoma
Supplementary Table 14 from <i>SETD2</i> Is Recurrently Mutated in Whole-Exome Sequenced Canine Osteosarcoma Open
File contains list of GISTIC Defined Recurrent SCNA genes that overlap between Humans and Dogs.