Matteo Ramazzotti
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View article: Methylomic Signature and Epigenetic Damage Modulation of Bronte Pistachio (Pistacia vera L.) Hydrophilic Extract in Differentiated CaCo-2 Cells
Methylomic Signature and Epigenetic Damage Modulation of Bronte Pistachio (Pistacia vera L.) Hydrophilic Extract in Differentiated CaCo-2 Cells Open
Background/Objectives: Nutrigenomics explores how dietary components influence genome function, especially via epigenetic mechanisms like DNA methylation. A key challenge is identifying healthy food-derived molecules capable of counteracti…
View article: Compositional and Functional Disparities in the Breast Oncobiome Between Patients Living in Urban or Rural Areas
Compositional and Functional Disparities in the Breast Oncobiome Between Patients Living in Urban or Rural Areas Open
Background/Objectives: Breast cancer (BC) is the leading cause of cancer incidence and mortality among women and the recent identification of a resident mammary microbiota has highlighted its potential role in breast carcinogenesis. Given …
View article: Testing the limits of short-reads metagenomic classifications programs in wastewater treating microbial communities
Testing the limits of short-reads metagenomic classifications programs in wastewater treating microbial communities Open
Biological wastewater treatment processes, such as activated sludge (AS) and aerobic granular sludge (AGS), have proven to be crucial systems for achieving both efficient waste purification and the recovery of valuable resources like poly-…
View article: Testing the limits of short-reads metagenomic classifications programs in waste water treating microbial communities
Testing the limits of short-reads metagenomic classifications programs in waste water treating microbial communities Open
Biological wastewater treatment processes, such as activated sludge (AS) and aerobic granular sludge (AGS), have proven to be crucial systems for achieving both efficient waste purification and the recovery of valuable resources like poly-…
View article: CircoTax: a novel circular representation of differentially abundant microbial ranks
CircoTax: a novel circular representation of differentially abundant microbial ranks Open
One of the most relevant and widely used applications of NGS-based microbial abundance analysis is the discovery of taxa that appear as differentially represented between ecological niches. In the last 10 years several methods have been pr…
View article: Correction: Host genetics and gut microbiota influence lipid metabolism and inflammation: potential implications for ALS pathophysiology in SOD1G93A mice
Correction: Host genetics and gut microbiota influence lipid metabolism and inflammation: potential implications for ALS pathophysiology in SOD1G93A mice Open
View article: Impact of Shifting Nitrogen to Phosphorus Limitation on Performance and Microbial Structure of a Polyhydroxyalkanoates Accumulating Population Selected with an Uncoupled Feeding
Impact of Shifting Nitrogen to Phosphorus Limitation on Performance and Microbial Structure of a Polyhydroxyalkanoates Accumulating Population Selected with an Uncoupled Feeding Open
View article: Human DNA hijacking microbiota surveys: causes and consequences in colon related 16s rRNA amplicon sequencing
Human DNA hijacking microbiota surveys: causes and consequences in colon related 16s rRNA amplicon sequencing Open
The efficiency of polymerase chain reaction (PCR) decreases under suboptimal conditions, such as low template concentration combined with high concentrations of similar sequences. Under these circumstances, mis-priming can occur, leading t…
View article: Evaluation of biomass conservation impact on wastewater-treating microbial communities using 16S rRNA gene sequencing
Evaluation of biomass conservation impact on wastewater-treating microbial communities using 16S rRNA gene sequencing Open
View article: Experimental tests challenge the evidence of a healthy human blood microbiome
Experimental tests challenge the evidence of a healthy human blood microbiome Open
The advent of next‐generation sequencing (NGS) technologies has made it possible to investigate microbial communities in various environments, including different sites within the human body. Therefore, the previously established belief of…
View article: Beneficial Effects of Micronutrient Supplementation in Restoring the Altered Microbiota and Gut–Retina Axis in Patients with Neovascular Age-Related Macular Degeneration—A Randomized Clinical Trial
Beneficial Effects of Micronutrient Supplementation in Restoring the Altered Microbiota and Gut–Retina Axis in Patients with Neovascular Age-Related Macular Degeneration—A Randomized Clinical Trial Open
Background/Objectives: Age-related macular degeneration (AMD) is a leading cause of visual impairment in the elderly and is characterized by a multifactorial etiology. Emerging evidence points to the potential involvement of the gut–retina…
View article: Host genetics and gut microbiota influence lipid metabolism and inflammation: potential implications for ALS pathophysiology in SOD1G93A mice
Host genetics and gut microbiota influence lipid metabolism and inflammation: potential implications for ALS pathophysiology in SOD1G93A mice Open
Amyotrophic Lateral Sclerosis (ALS) is a devastating neurodegenerative disorder characterized by the progressive loss of motor neurons, with genetic and environmental factors contributing to its complex pathogenesis. Dysregulated immune re…
View article: Gut microbiota in very early systemic sclerosis: the first case-control taxonomic and functional characterisation highlighting an altered butyric acid profile
Gut microbiota in very early systemic sclerosis: the first case-control taxonomic and functional characterisation highlighting an altered butyric acid profile Open
Objectives In systemic sclerosis (SSc), gastrointestinal involvement is one of the earliest events. We compared the gut microbiota (GM), its short-chain fatty acids (SCFAs) and host-derived free fatty acids (FFAs) in patients with very ear…
View article: Altered fatty acid metabolism rewires cholangiocarcinoma stemness features
Altered fatty acid metabolism rewires cholangiocarcinoma stemness features Open
View article: Verifying the feasibility of wastewater-based epidemiological monitoring for the small catchment and sewage networks with significant pretreatment
Verifying the feasibility of wastewater-based epidemiological monitoring for the small catchment and sewage networks with significant pretreatment Open
Wastewater-based epidemiology (WBE) has emerged as a valuable tool for COVID-19 monitoring, especially as the frequency of clinical testing diminishes. Beyond COronaVIrus Disease 19 (COVID-19), the tool's versatility extends to addressing …
View article: Evaluation of different molecular systems for detection and quantification of SARS-CoV-2 RNA from wastewater samples
Evaluation of different molecular systems for detection and quantification of SARS-CoV-2 RNA from wastewater samples Open
View article: Experimental colitis in young Tg2576 mice accelerates the onset of an Alzheimer’s-like clinical phenotype
Experimental colitis in young Tg2576 mice accelerates the onset of an Alzheimer’s-like clinical phenotype Open
Systemic inflammation and neuroinflammation affect the natural course of the sporadic form of Alzheimer’s disease (AD), as supported by epidemiological and preclinical data, and several epidemiological studies indicate a higher prevalence …
View article: Amyotrophic lateral sclerosis stratification: unveiling patterns with virome, inflammation, and metabolism molecules
Amyotrophic lateral sclerosis stratification: unveiling patterns with virome, inflammation, and metabolism molecules Open
View article: Oral microbiota signatures associated with viremia and CD4 recovery in treatment-naïve HIV-1-infected patients
Oral microbiota signatures associated with viremia and CD4 recovery in treatment-naïve HIV-1-infected patients Open
For the first time, we described an increase in the oral pro-inflammatory Proteobacteria phylum in INRs compared to IRs. We provided more evidence that saliva could be a non-invasive and less expensive approach for research involving the o…
View article: First Exploration of the Altered Microbial Gut–Lung Axis in the Pathogenesis of Human Refractory Chronic Cough
First Exploration of the Altered Microbial Gut–Lung Axis in the Pathogenesis of Human Refractory Chronic Cough Open
Purpose Cough represents a natural mechanism that plays an important defensive role in the respiratory tract, but in some conditions, it may become persistent, nonproductive, and harmful. In general, refractory chronic cough (RCC) occurs i…
View article: Alterations of circulating free fatty acids in patients with pemphigus vulgaris
Alterations of circulating free fatty acids in patients with pemphigus vulgaris Open
Free fatty acids (FFA) have gained research interest owing to their functions in both local and systemic immune regulation. Changes in the serum levels of anti‐inflammatory short chain fatty acids (SCFA), primarily derived from the gut mic…
View article: Experimental tests strongly challenge the evidence of a healthy human blood microbiome
Experimental tests strongly challenge the evidence of a healthy human blood microbiome Open
The advent of next-generation sequencing (NGS) technologies has made it doable to investigate the microbial communities in various environments, including all the different human body districts. Hence, the previously established belief of …
View article: Impact of Famine Length on the Structure and Performance of a PHA-Accumulating Community Under Uncoupled Feeding
Impact of Famine Length on the Structure and Performance of a PHA-Accumulating Community Under Uncoupled Feeding Open
View article: Differential Expression Analysis Utilizing Condition-Specific Metabolic Pathways
Differential Expression Analysis Utilizing Condition-Specific Metabolic Pathways Open
Pathway analysis is ubiquitous in biological data analysis due to the ability to integrate small simultaneous changes in functionally related components. While pathways are often defined based on either manual curation or network topologic…
View article: Targeting of tumor cells by custom antigen transfer: a novel approach for immunotherapy of cancer
Targeting of tumor cells by custom antigen transfer: a novel approach for immunotherapy of cancer Open
In the early stages of carcinogenesis, the transformed cells become “invisible” to the immune system. From this moment on, the evolution of the tumor depends essentially on the genotype of the primitive cancer cells and their subsequent ge…
View article: Immune landscape and oncobiota in HPV-Associated Colorectal Cancer: an explorative study
Immune landscape and oncobiota in HPV-Associated Colorectal Cancer: an explorative study Open
Worldwide more than 550,000 new patients suffering from malignant tumors are associated with human papillomaviruses (HPV) infection. However, only a small portion of patients infected progress to cancer, suggesting that other factors other…
View article: Intratumour microbiota modulates adrenocortical cancer responsiveness to mitotane
Intratumour microbiota modulates adrenocortical cancer responsiveness to mitotane Open
The infiltrating microbiota represents a novel cellular component of the solid tumour microenvironment that can influence tumour progression and response to therapy. Adrenocortical carcinoma (ACC) is a rare and aggressive endocrine maligna…
View article: Breast cancer: the first comparative evaluation of oncobiome composition between males and females
Breast cancer: the first comparative evaluation of oncobiome composition between males and females Open
View article: POS0613 THE ROLE OF MICROBIOTA IN DIFFERENT DISEASE STAGES OF SYSTEMIC SCLEROSIS: A POSSIBLE IMPACT IN GASTROINTESTINAL TRACT DISEASE ACTIVITY?
POS0613 THE ROLE OF MICROBIOTA IN DIFFERENT DISEASE STAGES OF SYSTEMIC SCLEROSIS: A POSSIBLE IMPACT IN GASTROINTESTINAL TRACT DISEASE ACTIVITY? Open
Background: Gastrointestinal tract (GIT) is affected in approximately 90% of systemic sclerosis (SSc) patients from the earliest disease stages. Microbiota has recently emerged as an important environmental factor in SSc pathogenesis. Obje…
View article: Corrigendum: Characterization of the “gut microbiota-immunity axis” and microbial lipid metabolites in atrophic and potential celiac disease
Corrigendum: Characterization of the “gut microbiota-immunity axis” and microbial lipid metabolites in atrophic and potential celiac disease Open
[This corrects the article DOI: 10.3389/fmicb.2022.886008.].