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View article: CNSC-29. INVESTIGATING THE INFLUENCE OF DOPAMINERGIC ACTIVITY ON THE GLIOBLASTOMA NICHE
CNSC-29. INVESTIGATING THE INFLUENCE OF DOPAMINERGIC ACTIVITY ON THE GLIOBLASTOMA NICHE Open
Glioblastoma (GBM) is an incurable disease of adults and children and the deadliest form of central nervous system (CNS) malignancy. Despite major advances in our understanding of GBM biology in recent years, the prognosis for patients who…
View article: Overview of The Canadian Clinician Investigator Trainees’ Research Presented at The 2020 CSCI-CITAC Joint Meeting
Overview of The Canadian Clinician Investigator Trainees’ Research Presented at The 2020 CSCI-CITAC Joint Meeting Open
The 2020 Annual General Meeting (AGM) and Young Investigators’ Forum of the Canadian Society for Clinical Investigation / Société Canadienne de Recherches Clinique (CSCI/SCRC) and Clinician Investigator Trainee Association of Canada/Associ…
View article: Overview of the Canadian Clinician Investigator Trainees’ research presented at the 2019 CSCI-CITAC Joint Meeting
Overview of the Canadian Clinician Investigator Trainees’ research presented at the 2019 CSCI-CITAC Joint Meeting Open
The 2019 Annual General Meeting and Young Investigators’ Forum of the Canadian Society for Clinical Investigation / Société Canadienne de Recherche Clinique (CSCI/SCRC) and Clinician Investigator Trainee Association of Canada / Association…
View article: Beyond Conventional Models: Recreating the Initiation, Evolution, and Genome of GBM
Beyond Conventional Models: Recreating the Initiation, Evolution, and Genome of GBM Open
Background Imagining ways to prevent or treat glioblastoma (GBM) have been hindered by a lack of understanding of its pathogenesis. Although PDGF-AA overexpression may be an early event, critical details of the core biology are lacking. Ex…
View article: TMOD-02. A MODEL OF THE INITIATION AND GENOMIC LANDSCAPE OF GLIOBLASTOMA (GBM)
TMOD-02. A MODEL OF THE INITIATION AND GENOMIC LANDSCAPE OF GLIOBLASTOMA (GBM) Open
IDH-wildtype GBM is the most common variant of this cancer and occurs in older adults. Unfortunately patients’ tumors are either inherently resistant to standard treatment, which includes radio- and chemo-therapy, or acquire resistance dur…
View article: CSIG-19. RECEPTOR TYROSINE KINASE PHOSPHORYLATION IN A MODEL SYSTEM OF GBM
CSIG-19. RECEPTOR TYROSINE KINASE PHOSPHORYLATION IN A MODEL SYSTEM OF GBM Open
Glioblastoma Multiforme (GBM) is the most common brain tumour in adults, and despite our best treatments is fatal. Multiple receptor tyrosine kinases (RTKs) are amplified in GBM: 45% have elevated expression of Epidermal Growth Factor Rece…