Mattan Levi
YOU?
Author Swipe
View article: The Synergic Effect of Tubal Endometriosis and Women’s Aging on Fallopian Tube Function: Insights from a 3D Mechanical Model
The Synergic Effect of Tubal Endometriosis and Women’s Aging on Fallopian Tube Function: Insights from a 3D Mechanical Model Open
The fallopian tubes are essential for human fertility, facilitating the movement of sperm and oocytes to the fertilization site and transporting fertilized oocytes to the uterus. Infertility can result from changes in the fallopian tubes d…
View article: Perinatal Outcomes of Singleton, Twin and Triplet Gestations after Oocyte Donation: A Retrospective, Population-Based Cohort Analysis
Perinatal Outcomes of Singleton, Twin and Triplet Gestations after Oocyte Donation: A Retrospective, Population-Based Cohort Analysis Open
Background/Objectives: Although high live birth rates are associated with oocyte donation (OD), these pregnancies are associated with increased obstetric and perinatal risks. This study evaluated maternal and neonatal risks after OD compar…
View article: P-724 Long-term health outcomes of 19 years follow-up of mothers conceived after oocyte donation based on the registry of a large healthcare organization
P-724 Long-term health outcomes of 19 years follow-up of mothers conceived after oocyte donation based on the registry of a large healthcare organization Open
Study question Short term outcomes of oocyte donation (OD) pregnancies are known. Yet, long term effect of OD pregnancies on mother’s health are lacking. Summary answer Comparing women after OD pregnancies to spontaneous pregnancies or nul…
View article: P-043 Preliminary clinical outcome using the Q300™ device in a reproductive laboratory environment
P-043 Preliminary clinical outcome using the Q300™ device in a reproductive laboratory environment Open
Study question How does the Q300™ Device impact clinical outcomes in a reproductive laboratory environment compared to established standards? Summary answer The device showed favorable clinical outcomes and was user-friendly. More research…
View article: Two types of cleavage, from zygote to three cells, result in different clinical outcomes and should be treated differently
Two types of cleavage, from zygote to three cells, result in different clinical outcomes and should be treated differently Open
Research Question What is the utilization rate of embryos that exert inadequate zygote cleavage into three daughter cells? Design This study used a retrospective dataset from a single IVF Unit. A total of 3,060 embryos from 1,811 fresh IVF…
View article: Oocyte retrieval in social fertility preservation: challenging traditional beliefs on gonadotropin dosing and follicular size
Oocyte retrieval in social fertility preservation: challenging traditional beliefs on gonadotropin dosing and follicular size Open
Objectives To investigate treatment approaches for fertility preservation patients, with a focus on timing of oocyte retrieval, and to determine whether their characteristics differ from those of other IVF patients. Additionally, to evalua…
View article: Evaluation of women’s aging influence on sperm passage inside the fallopian tube using 3D dynamic mechanical modeling
Evaluation of women’s aging influence on sperm passage inside the fallopian tube using 3D dynamic mechanical modeling Open
The fallopian tubes play an important role in human fertility by facilitating the spermatozoa passage to the oocyte as well as later actively facilitating the fertilized oocyte transportation to the uterus cavity. The fallopian tubes under…
View article: Stain-Free Sperm Analysis and Selection for Intracytoplasmic Sperm Injection Complying with WHO Strict Normal Criteria
Stain-Free Sperm Analysis and Selection for Intracytoplasmic Sperm Injection Complying with WHO Strict Normal Criteria Open
This multi-center study evaluated a novel microscope system capable of quantitative phase microscopy (QPM) for label-free sperm-cell selection for intracytoplasmic sperm injection (ICSI). Seventy-three patients were enrolled in four in vit…
View article: Novel non-toxic technology of sperm selection for ICSI comply with WHO strict normal criteria for stained sperm cells
Novel non-toxic technology of sperm selection for ICSI comply with WHO strict normal criteria for stained sperm cells Open
The authors have requested that this preprint be removed from Research Square.
View article: Location Prediction of Sperm Cells Using Long Short‐Term Memory Networks
Location Prediction of Sperm Cells Using Long Short‐Term Memory Networks Open
Intracytoplasmic sperm injection (ICSI) requires precise selection of a single sperm cell in a dish to be injected into an oocyte. This task is challenging due to high sperm velocity, collision with other sperm cells, and changes in the im…
View article: P-204 The pattern of the zygote cleavage to three cells must be considered before embryo transfer
P-204 The pattern of the zygote cleavage to three cells must be considered before embryo transfer Open
Study question What is the clinical outcome of instant irregular cleavage (IDC) from zygote to three cells? Summary answer IDC embryos, did not develop to blastocysts and did not acieve pregnancy; FC embryos that reached blastocyst stage e…
View article: Dynamic 3D Modeling for Human Sperm Motility through the Female Cervical Canal and Uterine Cavity to Predict Sperm Chance of Reaching the Oocyte
Dynamic 3D Modeling for Human Sperm Motility through the Female Cervical Canal and Uterine Cavity to Predict Sperm Chance of Reaching the Oocyte Open
Sperm motility in the female genital tract is a key factor in the natural selection of competent cells that will produce a healthy offspring. We created a dynamic three-dimensional (3D) mechanical model of human sperm cells swimming inside…
View article: Prediction of Sperm Progression in Three Dimensions Using Rapid Optical Imaging and Dynamic Mechanical Modeling
Prediction of Sperm Progression in Three Dimensions Using Rapid Optical Imaging and Dynamic Mechanical Modeling Open
We present a multidisciplinary approach for predicting how sperm cells with various morphologies swim in three-dimensions (3D), from milliseconds to much longer time scales at spatial resolutions of less than half a micron. We created the …
View article: Tumor Lymphocyte Infiltration Is Correlated with a Favorable Tumor Regression Grade after Neoadjuvant Treatment for Esophageal Adenocarcinoma
Tumor Lymphocyte Infiltration Is Correlated with a Favorable Tumor Regression Grade after Neoadjuvant Treatment for Esophageal Adenocarcinoma Open
(1) Background: We aimed to explore the association between neoadjuvant treatment, tumor-infiltrating immune lymphocyte (TIL), and tumor-associated macrophage (TAM) and survival in patients with esophageal adenocarcinoma. (2) Methods: Pati…
View article: Irinotecan (CPT-11) Treatment Induces Mild Gonadotoxicity
Irinotecan (CPT-11) Treatment Induces Mild Gonadotoxicity Open
Background: Gonadal toxicity following chemotherapy is an important issue among the population of young cancer survivors. The inhibitor of DNA topoisomerase I, irinotecan (CPT-11), is widely used for several cancer types. However, little i…
View article: Pretreatment with gonadotropin-releasing hormone antagonist protects against chemotherapy-induced testicular damage in mice
Pretreatment with gonadotropin-releasing hormone antagonist protects against chemotherapy-induced testicular damage in mice Open
Background: Testicular toxicity following chemotherapy is of increasing importance with the continuous improvement of survival rates. Gonadotropin-releasing hormone (GnRH) was suggested to protect testis against such toxicity; however, its…
View article: Simultaneous Morphology, Motility, and Fragmentation Analysis of Live Individual Sperm Cells for Male Fertility Evaluation
Simultaneous Morphology, Motility, and Fragmentation Analysis of Live Individual Sperm Cells for Male Fertility Evaluation Open
A new technique for sperm analysis is presented, measuring DNA fragmentation, morphology with virtual staining, and motility, all three criteria on the same individual unstained live cell. The method relies on quantitative stain‐free inter…
View article: Prediction of sperm progression in three dimensions using rapid optical imaging and dynamic mechanical modeling
Prediction of sperm progression in three dimensions using rapid optical imaging and dynamic mechanical modeling Open
We present a multidisciplinary approach for predicting how sperm cells with various morphologies swim in three-dimensions (3D), over time scales of milliseconds to hours at spatial resolutions of less than half a micron. We created the spe…
View article: Simultaneous Morphology, Motility and Fragmentation Analysis of Live Individual Sperm Cells for Male Fertility Evaluation
Simultaneous Morphology, Motility and Fragmentation Analysis of Live Individual Sperm Cells for Male Fertility Evaluation Open
We present a new technique for sperm analysis on individual unstained live cells, measuring DNA fragmentation, morphology with virtual staining, and motility. The method relies on quantitative stain-free interferometric imaging and deep-le…
View article: Anti-HER2/neu Antibody Reduces Chemotherapy-Induced Ovarian Toxicity—From Bench to Bedside
Anti-HER2/neu Antibody Reduces Chemotherapy-Induced Ovarian Toxicity—From Bench to Bedside Open
Background: Trastuzumab, a humanized anti-human epidermal growth factor receptor 2 (HER2/neu) antibody, is considered a standard treatment in addition to chemotherapy in the adjuvant setting for HER2/neu-positive breast cancer, yet its imp…
View article: Cancer During Pregnancy: The Role of Vascular Toxicity in Chemotherapy-Induced Placental Toxicity
Cancer During Pregnancy: The Role of Vascular Toxicity in Chemotherapy-Induced Placental Toxicity Open
Breast cancer is diagnosed in ~0.3% of pregnant women. Studies that have addressed gestational and neonatal outcomes of chemotherapy during pregnancy have demonstrated increased gestational complications including preeclampsia and intraute…
View article: Holographic virtual staining of individual biological cells
Holographic virtual staining of individual biological cells Open
Significance We present a method for virtual staining for morphological analysis of individual biological cells based on stain-free digital holography, allowing clinicians and biologists to visualize and analyze the cells as if they have b…
View article: Treosulfan induces distinctive gonadal toxicity compared with busulfan
Treosulfan induces distinctive gonadal toxicity compared with busulfan Open
Treosulfan (L-treitol-1,4-bis-methanesulfonate) has been increasingly incorporated as a main conditioning protocol for hematopoietic stem cell transplantation in pediatric malignant and non-malignant diseases. Treosulfan presents lower tox…
View article: Premature ovarian aging in <i>BRCA</i> carriers: a prototype of systemic precocious aging?
Premature ovarian aging in <i>BRCA</i> carriers: a prototype of systemic precocious aging? Open
Our results suggest a link between BRCA mutation, accelerated ovarian aging and systemic aging-related pathophysiology.
View article: Automated analysis of individual sperm cells using stain‐free interferometric phase microscopy and machine learning
Automated analysis of individual sperm cells using stain‐free interferometric phase microscopy and machine learning Open
Currently, the delicate process of selecting sperm cells to be used for in vitro fertilization (IVF) is still based on the subjective, qualitative analysis of experienced clinicians using non‐quantitative optical microscopy techniques. In …
View article: Can molecular profiling enhance radiotherapy? Impact of personalized targeted gold nanoparticles on radiosensitivity and imaging of adenoid cystic carcinoma
Can molecular profiling enhance radiotherapy? Impact of personalized targeted gold nanoparticles on radiosensitivity and imaging of adenoid cystic carcinoma Open
Personalized molecular profiling has an established role in selection of treatment for metastatic disease; however, its role in improving radiosensitivity and functional imaging has not been evaluated. In the current study, we examined mol…
View article: Growth Plate Lesions of Fattening Bulls
Growth Plate Lesions of Fattening Bulls Open
Lameness related to growth plate lesions is an important problem in the beef industry. This article describes the macroscopic and microscopic lesions in the distal metatarsal physis of bulls from an association of farmers in northeastern I…
View article: The impact of oxaliplatin on the gonads: from bedside to the bench
The impact of oxaliplatin on the gonads: from bedside to the bench Open
This study was supported by the Israeli Science Foundation (ISF) grant 13-1816 (I.B.-A.). There is no conflict of interest.