Matthew Cawson
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View article: The Economic and Clinical Impact of Recurring Automated Red Blood Cell Exchange to Manage Sickle Cell Disease in the UK
The Economic and Clinical Impact of Recurring Automated Red Blood Cell Exchange to Manage Sickle Cell Disease in the UK Open
aRBCX shows potential to improve health outcomes and reduce healthcare costs for individuals with SCD initiating a chronic DMT programme.
View article: Trends in cell collection and apheresis practices: Insights from a cross-sectional study on the use of Spectra Optia in collection and transplant centers
Trends in cell collection and apheresis practices: Insights from a cross-sectional study on the use of Spectra Optia in collection and transplant centers Open
This study highlights the breadth of indications for which Spectra Optia is used, and the dynamic nature and growth prospects of the field. Innovation and standardization in apheresis technologies will be important to drive the potential o…
View article: Cost-Effectiveness of a Digital Leakage Notification System (Heylo™) for People with Ileostomies or Colostomies in the United Kingdom
Cost-Effectiveness of a Digital Leakage Notification System (Heylo™) for People with Ileostomies or Colostomies in the United Kingdom Open
View article: Cost-effectiveness analysis of HIV pre-exposure prophylaxis in Japan
Cost-effectiveness analysis of HIV pre-exposure prophylaxis in Japan Open
While global efforts have been made to prevent transmission of HIV, the epidemic persists. Men who have sex with men (MSM) are at high risk of infection. Despite evidence of its cost-effectiveness in other jurisdictions, pre-exposure proph…
View article: Time trade-off study to establish utility decrements in individuals with a spinal cord injury who perform intermittent catheterization
Time trade-off study to establish utility decrements in individuals with a spinal cord injury who perform intermittent catheterization Open
Worry associated with hospitalization had the greatest impact on patients' health-related quality of life (HRQoL). The catheterization process, such as the lubrication and repositioning of the catheter, also impacted on patients' HRQoL.
View article: Exploring the impact of excessive daytime sleepiness caused by obstructive sleep apnea on patient and partner quality of life: a time trade-off utility study in the UK general public
Exploring the impact of excessive daytime sleepiness caused by obstructive sleep apnea on patient and partner quality of life: a time trade-off utility study in the UK general public Open
View article: Survival analyses from the <scp>CENTAUR</scp> trial in amyotrophic lateral sclerosis: Evaluating the impact of treatment crossover on outcomes
Survival analyses from the <span>CENTAUR</span> trial in amyotrophic lateral sclerosis: Evaluating the impact of treatment crossover on outcomes Open
Introduction/Aims Trials incorporating placebo‐to‐active treatment crossover are encouraged in fatal conditions like amyotrophic lateral sclerosis (ALS) but may underestimate active treatment survival benefit. Here, we apply methods for mo…
View article: Examining patient and professional perspectives in the UK for gene therapy in haemophilia
Examining patient and professional perspectives in the UK for gene therapy in haemophilia Open
Introduction With the development of gene therapy for people with haemophilia (PWH), it is important to understand how people impacted by haemophilia (PIH) and clinicians prioritise haemophilia treatment attributes to support informed trea…
View article: S7 Estimating the potential impact of residual EDS on the QoL of patients with OSA and, for the first time, their partners, using a time trade-off methodology
S7 Estimating the potential impact of residual EDS on the QoL of patients with OSA and, for the first time, their partners, using a time trade-off methodology Open
Introduction and Objectives Excessive daytime sleepiness (EDS) is a common symptom of obstructive sleep apnoea (OSA), persisting in 9% to 22% of patients despite primary airway therapy (residual EDS). EDS can impair work productivity and d…
View article: Patient preferences and priorities for haemophilia gene therapy in the US: A discrete choice experiment
Patient preferences and priorities for haemophilia gene therapy in the US: A discrete choice experiment Open
IntroductionGene therapy has shown promise in clinical trials for patients with haemophilia, but patient preference studies have focused on factor replacement treatments.AimWe conducted a discrete choice experiment (DCE) to investigate the…
View article: Patient preferences and priorities for haemophilia gene therapy in the US: A discrete choice experiment
Patient preferences and priorities for haemophilia gene therapy in the US: A discrete choice experiment Open
Introduction Gene therapy has shown promise in clinical trials for patients with haemophilia, but patient preference studies have focused on factor replacement treatments. Aim We conducted a discrete choice experiment (DCE) to investigate …
View article: Budget Impact Analysis of Gemtuzumab Ozogamicin for the Treatment of CD33-Positive Acute Myeloid Leukemia
Budget Impact Analysis of Gemtuzumab Ozogamicin for the Treatment of CD33-Positive Acute Myeloid Leukemia Open
View article: PIN14 HEALTH UTILITY ESTIMATES FOR CONGENITAL CYTOMEGALOVIRUS DISEASE: CONCEPTUAL DESIGN CONSIDERATIONS
PIN14 HEALTH UTILITY ESTIMATES FOR CONGENITAL CYTOMEGALOVIRUS DISEASE: CONCEPTUAL DESIGN CONSIDERATIONS Open
View article: Patients with unilateral transfemoral amputation treated with a percutaneous osseointegrated prosthesis
Patients with unilateral transfemoral amputation treated with a percutaneous osseointegrated prosthesis Open
Aims The aim of this study was to compare the cost-effectiveness of treatment with an osseointegrated percutaneous (OI-) prosthesis and a socket-suspended (S-) prosthesis for patients with a transfemoral amputation. Patients and Methods A …