Matthew Read
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View article: Parsimonious Dataset Construction for Laparoscopic Cholecystectomy Structure Segmentation
Parsimonious Dataset Construction for Laparoscopic Cholecystectomy Structure Segmentation Open
Labeling has always been expensive in the medical context, which has hindered related deep learning application. Our work introduces active learning in surgical video frame selection to construct a high-quality, affordable Laparoscopic Cho…
View article: A Standardized Nontargeted Metabolomics Analytical Method for Qualitatively Comparing Apples to Apples
A Standardized Nontargeted Metabolomics Analytical Method for Qualitatively Comparing Apples to Apples Open
Food composition has been traditionally defined by 35-160 chemical components with established nutritional significance for human health. Modern omics technologies have revealed that the chemical complexity of food is far greater, offering…
View article: 771. EVOLUTION OF THE SURGICAL MANAGEMENT OF OESOPHAGEAL PERFORATION
771. EVOLUTION OF THE SURGICAL MANAGEMENT OF OESOPHAGEAL PERFORATION Open
Background Oesophageal perforations historically have been managed with open trans-thoracic operations. With the increasing experience of minimally invasive procedures, we have performed a case series of trans-hiatal repairs for oesophagea…
View article: Effect of laparoscopic sleeve gastrectomy versus laparoscopic Roux‐en‐Y gastric bypass on body composition
Effect of laparoscopic sleeve gastrectomy versus laparoscopic Roux‐en‐Y gastric bypass on body composition Open
Background There is limited data with respect to body composition changes for laparoscopic sleeve gastrectomy (SG) and laparoscopic Roux‐en‐Y gastric bypass (RYGB). The objective of this study was to analyse changes in body composition bet…
View article: DDA: Dimensionality Driven Augmentation Search for Contrastive Learning in Laparoscopic Surgery
DDA: Dimensionality Driven Augmentation Search for Contrastive Learning in Laparoscopic Surgery Open
Self-supervised learning (SSL) has potential for effective representation learning in medical imaging, but the choice of data augmentation is critical and domain-specific. It remains uncertain if general augmentation policies suit surgical…
View article: Using neural networks to autonomously assess adequacy in intraoperative cholangiograms
Using neural networks to autonomously assess adequacy in intraoperative cholangiograms Open
View article: Current status and clinical applications of tissue engineering of the gastrointestinal tract: a systematized narrative review
Current status and clinical applications of tissue engineering of the gastrointestinal tract: a systematized narrative review Open
Background Since the advent of regenerative medicine, tissue engineering of the gastrointestinal tract (GIT) has been extensively studied in laboratory animals and humans. Various biologic scaffolds and cell sources have been trialed to re…
View article: Effect of timing of perioperative chemical thromboprophylaxis on thromboembolic, bleeding, and other complications during and after antireflux surgery: multicentre cohort study
Effect of timing of perioperative chemical thromboprophylaxis on thromboembolic, bleeding, and other complications during and after antireflux surgery: multicentre cohort study Open
Background Although guidelines recommend the use of perioperative chemical thromboprophylaxis for antireflux surgery, the optimal timing for its initiation is unknown. The aim of this study was to investigate whether perioperative timing o…
View article: Inhibition of BMP2 and BMP4 Represses Barrett’s Esophagus While Enhancing the Regeneration of Squamous Epithelium in Preclinical Models
Inhibition of BMP2 and BMP4 Represses Barrett’s Esophagus While Enhancing the Regeneration of Squamous Epithelium in Preclinical Models Open
View article: C-reactive protein is a predictor of severe infective complications following gastrectomy—a retrospective analysis
C-reactive protein is a predictor of severe infective complications following gastrectomy—a retrospective analysis Open
CRP is a strong negative predicter of SI complications following gastrectomy. This suggests early CRP values may be useful in prompting early investigation or facilitating safer, earlier discharge from hospital. Health services may benefit…
View article: Percentage of intrathoracic stomach predicts operative and post-operative morbidity, persistent reflux and PPI requirement following laparoscopic hiatus hernia repair and fundoplication
Percentage of intrathoracic stomach predicts operative and post-operative morbidity, persistent reflux and PPI requirement following laparoscopic hiatus hernia repair and fundoplication Open
View article: Selective targeting BMP2 and 4 in SMAD4 negative esophageal adenocarcinoma inhibits tumor growth and aggressiveness in preclinical models
Selective targeting BMP2 and 4 in SMAD4 negative esophageal adenocarcinoma inhibits tumor growth and aggressiveness in preclinical models Open
View article: Body Composition Differences Between Excess Weight Loss ≥ 50% and < 50% at 12 Months Following Bariatric Surgery
Body Composition Differences Between Excess Weight Loss ≥ 50% and < 50% at 12 Months Following Bariatric Surgery Open
View article: Predicting Response to Neoadjuvant Therapy in Oesophageal Adenocarcinoma
Predicting Response to Neoadjuvant Therapy in Oesophageal Adenocarcinoma Open
(1) Background: Oesophageal cancers are often late-presenting and have a poor 5-year survival rate. The standard treatment of oesophageal adenocarcinomas involves neoadjuvant chemotherapy with or without radiotherapy followed by surgery. H…
View article: Fully Covered Expandable Metal Stent for Early, Definitive Endoscopic Management of Bile Duct Injury
Fully Covered Expandable Metal Stent for Early, Definitive Endoscopic Management of Bile Duct Injury Open
View article: O-B05 Does rapid or gradual weight loss following bariatric surgery affect lean body mass depreciation?
O-B05 Does rapid or gradual weight loss following bariatric surgery affect lean body mass depreciation? Open
Background Controversy exists regarding the influence of the rate of weight loss on long-term body composition. The objective of this study was to compare body composition changes in patients with successful and unsuccessful weight loss 12…
View article: Molecular and genomic characterisation of a panel of human anal cancer cell lines
Molecular and genomic characterisation of a panel of human anal cancer cell lines Open
View article: Robotic-assisted minimally invasive esophagectomy (RAMIE) for esophageal cancer training curriculum—a worldwide Delphi consensus study
Robotic-assisted minimally invasive esophagectomy (RAMIE) for esophageal cancer training curriculum—a worldwide Delphi consensus study Open
Summary Background Structured training protocols can safely improve skills prior initiating complex surgical procedures such as robotic-assisted minimally invasive esophagectomy (RAMIE). As no consensus on a training curriculum for RAMIE h…
View article: Comparison of short-term outcomes from the International Oesophago-Gastric Anastomosis Audit (OGAA), the Esophagectomy Complications Consensus Group (ECCG), and the Dutch Upper Gastrointestinal Cancer Audit (DUCA)
Comparison of short-term outcomes from the International Oesophago-Gastric Anastomosis Audit (OGAA), the Esophagectomy Complications Consensus Group (ECCG), and the Dutch Upper Gastrointestinal Cancer Audit (DUCA) Open
Background The Esophagectomy Complications Consensus Group (ECCG) and the Dutch Upper Gastrointestinal Cancer Audit (DUCA) have set standards in reporting outcomes after oesophagectomy. Reporting outcomes from selected high-volume centres …
View article: Surgical management of a perforated ‘black oesophagus’
Surgical management of a perforated ‘black oesophagus’ Open
Contains fulltext : 245236.pdf (Publisher’s version ) (Open Access)
View article: Supplementary Material for: Worldwide Practice in Gastric Cancer Surgery: A 6-Year Update
Supplementary Material for: Worldwide Practice in Gastric Cancer Surgery: A 6-Year Update Open
Objectives: The aim of the study was to evaluate the current status of gastric cancer surgery worldwide and update the changes compared to a previous survey in 2014. Methods: A cross-sectional survey was sent to…
View article: Worldwide Practice in Gastric Cancer Surgery: A 6-Year Update
Worldwide Practice in Gastric Cancer Surgery: A 6-Year Update Open
Objectives: The aim of the study was to evaluate the current status of gastric cancer surgery worldwide and update the changes compared to a previous survey in 2014. Methods: A cross-sectional survey was sent to…
View article: A standardized approach for the thoracic dissection in robotic-assisted minimally invasive esophagectomy (RAMIE)
A standardized approach for the thoracic dissection in robotic-assisted minimally invasive esophagectomy (RAMIE) Open
Robot-assisted minimally invasive esophagectomy (RAMIE) is increasingly being adopted as the preferred surgical treatment for esophageal cancer, as it is superior to open esophagectomy and a good alternative to conventional minimally invas…
View article: Rethinking gastroesophageal reflux disorder
Rethinking gastroesophageal reflux disorder Open
Gastroesophageal reflux disease (GERD) is a common clinical condition for which our understanding has evolved over the past decades. It is now considered a cluster of phenotypes with numerous anatomical and physiological abnormalities cont…
View article: The role of esophagectomy in the management of Barrett's esophagus with high‐grade dysplasia
The role of esophagectomy in the management of Barrett's esophagus with high‐grade dysplasia Open
Barrett's esophagus (BE) with high‐grade dysplasia (HGD) has previously been a routine indication for esophagectomy. Recent advances in endoscopic therapy have resulted in a shift away from surgery. Current international guidelines recomme…
View article: Perioperative screening, management, and surveillance of Barrett's esophagus in bariatric surgical patients
Perioperative screening, management, and surveillance of Barrett's esophagus in bariatric surgical patients Open
Obesity is a strong risk factor for Barrett's esophagus (BE), the only proven precursor lesion to esophageal adenocarcinoma (EAC). Bariatric surgery is currently the only reliable treatment that achieves long‐term sustained weight loss; ho…
View article: Recent insights into the biology of Barrett's esophagus
Recent insights into the biology of Barrett's esophagus Open
Barrett's esophagus (BE) is the only known precursor to esophageal adenocarcinoma (EAC), an aggressive cancer with a poor prognosis. Our understanding of the pathogenesis and Barrett's metaplasia is incomplete, and this has limited the dev…
View article: Delayed presentation of breast necrotising fasciitis due to <scp>COVID</scp>‐19 anxiety
Delayed presentation of breast necrotising fasciitis due to <span>COVID</span>‐19 anxiety Open
A 47-year-old lady presented to the emergency department via ambulance with a month-long history of worsening right breast cellulitis and discharge from a periareolar abscess. Her significant past history included a breast abscess managed …
View article: Preclinical models for the study of Barrett's carcinogenesis
Preclinical models for the study of Barrett's carcinogenesis Open
Barrett's esophagus (BE) is clinically significant, as it is the only known precursor lesion for esophageal adenocarcinoma. To develop improved therapies for the treatment of BE, a greater understanding of the disease process at the molecu…
View article: Inhibiting the system xC−/glutathione axis selectively targets cancers with mutant-p53 accumulation
Inhibiting the system xC−/glutathione axis selectively targets cancers with mutant-p53 accumulation Open