Matthew I. Kim
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View article: Patient-reported symptom relief from percutaneous benign thyroid nodule radiofrequency ablation in routine clinical care
Patient-reported symptom relief from percutaneous benign thyroid nodule radiofrequency ablation in routine clinical care Open
RFA＝ radiofrequency ablation; BTN＝ benign thyroid nodule; VAS＝ visual analog scale; VRR＝ volume reduction ratio; TSH = thyroid stimulating hormone; LA＝ laser ablation; MWA＝ microwave ablation.
View article: Differential Growth Rates of Benign vs. Malignant Thyroid Nodules
Differential Growth Rates of Benign vs. Malignant Thyroid Nodules Open
Malignant nodules, especially higher-risk phenotypes, grow faster than benign nodules. As growth >2 mm/y predicts malignant compared with benign disease, this clinical parameter can contribute to the assessment of thyroid cancer risk.
View article: Qualifiers of atypia in the cytologic diagnosis of thyroid nodules are associated with different Afirma gene expression classifier results and clinical outcomes
Qualifiers of atypia in the cytologic diagnosis of thyroid nodules are associated with different Afirma gene expression classifier results and clinical outcomes Open
BACKGROUND Thyroid nodules with atypia of undetermined significance (AUS) on fine‐needle aspiration (FNA) have a low risk of malignancy that appears to vary based on specific features described in the AUS diagnosis. The Afirma gene express…
View article: Long- versus short-interval follow-up of cytologically benign thyroid nodules: a prospective cohort study
Long- versus short-interval follow-up of cytologically benign thyroid nodules: a prospective cohort study Open
While expert opinion currently recommends repeat evaluation of a cytologically benign nodule at 1-2 years, these are the first data to demonstrate that this interval can be safely extended to 3 years without increased mortality or patient …
View article: Bethesda Categorization of Thyroid Nodule Cytology and Prediction of Thyroid Cancer Type and Prognosis
Bethesda Categorization of Thyroid Nodule Cytology and Prediction of Thyroid Cancer Type and Prognosis Open
In addition to predicting cancer prevalence, the TBS also imparts important prognostic information about cancer type, variant, and risk of recurrence. These data extend the utility of TBS classification by fostering an improved understandi…
View article: The Influence of Patient Age on Thyroid Nodule Formation, Multinodularity, and Thyroid Cancer Risk
The Influence of Patient Age on Thyroid Nodule Formation, Multinodularity, and Thyroid Cancer Risk Open
With advancing age, the prevalence of clinically relevant thyroid nodules increases, whereas the risk that such nodules are malignant decreases. Nonetheless, when thyroid cancer is detected in older individuals, a higher-risk histological …
View article: Afirma Benign Thyroid Nodules Show Similar Growth to Cytologically Benign Nodules During Follow-Up
Afirma Benign Thyroid Nodules Show Similar Growth to Cytologically Benign Nodules During Follow-Up Open
Cyto-I/GEC-B nodules demonstrate similar growth to Cyto-B nodules during follow-up. Although Cyto-I/GEC-B nodules were more frequently resected, only one malignancy was found. These data suggest that reassessment of Cyto-I/GEC-B nodules ma…
View article: The variable phenotype and low-risk nature of RAS-positive thyroid nodules
The variable phenotype and low-risk nature of RAS-positive thyroid nodules Open
While RAS-oncogene mutations increase malignancy risk, these data demonstrate a low-risk phenotype for most RAS-positive cancers. Furthermore, cytologically benign, yet RAS-positive nodules behave in an indolent fashion over years. RAS-pos…