Explanipedia

Assessment of Online Adaptive MRI-Guided Stereotactic Body Radiotherapy (SBRT) With an Integrated Boost to the Dominant Lesion in Prostate Cancer Open

Kyle R. Padgett, Jonathan Cabrera, Levent Şensoy, William Jin, Matthew C. Abramowitz , et al. · 2025

Purpose/objective Online adaptive radiotherapy (ART) with daily MR imaging can improve dosimetric accuracy by accounting for anatomical changes throughout the course of treatment. Existing daily ART prostate studies have diverse conclusion…

Defining occult disease in glioblastoma using spectroscopic MRI: implications for clinical target volume delineation Open

Jonathan B. Bell, Sulaiman Sheriff, Mohammed Goryawala, Kaylie Cullison, Gregory Azzam , et al. · 2025

Outcomes of Radium-223 and Stereotactic Ablative Radiotherapy Versus Stereotactic Ablative Radiotherapy for Oligometastatic Prostate Cancers: The RAVENS Phase II Randomized Trial Open

Jarey H. Wang, Alexander D. Sherry, Soha Bazyar, Philip Sutera, Noura Radwan , et al. · 2025

PURPOSE Randomized clinical trials (RCTs) have shown progression-free survival (PFS) benefits of metastasis-directed therapy (MDT) without androgen deprivation therapy for oligometastatic castration-sensitive prostate cancer (omCSPC). Most…

Correlation of T2-Weighted Magnetic Resonance Imaging (MRI), Computed Tomography (CT), and Cone Beam Computed Tomography (CBCT) Radiomic Features for Prostate Cancer Open

Rodrigo Delgadillo, Benjamin Spieler, John C. Ford, Fei Yang, Matthew T. Studenski , et al. · 2025

Repeatability, reproducibility, and the effects of radiotherapy on radiomic features of lowfield MR-LINAC images of the prostate Open

Penny R. Anderson, Nesrin Dogan, John C. Ford, Kyle R. Padgett, Garrett Simpson , et al. · 2025

Definitive radiotherapy (RT) has been shown to be a successful method of treating prostate cancer (PCa) patients. Through radiomics, a quantitative analysis of medical images, it is possible to adapt treatment early on, which may prevent o…

Integrated framework for quantitative T2-weighted MRI analysis following prostate cancer radiotherapy Open

Evangelia I. Zacharaki, Adrian Breto, Ahmad Algohary, Veronica Wallaengen, Sandra M. Gaston , et al. · 2024

The developed methodology allows to automate longitudinal analysis reducing data acquisition-related variation and improving consistency. The quantitative characterization of RT-induced changes in T2w will lead to new understanding of radi…

Increasing the efficiency of cone-beam CT based delta-radiomics using automated contours to predict radiotherapy-related toxicities in prostate cancer Open

Rodrigo Delgadillo, Anthony M Deana, John C. Ford, Matthew T. Studenski, Kyle R. Padgett , et al. · 2024

A Smart Water Bottle and Companion App (HidrateSpark 3) to Improve Bladder-Filling Compliance in Patients With Prostate Cancer Receiving Radiotherapy: Nonrandomized Trial of Feasibility and Acceptability Open

William Jin, Christopher Montoya, Benjamin Rich, Crystal Seldon, Miguel Noy , et al. · 2024

Background Patients with prostate cancer undergoing radiation therapy (RT) need comfortably full bladders to reduce toxicities during treatment. Poor compliance is common with standard of care written or verbal instructions, leading to was…

Uncovering prostate cancer aggressiveness signal in T2‐weighted MRI through a three‐reference tissues normalization technique Open

Ahmad Algohary, Evangelia I. Zacharaki, Adrian Breto, Mohammad Alhusseini, Veronica Wallaengen , et al. · 2023

Quantitative T2‐weighted MRI (T2W) interpretation is impeded by the variability of acquisition‐related features, such as field strength, coil type, signal amplification, and pulse sequence parameters. The main purpose of this work is to de…

Clinical-Genomic Risk Group Classification of Suspicious Lesions on Prostate Multiparametric-MRI Open

Radka Stoyanova, Olmo Zavala‐Romero, Deukwoo Kwon, Adrian Breto, Isaac Xu , et al. · 2023

The utilization of multi-parametric MRI (mpMRI) in clinical decisions regarding prostate cancer patients’ management has recently increased. After biopsy, clinicians can assess risk using National Comprehensive Cancer Network (NCCN) risk s…

Patterns of Recurrence Following Radiation and ADT for Pathologic Lymph Node Positive Prostate Cancer: A Multi-Institutional Study Open

Leslie K. Ballas, C.A. Reddy, Hye Ri Han, Jasbir S. Makar, Omar Y. Mian , et al. · 2023

A Smart Water Bottle and Companion App (HidrateSpark 3) to Improve Bladder-Filling Compliance in Patients With Prostate Cancer Receiving Radiotherapy: Nonrandomized Trial of Feasibility and Acceptability (Preprint) Open

William Jin, Christopher Montoya, Benjamin Rich, Crystal Seldon, Miguel Noy , et al. · 2023

BACKGROUND Patients with prostate cancer undergoing radiation therapy (RT) need comfortably full bladders to reduce toxicities during treatment. Poor compliance is common with standard of care written or verbal instructions, leading to wa…

ED visits, hospital admissions and treatment breaks in head/neck cancer patients undergoing radiotherapy Open

Shareen Patel, Benjamin Rich, Leif‐Erik D. Schumacher, Zoukaa Sargi, Melissa Masforroll , et al. · 2023

Objectives Radiation therapy (RT) is an integral part of treatment of head/neck cancer (HNC) but is associated with many toxicities. We sought to evaluate sociodemographic, pathologic, and clinical factors associated with emergency departm…

Delineation of recurrent glioblastoma by whole brain spectroscopic magnetic resonance imaging Open

Jonathan B. Bell, William Jin, Mohammed Goryawala, Gregory Azzam, Matthew C. Abramowitz , et al. · 2023

Background Glioblastoma (GBM) cellularity correlates with whole brain spectroscopic MRI (sMRI) generated relative choline to N -Acetyl-Aspartate ratio (rChoNAA) mapping. In recurrent GBM (rGBM), tumor volume (TV) delineation is challenging…

Integrated Framework for Quantitative T2-Weighted MRI Analysis Following Prostate Cancer Radiotherapy Open

Evangelia I. Zacharaki, Adrian Breto, Ahmad Algohary, Veronica Wallaengen, Sandra M. Gaston , et al. · 2023

Cone-beam CT delta-radiomics to predict genitourinary toxicities and international prostate symptom of prostate cancer patients: a pilot study Open

Rodrigo Delgadillo, Benjamin Spieler, Anthony M Deana, John C. Ford, Deukwoo Kwon , et al. · 2022

Addressing Challenges and Controversies in the Management of Prostate Cancer with Multidisciplinary Teams Open

Neal D. Shore, Alicia K. Morgans, Ghassan El‐Haddad, Sandy Srinivas, Matthew C. Abramowitz · 2022

Longitudinal Changes and Predictive Value of Multiparametric MRI Features for Prostate Cancer Patients Treated with MRI-Guided Lattice Extreme Ablative Dose (LEAD) Boost Radiotherapy Open

Ahmad Algohary, Mohammad Alhusseini, Adrian Breto, Deukwoo Kwon, Isaac Xu , et al. · 2022

We investigated the longitudinal changes in multiparametric MRI (mpMRI) (T2-weighted, Apparent Diffusion Coefficient (ADC), and Dynamic Contrast Enhanced (DCE-)MRI) of prostate cancer patients receiving Lattice Extreme Ablative Dose (LEAD)…

Assessment of CT to CBCT contour mapping for radiomic feature analysis in prostate cancer Open

Ryder M. Schmidt, Rodrigo Delgadillo, John C. Ford, Kyle R. Padgett, Matthew T. Studenski , et al. · 2021

This study provides a quantitative assessment of the accuracy of a commercially available deformable image registration (DIR) algorithm to automatically generate prostate contours and additionally investigates the robustness of radiomic fe…

Levels of Evidence for Radiation Therapy Recommendations in the National Comprehensive Cancer Network (NCCN) Clinical Guidelines Open

Miguel Noy, Benjamin Rich, Ricardo Llorente, Deukwoo Kwon, Matthew C. Abramowitz , et al. · 2021

Only 9.7% of radiation therapy recommendations in NCCN guidelines are category I CE. The highest levels of evidence for radiation therapy are in breast and cervical cancers. Despite major advances in the field, these data underline that th…

Cone Beam CT Based Delta-Radiomics of Prostate Cancer Patients and Their Correlation to Quality of Life, Genitourinary and Gastrointestinal Toxicities Open

Rodrigo Delgadillo, Benjamin Spieler, A. Deana, John C. Ford, D. Kwon , et al. · 2021

Quantification of Target Volume Changes on Radiation Planning MRI in IDH-Wildtype Glioblastoma Open

Jonathan B. Bell, Benjamin Rich, I Mihaylov, Carolina Benjamin, Eric A. Mellon , et al. · 2021

Heterogeneity in Genomic Risk Assessment from Tissue Based Prognostic Signatures Used in the Biopsy Setting and the Impact of Magnetic Resonance Imaging Targeted Biopsy Open

Sanoj Punnen, Radka Stoyanova, Deukwoo Kwon, Isildinha M. Reis, Nachiketh Soodana‐Prakash , et al. · 2020

There is variation in genomic risk assessment from different biopsy cores regardless of the signature used. Magnetic resonance imaging directed biopsy or profiling the highest grade core resulted in the highest genomic risk level in most c…

Post-Treatment Biopsy Positivity In Prostate Cancer Patients Undergoing MpMRI-Targeted Radiation Dose Escalation Open

Jessica Meshman, Benjamin Farnia, Radka Stoyanova, Alan Dal Pra, Matthew C. Abramowitz , et al. · 2020

The role of radiomics in prostate cancer radiotherapy Open

Rodrigo Delgadillo, John C. Ford, Matthew C. Abramowitz, Alan Dal Pra, Alan Pollack , et al. · 2020

Segmentation of prostate and prostate zones using deep learning Open

Olmo Zavala‐Romero, Adrian Breto, Isaac Xu, Yu-Cherng Chang, Nicole Gautney , et al. · 2020

Phase I Trial of MRI-Guided Prostate Cancer Lattice Extreme Ablative Dose (LEAD) Boost Radiation Therapy Open

Alan Pollack, Felix M. Chinea, Elizabeth Bossart, Deukwoo Kwon, Matthew C. Abramowitz , et al. · 2020

Contrasting Circulating Tumor Cells and Free Circulating DNA Responses in Men Treated for Prostate Cancer after Primary Versus Salvage Radiotherapy Open

Radka Stoyanova, Adrian Breto, Adrian Ishkanian, Alan Dal Pra, Alan Pollack , et al. · 2020

Purpose: To investigate the relationships between circulating tumor cells (CTCs), free circulating DNA (fcDNA) and biochemical response in prostate cancer patients treated primarily versus salvage radiotherapy (RT). Methods and Materials: …

Long‐term opioid use in curative‐intent radiotherapy: One‐Year outcomes in head/neck cancer patients Open

Leif‐Erik D. Schumacher, Zoukaa Sargi, Melissa Masforroll, Deukwoo Kwon, Wei Zhao , et al. · 2019

Background No study has determined the incidence of long‐term opioid use, or risk factors for long‐term use, ≥1 year after radiotherapy. Methods Medical records of 276 head/neck cancer patients were retrospectively assessed for persistent …

Clinical-genomic Risk Group Classification of Suspicions Lesions on Prostate mpMRI Open

Olmo Zavala‐Romero, Alan Pollack, Deukwoo Kwon, Adrian Breto, Elai Davicioni , et al. · 2019

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