Matthew J. Dysart
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View article: Cross-order detection of bacteriophage transduction in communities using ribosomal RNA barcoding
Cross-order detection of bacteriophage transduction in communities using ribosomal RNA barcoding Open
Bacteriophages (phages) facilitate gene transfer and microbial evolution in all ecosystems and have applications as tools for engineering microbiomes and as antimicrobials. Historic efforts to map phage hosts, such as plaque assays, are li…
View article: Controlling the taxonomic composition of biological information storage in 16S ribosomal RNA
Controlling the taxonomic composition of biological information storage in 16S ribosomal RNA Open
Microbes can be programmed to record participation in gene transfer by coding biological-recording devices into mobile DNA. Upon DNA uptake, these devices transcribe a catalytic RNA (cat-RNA) that binds to conserved sequences within riboso…
View article: PLS3 missense variants affecting the actin-binding domains cause X-linked congenital diaphragmatic hernia and body-wall defects
PLS3 missense variants affecting the actin-binding domains cause X-linked congenital diaphragmatic hernia and body-wall defects Open
Congenital diaphragmatic hernia (CDH) is a relatively common and genetically heterogeneous structural birth defect associated with high mortality and morbidity. We describe eight unrelated families with an X-linked condition characterized …
View article: Information storage across a microbial community using universal RNA memory
Information storage across a microbial community using universal RNA memory Open
Biological recorders can code information in DNA, but they remain challenging to apply in complex microbial communities. To program microbiome information storage, a synthetic catalytic RNA (cat-RNA) was used to write information in riboso…
View article: Missense variants affecting the actin-binding domains of <i>PLS3</i> cause X-linked congenital diaphragmatic hernia and body wall defects
Missense variants affecting the actin-binding domains of <i>PLS3</i> cause X-linked congenital diaphragmatic hernia and body wall defects Open
Congenital diaphragmatic hernia (CDH) is a relatively common and genetically heterogeneous structural birth defect associated with high mortality and morbidity. We describe eight unrelated families with a novel X-linked condition character…