Maurizio Vecchi
YOU?
Author Swipe
View article: Sleep duration, selected circulating biomarkers, and colorectal cancer risk
Sleep duration, selected circulating biomarkers, and colorectal cancer risk Open
Sleep duration has been proposed to influence the risk of colorectal cancer (CRC). An involvement of inflammation, metabolic disorders, and gut permeability has been suggested. We investigated the relationship between sleep duration and CR…
View article: Long versus conventional peripheral intravenous catheters to reduce venipunctures during hospital stay: A randomized controlled trial
Long versus conventional peripheral intravenous catheters to reduce venipunctures during hospital stay: A randomized controlled trial Open
Background: Selecting the most appropriate vascular access is crucial to minimizing catheter-related complications and repeated-venipunctures. The objective of this study is to evaluate whether the use of a long peripheral catheter (LPC), …
View article: The Ten Dietary Commandments for Patients with Irritable Bowel Syndrome: A Narrative Review with Pragmatic Indications
The Ten Dietary Commandments for Patients with Irritable Bowel Syndrome: A Narrative Review with Pragmatic Indications Open
Irritable bowel syndrome (IBS) is a gut–brain axis chronic disorder, characterized by recurrent abdominal pain and altered bowel habits in the absence of organic pathology. Nutrition plays a central role in symptom management, yet no singl…
View article: A "movement" worth making: why and how Transfusion Services can play a role in Fecal Microbiota Transplant programs.
A "movement" worth making: why and how Transfusion Services can play a role in Fecal Microbiota Transplant programs. Open
Fecal Microbiota Transplantation (FMT) is an innovative therapy with growing applications, particularly for recurrent Clostridioides difficile infections (rCDI). However, the broader use of FMT is challenged by the complexities of donor re…
View article: Fidaxomicin for <i>Clostridioides difficile</i> infection in patients with inflammatory bowel disease: a multicenter retrospective cohort study
Fidaxomicin for <i>Clostridioides difficile</i> infection in patients with inflammatory bowel disease: a multicenter retrospective cohort study Open
Background and aims Inflammatory bowel disease (IBD) patients with Clostridioides difficile infection (CDI) are at increased risk of adverse outcomes. Data on fidaxomicin use in IBD remain scarce. We assessed the effectiveness and safety o…
View article: Is IBS a Food Allergy? Confocal Laser Endomicroscopy Findings in Patients with IBS: A Narrative Review
Is IBS a Food Allergy? Confocal Laser Endomicroscopy Findings in Patients with IBS: A Narrative Review Open
Irritable bowel syndrome (IBS) is a gut–brain interaction disorder often associated with food-related triggers, yet the efficacy of common exclusion diets remains debated. Confocal laser endomicroscopy (CLE) offers real-time, high-resoluti…
View article: Effect of antithrombotic therapies on small bowel bleeding: an European multicenter retrospective study
Effect of antithrombotic therapies on small bowel bleeding: an European multicenter retrospective study Open
Background/Aims: Small bowel bleeding (SBB) is the main indication for videocapsule endoscopy (VCE); the diagnostic yield (DY) could be influenced by antithrombotic therapies. We explored the effects of these therapies on SBB.Methods: Cons…
View article: Estrogen-related differences in antitumor immunity and gut microbiome contribute to sexual dimorphism of colorectal cancer
Estrogen-related differences in antitumor immunity and gut microbiome contribute to sexual dimorphism of colorectal cancer Open
Colorectal cancer (CRC) is a multifaceted disease whose development and progression varies depending on tumor location, age of patients, infiltration of immune cells within cancer lesions, and the tumor microenvironment. These pathophysiol…
View article: <i>Porphyromonas gingivalis</i> fuels colorectal cancer through CHI3L1-mediated iNKT cell-driven immune evasion
<i>Porphyromonas gingivalis</i> fuels colorectal cancer through CHI3L1-mediated iNKT cell-driven immune evasion Open
The interaction between the gut microbiota and invariant Natural Killer T (iNKT) cells plays a pivotal role in colorectal cancer (CRC). The pathobiont Fusobacterium nucleatum influences the anti-tumor functions of CRC-infiltrating iNKT cel…
View article: Ultrasound peer-to-peer courses for medical students: a cross-sectional study of satisfaction and efficacy
Ultrasound peer-to-peer courses for medical students: a cross-sectional study of satisfaction and efficacy Open
Background Point-of-care ultrasound (POCUS) is ideal for providing rapid answers to many clinical problems. It is therefore important that instruction on ultrasound (US) basics be provided as part of university education. The aim of this s…
View article: Pan-enteric Capsule Endoscopy to Characterize Crohn’s Disease Phenotypes and Predict Clinical Outcomes in Children and Adults: The Bomiro Study
Pan-enteric Capsule Endoscopy to Characterize Crohn’s Disease Phenotypes and Predict Clinical Outcomes in Children and Adults: The Bomiro Study Open
Background Pan-enteric capsule endoscopy (PCE) provides useful information for the management of Crohn’s disease (CD), especially in children. No study has evaluated the ability of PCE to characterize CD phenotypes and outcomes in children…
View article: Estrogen-related differences in antitumor immunity and the gut microbiome contribute to sexual dimorphism of colorectal cancer
Estrogen-related differences in antitumor immunity and the gut microbiome contribute to sexual dimorphism of colorectal cancer Open
Colorectal cancer (CRC) is a multifaceted disease whose development and progression varies depending on tumor location, age of patients, infiltration of immune cells within cancer lesions, and the tumor microenvironment. These pathophysiol…
View article: P248 Feasibility, accuracy and reproducibility of the ultrasound measurement of psoas muscle compared to bioelectrical impedance analysis for the evaluation of skeletal muscle mass in patients with IBD
P248 Feasibility, accuracy and reproducibility of the ultrasound measurement of psoas muscle compared to bioelectrical impedance analysis for the evaluation of skeletal muscle mass in patients with IBD Open
Background Sarcopenia is characterized by the loss of muscle mass and it is a strong predictor of disability and poor outcomes in several chronic gastrointestinal diseases such as inflammatory bowel diseases (IBD). Therefore, it is useful …
View article: P981 Risankizumab, but not ustekinumab or vedolizumab, downregulates IL-23-induced mucosal pathogenic Th17 cells in patients with Crohn’s disease
P981 Risankizumab, but not ustekinumab or vedolizumab, downregulates IL-23-induced mucosal pathogenic Th17 cells in patients with Crohn’s disease Open
Background We recently described an interleukin(IL)-23-inducible pathogenic subset of CCR6+CXCR3-CCR5+ mucosal T helper (Th)17 cells (pTh17) infiltrating Crohn’s disease (CD) inflamed mucosa and specifically activated in response to Adhere…
View article: P1237 Development of an algorithm to identify the best donor-recipient match for FMT in IBD patients based on immune system/microbiota interactions
P1237 Development of an algorithm to identify the best donor-recipient match for FMT in IBD patients based on immune system/microbiota interactions Open
Background IBD are characterized by uncontrolled immune responses, in genetically predisposed individuals, to the dysbiotic microbiota. Its modulation has thus emerged as a potential therapeutic strategy . Fecal microbiota transplantation …
View article: P504 Prevalence of gastrointestinal infections in ulcerative colitis patients assessed with QIASTAT-DX® GASTROINTESTINAL PANEL 2
P504 Prevalence of gastrointestinal infections in ulcerative colitis patients assessed with QIASTAT-DX® GASTROINTESTINAL PANEL 2 Open
Background In inflammatory bowel disease (IBD), an acute clinical flare may be due to either disease exacerbation or an enteric infection. Thus, it is recommended to exclude infections before escalating IBD therapy. In this setting, conven…
View article: P200 Oral Mannitol for bowel preparation in IBD patients: a post-hoc analysis of a multicentre, controlled, randomized clinical trial
P200 Oral Mannitol for bowel preparation in IBD patients: a post-hoc analysis of a multicentre, controlled, randomized clinical trial Open
Background Bowel preparation is the most burdensome part of the whole colonoscopy procedure according to patients. A diagnosis of Inflammatory Bowel Disease (IBD) implies the need for lifelong repeated colonoscopies, therefore amplifying t…
View article: P908 Real-life effectiveness and safety of tofacitinib and vedolizumab as a second-line therapy in anti-TNFs experienced patients ulcerative colitis: preliminary results of an IGIBD study (VE2TO-UC)
P908 Real-life effectiveness and safety of tofacitinib and vedolizumab as a second-line therapy in anti-TNFs experienced patients ulcerative colitis: preliminary results of an IGIBD study (VE2TO-UC) Open
Background Drug positioning in ulcerative colitis (UC) patients refractory to anti-tumor necrosis factor (TNF) is still debated. We aimed to compare the real-life effectiveness and safety of tofacitinib and vedolizumab as second-line thera…
View article: P1105 Short-term exposure to environmental air pollution and inflammatory bowel disease flares: a time-stratified case cross-over study
P1105 Short-term exposure to environmental air pollution and inflammatory bowel disease flares: a time-stratified case cross-over study Open
Background Some epidemiological studies suggest that long-term exposure to environmental air pollutants, such as particulate matter (PM), could have a role in inflammatory bowel disease (IBD) incidence and pathogenesis. However, less is kn…
View article: P921 Maintenance of clinical, biochemical and transmural remission in inflammatory bowel disease patients switching from intravenous to subcutaneous infliximab
P921 Maintenance of clinical, biochemical and transmural remission in inflammatory bowel disease patients switching from intravenous to subcutaneous infliximab Open
Background Subcutaneous (SC) infliximab (IFX) effectively maintains biochemical, clinical and endoscopic remission in inflammatory bowel disease (IBD) with a comparable safety profile to intravenous (IV) formulation. Transmural healing is …
View article: Porphyromonas gingivalis fuels colorectal cancer through CHI3L1-mediated iNKT cell-driven immune evasion
Porphyromonas gingivalis fuels colorectal cancer through CHI3L1-mediated iNKT cell-driven immune evasion Open
The interaction between the gut microbiota and invariant Natural Killer T (iNKT) cells plays a pivotal role in colorectal cancer (CRC). Porphyromonas gingivalis is a keystone oral pathogen associated with CRC. The oral pathobiont Fusobacte…