Matthew Chu
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Advancing Clinical Trial Methodology and Reporting of Outcomes for Exclusive Enteral Nutrition and Partial Enteral Nutrition in Crohn's Disease: Challenges and Recommendations Open
Background Exclusive enteral nutrition (EEN) is an efficacious therapy for active Crohn's disease (CD), particularly in the paediatric setting. Aim This review critically evaluates key elements of interventional EEN trials in paediatric an…
Frequent Dietetic Involvement Enhances Adherence and Clinical Outcomes of Exclusive Enteral Nutrition in Adults With Crohn's Disease Open
Background and Aim Use of Exclusive Enteral Nutrition (EEN) in adults has been limited by lack of defined protocols, poor adherence and perceived lack of efficacy. This study evaluated EEN therapy in adults with Crohn's disease (CD) to ide…
Meta‐Analysis: Exclusive Enteral Nutrition in Adults With Ulcerative Colitis Open
Background Exclusive enteral nutrition (EEN) is an established dietary therapy for Crohn's disease but its role in ulcerative colitis remains unclear. Aims To investigate the efficacy of EEN in adults with active ulcerative colitis and com…
View article: P0735 Early dietetic assessment predicts clinical efficacy of Exclusive Enteral Nutrition in adults with Crohn’s disease
P0735 Early dietetic assessment predicts clinical efficacy of Exclusive Enteral Nutrition in adults with Crohn’s disease Open
Background Exclusive Enteral Nutrition (EEN) is an effective but underutilised therapy in adults with Crohn’s disease (CD). Key factors influencing patient adherence and clinical outcomes for EEN in adults remain poorly understood. This st…
View article: P0690 Purposeful design and integration of a pilot Inflammatory Bowel Disease (IBD) diet clinic into a multi-disciplinary IBD service demonstrates exemplar service utility and is of high value to patients
P0690 Purposeful design and integration of a pilot Inflammatory Bowel Disease (IBD) diet clinic into a multi-disciplinary IBD service demonstrates exemplar service utility and is of high value to patients Open
Background International guidelines recommend people with inflammatory bowel disease (IBD) have access to a dietitian who can undertake a comprehensive nutrition assessment and provide personalised dietary counselling. Few Australian terti…
View article: Context-Dependent Heterotypic Assemblies of Inherently Disordered Peptides
Context-Dependent Heterotypic Assemblies of Inherently Disordered Peptides Open
Despite being ubiquitous within proteins and playing a crucial role in context-dependent interactions for protein functions, intrinsically disorder regions (IDRs), unlike structured motifs, are often overlooked for designing peptide assemb…
Editorial: Sonographic assessment of colonic content—A new tool for constipation? Authors' reply Open
LINKED CONTENT This article is linked to Mathias et al papers. To view these articles, visit https://doi.org/10.1111/apt.18029 and https://doi.org/10.1111/apt.18100
Meta‐analysis: Intestinal ultrasound to evaluate colonic contents and constipation Open
Summary Background Constipation can be diagnosed clinically using the Rome criteria. Ultrasound (US), which lacks the radiation exposure of conventional X‐ray, holds promise as a non‐invasive tool to evaluate colonic contents and constipat…
Association of Circulating Plasma Secreted Frizzled-Related Protein 5 (Sfrp5) Levels with Cardiac Function Open
Secreted frizzled-related protein 5 (SFRP5) is a novel anti-inflammatory adipokine that may play a role in cardiovascular development and disease. However, there is yet to be a comprehensive investigation into whether circulating SFRP5 can…
View article: Comparing the resource implications of old and new colorectal adenoma surveillance guidelines in Australia
Comparing the resource implications of old and new colorectal adenoma surveillance guidelines in Australia Open
Background The latest update to the Australian adenoma surveillance guideline in 2018 introduced a novel risk stratification system with updated surveillance recommendations. The resource implications of adopting this new system are unclea…
Potentially avoidable mortality after endoscopic retrograde cholangiopancreatography in Australia: an 8‐year qualitative analysis Open
Background Endoscopic retrograde cholangiopancreatography (ERCP) is a commonly performed procedure worldwide. The aim of this study was to examine cases of mortality after ERCP to identify clinical incidents that are potentially preventabl…
P499 Exclusive enteral nutrition induces transmural healing in adults with active Crohn’s disease Open
Background Exclusive enteral nutrition (EEN) is a nutrition-based therapy for active Crohn’s Disease (CD). Transmural healing is a novel therapeutic paradigm in CD, holding benefit beyond endoscopic mucosal healing. There are limited data …
View article: Quality of colonoscopy performed by medical or surgical specialists and trainees in five Australian hospitals
Quality of colonoscopy performed by medical or surgical specialists and trainees in five Australian hospitals Open
Significant differences in the quality of colonoscopy in Australia exist, even when national benchmarks are achieved. The role of possible contributing factors, like procedural specialty and patient gender need further evaluation.
Heart failure is associated with low circulating levels of secreted frizzled receptor protein 5 (Sfrp5) Open
Background/Introduction Obesity and metabolic dysregulation are closely associated with the pathophysiology of multiple cardiovascular diseases (CVD). To date, the pathophysiological mechanism(s) of obesity and its link with cardiovascular…