Matt T. Oberdier
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View article: Sudden cardiac arrest prediction via deep learning electrocardiogram analysis
Sudden cardiac arrest prediction via deep learning electrocardiogram analysis Open
Aims Sudden cardiac arrest (SCA) is a commonly fatal event that often occurs without prior indications. To improve outcomes and enable preventative strategies, the electrocardiogram (ECG) in conjunction with deep learning was explored as a…
View article: RED BLOOD CELL DISTRIBUTION WIDTH: FURTHER INSIGHTS
RED BLOOD CELL DISTRIBUTION WIDTH: FURTHER INSIGHTS Open
Red blood cell distribution width (RDW) measures erythrocyte size variability and strongly predicts cardiovascular disease (CVD) morbidity and mortality. Our prior cross-sectional analysis showed that inflammation, metabolic rate, and body…
View article: Survival and Neurologic Outcomes From Pharmacologic Peptide Administration During Cardiopulmonary Resuscitation of Pulseless Electrical Activity
Survival and Neurologic Outcomes From Pharmacologic Peptide Administration During Cardiopulmonary Resuscitation of Pulseless Electrical Activity Open
Background Outcomes from cardiopulmonary resuscitation (CPR) following sudden cardiac arrest are suboptimal. Postresuscitation targeted temperature management has been shown to have benefit in subjects with sudden cardiac arrest due to ven…
View article: Comparison Between a Single-Lead ECG Garment Device and a Holter Monitor: A Signal Quality Assessment
Comparison Between a Single-Lead ECG Garment Device and a Holter Monitor: A Signal Quality Assessment Open
Wearable electronics are increasingly common and useful as health monitoring devices, many of which feature the ability to record a single-lead electrocardiogram (ECG). However, recording the ECG commonly requires the user to touch the dev…
View article: RED BLOOD CELL DISTRIBUTION WIDTH: WHAT CAN IT TELL US?
RED BLOOD CELL DISTRIBUTION WIDTH: WHAT CAN IT TELL US? Open
Red blood cell distribution width (RDW), a measure of red blood cell size variability used in evaluating anemia, has been found to predict cardiovascular disease (CVD) morbidity and mortality. RDW increases with age, but the determinants o…
View article: Electrocardiogram Monitoring Wearable Devices and Artificial-Intelligence-Enabled Diagnostic Capabilities: A Review
Electrocardiogram Monitoring Wearable Devices and Artificial-Intelligence-Enabled Diagnostic Capabilities: A Review Open
Worldwide, population aging and unhealthy lifestyles have increased the incidence of high-risk health conditions such as cardiovascular diseases, sleep apnea, and other conditions. Recently, to facilitate early identification and diagnosis…
View article: A cell-penetrating PHLPP peptide improves cardiac arrest survival in murine and swine models
A cell-penetrating PHLPP peptide improves cardiac arrest survival in murine and swine models Open
Out-of-hospital cardiac arrest is a leading cause of death in the US, with a mortality rate over 90%. Preclinical studies demonstrate that cooling during cardiopulmonary resuscitation (CPR) is highly beneficial, but can be challenging to i…
View article: Algorithm for Mobile Platform-Based Real-Time QRS Detection
Algorithm for Mobile Platform-Based Real-Time QRS Detection Open
Recent advancements in smart, wearable technologies have allowed the detection of various medical conditions. In particular, continuous collection and real-time analysis of electrocardiogram data have enabled the early identification of pa…
View article: Reduced motion external defibrillation: Reduced subject motion with equivalent defibrillation efficiency validated in swine
Reduced motion external defibrillation: Reduced subject motion with equivalent defibrillation efficiency validated in swine Open
View article: Closed cranial window rodent model for investigating hemodynamic response to elevated intracranial pressure
Closed cranial window rodent model for investigating hemodynamic response to elevated intracranial pressure Open
Background Elevated intracranial pressure (ICP) occurs in several physiological and pathological conditions, yet long‐term sequellae are not common, which implies that blood flow is preserved above ischemic thresholds. Methods This pilot s…
View article: Sex Differences in Longitudinal Determinants of Carotid Intima Medial Thickening With Aging in a Community‐Dwelling Population: The Baltimore Longitudinal Study on Aging
Sex Differences in Longitudinal Determinants of Carotid Intima Medial Thickening With Aging in a Community‐Dwelling Population: The Baltimore Longitudinal Study on Aging Open
Background Common carotid intima medial thickness (IMT) increases with aging. However, the longitudinal association between IMT and other age‐associated hemodynamic alterations in men and in women are not fully explored. Methods and Result…
View article: CPR and ECMO: The Next Frontier
CPR and ECMO: The Next Frontier Open
Cardiopulmonary resuscitation (CPR) is a first-line therapy for sudden cardiac arrest, while extracorporeal membrane oxygenation (ECMO) has traditionally been used as a means of countering circulatory failure. However, new advances dictate…
View article: Subclinical Longitudinal Change in Ankle‐Brachial Index With Aging in a Community‐Dwelling Population Is Associated With Central Arterial Stiffening
Subclinical Longitudinal Change in Ankle‐Brachial Index With Aging in a Community‐Dwelling Population Is Associated With Central Arterial Stiffening Open
Background Aging is associated with a modest decline in ankle‐brachial index ( ABI ); however, the underpinnings of this decline are not fully understood. The greater systolic ankle than brachial blood pressure, a normal ABI implies, is pa…
View article: Lower Mitochondrial Energy Production of the Thigh Muscles in Patients With Low‐Normal Ankle‐Brachial Index
Lower Mitochondrial Energy Production of the Thigh Muscles in Patients With Low‐Normal Ankle‐Brachial Index Open
Background Lower muscle mitochondrial energy production may contribute to impaired walking endurance in patients with peripheral arterial disease. A borderline ankle‐brachial index (ABI) of 0.91 to 1.10 is associated with poorer walking en…