Matthew D. Egberg
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View article: Trends in Surgical Recurrence Among Pediatric Crohn’s Disease Patients Using Administrative Claims Data
Trends in Surgical Recurrence Among Pediatric Crohn’s Disease Patients Using Administrative Claims Data Open
Background Despite the growing armamentarium of medical therapies for Crohn’s disease (CD), well over half of patients with CD will require surgical intervention. We estimated the surgical recurrence risk and characterized postoperative tr…
View article: Low Risk of Lymphoma in Pediatric Patients Treated for Inflammatory Bowel Disease
Low Risk of Lymphoma in Pediatric Patients Treated for Inflammatory Bowel Disease Open
INTRODUCTION: Despite the effectiveness of immune-suppressing therapies in treating pediatric inflammatory bowel diseases (IBDs), concerns of lymphoma may limit their use. We used a large administrative claims database to evaluate the risk…
View article: Higher Mortality Rates Associated with Clostridioides difficile Infection in Hospitalized Children with Cystic Fibrosis
Higher Mortality Rates Associated with Clostridioides difficile Infection in Hospitalized Children with Cystic Fibrosis Open
Objective(s): To determine the impact of Clostridioides difficile Infection (CDI) among pediatric Cystic Fibrosis (CF) hospitalizations using a large nationally representative pediatric hospital database . Study design: We identified Cysti…
View article: EFFECTIVENESS OF ANTI-TNF THERAPY COMPARED TO IMMUNE MODULATOR FOR PREVENTION OF SURGICAL RECURRENCE IN PEDIATRIC CD
EFFECTIVENESS OF ANTI-TNF THERAPY COMPARED TO IMMUNE MODULATOR FOR PREVENTION OF SURGICAL RECURRENCE IN PEDIATRIC CD Open
BACKGROUND Crohn’s disease (CD) is an immune-mediated, chronic inflammatory disease without a present cure. Surgical intervention for disease complications is common among CD patients, however post-operative strategies to prevent disease r…
View article: The Cumulative Incidence of Pouchitis in Pediatric Patients With Ulcerative Colitis
The Cumulative Incidence of Pouchitis in Pediatric Patients With Ulcerative Colitis Open
Background Despite highly effective therapies, many children develop medically refractory ulcerative colitis (UC) and undergo proctocolectomy with ileal pouch–anal anastomosis (IPAA). We sought to determine the incidence, risk, and burden …
View article: Obesity Increases the Risk of Hospital Readmission Following Intestinal Surgery for Children With Crohn Disease
Obesity Increases the Risk of Hospital Readmission Following Intestinal Surgery for Children With Crohn Disease Open
Objectives: Obese habitus can lead to adverse outcomes for colorectal surgeries due to technical challenges and pro‐inflammatory immune mediators associated with excess adipose tissue. Surgical planning, pre‐operative risk stratification, …
View article: THE CUMULATIVE INCIDENCE OF POUCHITIS AND POUCH-RELATED COMPLICATIONS IN PEDIATRIC PATIENTS WITH ULCERATIVE COLITIS
THE CUMULATIVE INCIDENCE OF POUCHITIS AND POUCH-RELATED COMPLICATIONS IN PEDIATRIC PATIENTS WITH ULCERATIVE COLITIS Open
Background & Aims Despite highly effective therapies, many children develop medically refractory ulcerative colitis (UC) and undergo proctocolectomy with ileal pouch anal anastomosis (IPAA). There is little real world evidence regarding IP…
View article: Total Abdominal Colectomies With Proctectomy Are Associated With Higher 30-Day Readmission Rates in Children With Ulcerative Colitis
Total Abdominal Colectomies With Proctectomy Are Associated With Higher 30-Day Readmission Rates in Children With Ulcerative Colitis Open
Background Hospital readmissions are a burden on patients and families and place financial strain on the health care system. Thirty-day readmission rates for adult patients undergoing colectomy are as high as 30%, and inflammatory bowel di…
4 TOTAL ABDOMINAL COLECTOMIES WITH PROCTECTOMY ARE ASSOCIATED WITH HIGHER 30-DAY READMISSION RATES IN CHILDREN WITH ULCERATIVE COLITIS Open
Background Hospital readmissions are frequent and expensive. Thirty-day readmission rates for adult patients undergoing colectomy are as high as 25%, with inflammatory bowel disease (IBD) being a major risk factor for readmission. We sough…
Weekend Surgical Admissions of Pediatric IBD Patients Have a Higher Risk of Complication in Hospitals Across the US Open
Surgical admissions occurring over the weekend have worse clinical outcomes compared with weekday admissions. This study is the first to demonstrate weekend admission as an independent risk factor for in-hospital complication in both pedia…
View article: Thrombotic and Infectious Risks of Parenteral Nutrition in Hospitalized Pediatric Inflammatory Bowel Disease
Thrombotic and Infectious Risks of Parenteral Nutrition in Hospitalized Pediatric Inflammatory Bowel Disease Open
Hospitalized pediatric IBD patients, particularly surgical, receiving PN are at increased risk for thrombosis and infection. Clinicians must balance these risks with the benefits of PN.
View article: Effectiveness of oral iron supplementation in treatment of anemia associated with pediatric ulcerative colitis flare
Effectiveness of oral iron supplementation in treatment of anemia associated with pediatric ulcerative colitis flare Open
Iron deficiency anemia (IDA) is the most prevalent extraintestinal laboratory manifestation observed in patients with inflammatory bowel diseases (IBD), including ulcerative colitis (UC), and Crohn disease (CD).1 IDA is more prevalent in c…
View article: Improving Quality in the Care of Patients with Inflammatory Bowel Diseases
Improving Quality in the Care of Patients with Inflammatory Bowel Diseases Open
Efforts to improve healthcare quality were firmly established before the Institute of Medicine (IOM) historic 2000 and 2001 reports, To Err is Human Building a Safer Health System and Crossing the Quality Chasm: A New Health System for the…
View article: 1 EFFECTIVENESS OF ORAL IRON SUPPLEMENTATION IN THE TREATMENT OF ANEMIA ASSOCIATED WITH PEDIATRIC ULCERATIVE COLITIS FLARE
1 EFFECTIVENESS OF ORAL IRON SUPPLEMENTATION IN THE TREATMENT OF ANEMIA ASSOCIATED WITH PEDIATRIC ULCERATIVE COLITIS FLARE Open
Iron deficiency anemia (IDA) is the most prevalent extra-intestinal sequelae of pediatric inflammatory bowel disease. As IV iron therapy options expand, use of oral iron supplementation (oral Fe) to treat IDA in the presence of increased u…