Matthew Hinderman
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View article: A PP2A molecular glue overcomes RAS/MAPK inhibitor resistance in KRAS-mutant non–small cell lung cancer
A PP2A molecular glue overcomes RAS/MAPK inhibitor resistance in KRAS-mutant non–small cell lung cancer Open
The effectiveness of RAS/MAPK inhibitors in treating metastatic KRAS-mutant non-small cell lung cancer (NSCLC) is often hindered by the development of resistance driven by disrupted negative feedback mechanisms led by phosphatases like PP2…
View article: Supp Figure 6 from Mutant PP2A Induces IGFBP2 Secretion to Promote Development of High-Grade Uterine Cancer
Supp Figure 6 from Mutant PP2A Induces IGFBP2 Secretion to Promote Development of High-Grade Uterine Cancer Open
Supp Figure 6
View article: Supp Figure 4 from Mutant PP2A Induces IGFBP2 Secretion to Promote Development of High-Grade Uterine Cancer
Supp Figure 4 from Mutant PP2A Induces IGFBP2 Secretion to Promote Development of High-Grade Uterine Cancer Open
Supp Figure 4
View article: B56-alpha OE Vector Map from Mutant PP2A Induces IGFBP2 Secretion to Promote Development of High-Grade Uterine Cancer
B56-alpha OE Vector Map from Mutant PP2A Induces IGFBP2 Secretion to Promote Development of High-Grade Uterine Cancer Open
Vector map for the B56-alpha overexpression (OE) plasmid
View article: Supp Figure 12 from Mutant PP2A Induces IGFBP2 Secretion to Promote Development of High-Grade Uterine Cancer
Supp Figure 12 from Mutant PP2A Induces IGFBP2 Secretion to Promote Development of High-Grade Uterine Cancer Open
Supp Figure 12
View article: Supp Figure 1 from Mutant PP2A Induces IGFBP2 Secretion to Promote Development of High-Grade Uterine Cancer
Supp Figure 1 from Mutant PP2A Induces IGFBP2 Secretion to Promote Development of High-Grade Uterine Cancer Open
Supp Figure 1
View article: Supp Figure 7 from Mutant PP2A Induces IGFBP2 Secretion to Promote Development of High-Grade Uterine Cancer
Supp Figure 7 from Mutant PP2A Induces IGFBP2 Secretion to Promote Development of High-Grade Uterine Cancer Open
Supp Figure 7
View article: Supp Figure 10 from Mutant PP2A Induces IGFBP2 Secretion to Promote Development of High-Grade Uterine Cancer
Supp Figure 10 from Mutant PP2A Induces IGFBP2 Secretion to Promote Development of High-Grade Uterine Cancer Open
Supp Figure 10
View article: Supp Figure 8 from Mutant PP2A Induces IGFBP2 Secretion to Promote Development of High-Grade Uterine Cancer
Supp Figure 8 from Mutant PP2A Induces IGFBP2 Secretion to Promote Development of High-Grade Uterine Cancer Open
Supp Figure 8
View article: TCGA Patient IDs from Mutant PP2A Induces IGFBP2 Secretion to Promote Development of High-Grade Uterine Cancer
TCGA Patient IDs from Mutant PP2A Induces IGFBP2 Secretion to Promote Development of High-Grade Uterine Cancer Open
Patient IDs used for all TCGA analysis used in this manuscript
View article: Supp Figure 3 from Mutant PP2A Induces IGFBP2 Secretion to Promote Development of High-Grade Uterine Cancer
Supp Figure 3 from Mutant PP2A Induces IGFBP2 Secretion to Promote Development of High-Grade Uterine Cancer Open
Supp Figure 3
View article: Raw PCA Data from Mutant PP2A Induces IGFBP2 Secretion to Promote Development of High-Grade Uterine Cancer
Raw PCA Data from Mutant PP2A Induces IGFBP2 Secretion to Promote Development of High-Grade Uterine Cancer Open
Raw data of the PCA analysis from the Broad Institute Cell Line Encyclopedia
View article: Supp Figure 11 from Mutant PP2A Induces IGFBP2 Secretion to Promote Development of High-Grade Uterine Cancer
Supp Figure 11 from Mutant PP2A Induces IGFBP2 Secretion to Promote Development of High-Grade Uterine Cancer Open
Supp Figure 11
View article: Data from Mutant PP2A Induces IGFBP2 Secretion to Promote Development of High-Grade Uterine Cancer
Data from Mutant PP2A Induces IGFBP2 Secretion to Promote Development of High-Grade Uterine Cancer Open
Uterine serous carcinoma (USC) and uterine carcinosarcoma (UCS) tumors are uniquely aggressive, suggesting that the primary tumor is intrinsically equipped to disseminate and metastasize. Previous work identified mutational hotspots within…
View article: Supp Figure 5 from Mutant PP2A Induces IGFBP2 Secretion to Promote Development of High-Grade Uterine Cancer
Supp Figure 5 from Mutant PP2A Induces IGFBP2 Secretion to Promote Development of High-Grade Uterine Cancer Open
Supp Figure 5
View article: Supp Figure 9 from Mutant PP2A Induces IGFBP2 Secretion to Promote Development of High-Grade Uterine Cancer
Supp Figure 9 from Mutant PP2A Induces IGFBP2 Secretion to Promote Development of High-Grade Uterine Cancer Open
Supp Figure 9
View article: Supplementary Figure Legends from Mutant PP2A Induces IGFBP2 Secretion to Promote Development of High-Grade Uterine Cancer
Supplementary Figure Legends from Mutant PP2A Induces IGFBP2 Secretion to Promote Development of High-Grade Uterine Cancer Open
Supplementary Figure Legends
View article: Supp Figure 2 from Mutant PP2A Induces IGFBP2 Secretion to Promote Development of High-Grade Uterine Cancer
Supp Figure 2 from Mutant PP2A Induces IGFBP2 Secretion to Promote Development of High-Grade Uterine Cancer Open
Supp Figure 2
View article: EGFP OE Vector Map from Mutant PP2A Induces IGFBP2 Secretion to Promote Development of High-Grade Uterine Cancer
EGFP OE Vector Map from Mutant PP2A Induces IGFBP2 Secretion to Promote Development of High-Grade Uterine Cancer Open
Vector map for the EGFP overexpression (OE) plasmid
View article: IDEXX Cell Line Verification from Mutant PP2A Induces IGFBP2 Secretion to Promote Development of High-Grade Uterine Cancer
IDEXX Cell Line Verification from Mutant PP2A Induces IGFBP2 Secretion to Promote Development of High-Grade Uterine Cancer Open
Verification of cell lines employed in this manuscript.
View article: Key Resources Table from Mutant PP2A Induces IGFBP2 Secretion to Promote Development of High-Grade Uterine Cancer
Key Resources Table from Mutant PP2A Induces IGFBP2 Secretion to Promote Development of High-Grade Uterine Cancer Open
table of key resources and reagents used in this manuscript.