Matthew J. Robertson
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View article: The Effects of Reference Dependence on Judicial Persuasion
The Effects of Reference Dependence on Judicial Persuasion Open
I study a model of persuasion in which a loss‐averse judge has reference‐dependent preferences. When the loss from wrongful conviction looms largest, the outcome that forms the judge's reference point has significant implications for the e…
View article: DsiRNA Knockdowns of the Hippo Pathway Regulators Promote Cardiac Myocyte Replication
DsiRNA Knockdowns of the Hippo Pathway Regulators Promote Cardiac Myocyte Replication Open
In the event of a heart attack, many cardiac myocytes are irreversibly lost and cannot be replaced, which can lead to heart failure. Several investigations have proved that the Hippo pathway can be manipulated to benefit cardiac myocyte re…
View article: Procurement with competing insiders
Procurement with competing insiders Open
View article: Competitive outcomes in a Cournot-Tullock contest
Competitive outcomes in a Cournot-Tullock contest Open
View article: Outcome of Subsequent Therapies After <sup>177</sup>Lu‐Vipivotide Tetraxetan for Metastatic Castrate‐Resistant Prostate Cancer: A Tertiary Cancer Center Experience
Outcome of Subsequent Therapies After <sup>177</sup>Lu‐Vipivotide Tetraxetan for Metastatic Castrate‐Resistant Prostate Cancer: A Tertiary Cancer Center Experience Open
Background 177 Lu‐vipivotide tetraxetan ( 177 Lu‐PSMA‐617, LuPSMA) improves overall survival in patients with metastatic castration‐resistant prostate cancer (mCRPC) after at least one taxane chemotherapy and androgen receptor pathway inhi…
View article: Metastatic Melanoma to Ovary and Advances in Metastatic Melanoma Treatment: A Case Report
Metastatic Melanoma to Ovary and Advances in Metastatic Melanoma Treatment: A Case Report Open
View article: Sequential elimination in multi-stage all-pay auctions
Sequential elimination in multi-stage all-pay auctions Open
I study a multi-stage all-pay auction in which the lowest bidder in each stage is eliminated. Elimination continues until only two bidders remain, one of whom wins the auction. I analyse optimal bidding behaviour and the seller's expected …
View article: Author response: Downregulation of Mirlet7 miRNA family promotes Tc17 differentiation and emphysema via de-repression of RORγt
Author response: Downregulation of Mirlet7 miRNA family promotes Tc17 differentiation and emphysema via de-repression of RORγt Open
View article: Downregulation of Mirlet7 miRNA family promotes Tc17 differentiation and emphysema via de-repression of RORγt
Downregulation of Mirlet7 miRNA family promotes Tc17 differentiation and emphysema via de-repression of RORγt Open
Environmental air irritants including nanosized carbon black (nCB) can drive systemic inflammation, promoting chronic obstructive pulmonary disease (COPD) and emphysema development. The let-7 microRNA ( Mirlet7 miRNA) family is associated …
View article: Reviewer #2 (Public Review): Downregulation of Let-7 miRNA promotes Tc17 differentiation and emphysema via de-repression of RORγt
Reviewer #2 (Public Review): Downregulation of Let-7 miRNA promotes Tc17 differentiation and emphysema via de-repression of RORγt Open
Environmental air irritants including nanosized carbon black (nCB) can drive systemic inflammation, promoting chronic obstructive pulmonary disease (COPD) and emphysema development. The let-7 family of miRNAs is associated with IL-17-drive…
View article: Reviewer #1 (Public Review): Downregulation of Let-7 miRNA promotes Tc17 differentiation and emphysema via de-repression of RORγt
Reviewer #1 (Public Review): Downregulation of Let-7 miRNA promotes Tc17 differentiation and emphysema via de-repression of RORγt Open
Environmental air irritants including nanosized carbon black (nCB) can drive systemic inflammation, promoting chronic obstructive pulmonary disease (COPD) and emphysema development. The let-7 family of miRNAs is associated with IL-17-drive…
View article: Author response: Downregulation of Let-7 miRNA promotes Tc17 differentiation and emphysema via de-repression of RORγt
Author response: Downregulation of Let-7 miRNA promotes Tc17 differentiation and emphysema via de-repression of RORγt Open
Environmental air irritants including nanosized carbon black (nCB) can drive systemic inflammation, promoting chronic obstructive pulmonary disease (COPD) and emphysema development. The let-7 family of miRNAs is associated with IL-17-drive…
View article: Downregulation of Let-7 miRNA promotes Tc17 differentiation and emphysema via de-repression of RORγt
Downregulation of Let-7 miRNA promotes Tc17 differentiation and emphysema via de-repression of RORγt Open
Environmental air irritants including nanosized carbon black (nCB) can drive systemic inflammation, promoting chronic obstructive pulmonary disease (COPD) and emphysema development. The let-7 family of miRNAs is associated with IL-17-drive…
View article: Downregulation of Mirlet7 miRNA family promotes Tc17 differentiation and emphysema via de-repression of RORγt
Downregulation of Mirlet7 miRNA family promotes Tc17 differentiation and emphysema via de-repression of RORγt Open
Environmental air irritants including nanosized carbon black (nCB) can drive systemic inflammation, promoting chronic obstructive pulmonary disease (COPD) and emphysema development. The let-7 microRNA ( Mirlet7 miRNA) family is associated …
View article: Reviewer #1 (Public Review): Downregulation of Let-7 miRNA promotes Tc17 differentiation and emphysema via de-repression of RORγt
Reviewer #1 (Public Review): Downregulation of Let-7 miRNA promotes Tc17 differentiation and emphysema via de-repression of RORγt Open
Environmental air irritants including nanosized carbon black (nCB) can drive systemic inflammation, promoting chronic obstructive pulmonary disease (COPD) and emphysema development. The let-7 family of miRNAs is associated with IL-17-drive…
View article: Reviewer #2 (Public Review): Downregulation of Let-7 miRNA promotes Tc17 differentiation and emphysema via de-repression of RORγt
Reviewer #2 (Public Review): Downregulation of Let-7 miRNA promotes Tc17 differentiation and emphysema via de-repression of RORγt Open
Environmental air irritants including nanosized carbon black (nCB) can drive systemic inflammation, promoting chronic obstructive pulmonary disease (COPD) and emphysema development. The let-7 family of miRNAs is associated with IL-17-drive…
View article: Reviewer #3 (Public Review): Downregulation of Let-7 miRNA promotes Tc17 differentiation and emphysema via de-repression of RORγt
Reviewer #3 (Public Review): Downregulation of Let-7 miRNA promotes Tc17 differentiation and emphysema via de-repression of RORγt Open
Environmental air irritants including nanosized carbon black (nCB) can drive systemic inflammation, promoting chronic obstructive pulmonary disease (COPD) and emphysema development. The let-7 family of miRNAs is associated with IL-17-drive…
View article: Downregulation of Let-7 miRNA promotes Tc17 differentiation and emphysema via de-repression of RORγt
Downregulation of Let-7 miRNA promotes Tc17 differentiation and emphysema via de-repression of RORγt Open
Environmental air irritants including nanosized carbon black (nCB) can drive systemic inflammation, promoting chronic obstructive pulmonary disease (COPD) and emphysema development. The let-7 family of miRNAs is associated with IL-17-drive…
View article: Unobservable costly effort in security design
Unobservable costly effort in security design Open
I introduce unobservable costly effort into the canonical signalling model of security design. The choice of effort determines the quality of the security and creates an additional optimisation problem the firm must solve. My main result i…
View article: Downregulation of <i>Let-7</i> miRNA promotes Tc17 differentiation and emphysema via de-repression of RORγt
Downregulation of <i>Let-7</i> miRNA promotes Tc17 differentiation and emphysema via de-repression of RORγt Open
Environmental air irritants including nanosized carbon black (nCB) can drive systemic inflammation, promoting chronic obstructive pulmonary disease (COPD) and emphysema development. The let-7 family of miRNAs is associated with IL-17-drive…
View article: Loss of cytochrome P450 (CYP)1B1 mitigates hyperoxia response in adult mouse lung by reprogramming metabolism and translation
Loss of cytochrome P450 (CYP)1B1 mitigates hyperoxia response in adult mouse lung by reprogramming metabolism and translation Open
Oxygen supplementation is life saving for premature infants and for COVID-19 patients but can induce long-term pulmonary injury by triggering inflammation, with xenobiotic-metabolizing CYP enzymes playing a critical role. Murine studies sh…
View article: Supplementary Table S2 from Multi-omics Integration Analysis Robustly Predicts High-Grade Patient Survival and Identifies CPT1B Effect on Fatty Acid Metabolism in Bladder Cancer
Supplementary Table S2 from Multi-omics Integration Analysis Robustly Predicts High-Grade Patient Survival and Identifies CPT1B Effect on Fatty Acid Metabolism in Bladder Cancer Open
Supplementary Table S2. List of gene-specific primers used for q-PCR.
View article: Supplementary Table S2 from Multi-omics Integration Analysis Robustly Predicts High-Grade Patient Survival and Identifies CPT1B Effect on Fatty Acid Metabolism in Bladder Cancer
Supplementary Table S2 from Multi-omics Integration Analysis Robustly Predicts High-Grade Patient Survival and Identifies CPT1B Effect on Fatty Acid Metabolism in Bladder Cancer Open
Supplementary Table S2. List of gene-specific primers used for q-PCR.
View article: Supplemental legend from Multi-omics Integration Analysis Robustly Predicts High-Grade Patient Survival and Identifies CPT1B Effect on Fatty Acid Metabolism in Bladder Cancer
Supplemental legend from Multi-omics Integration Analysis Robustly Predicts High-Grade Patient Survival and Identifies CPT1B Effect on Fatty Acid Metabolism in Bladder Cancer Open
Supplemental legend
View article: Supplementary Figure S8 from Multi-omics Integration Analysis Robustly Predicts High-Grade Patient Survival and Identifies CPT1B Effect on Fatty Acid Metabolism in Bladder Cancer
Supplementary Figure S8 from Multi-omics Integration Analysis Robustly Predicts High-Grade Patient Survival and Identifies CPT1B Effect on Fatty Acid Metabolism in Bladder Cancer Open
Supplementary Figure S8. A) FAO activity in BLCA cell lines upon CPTB overexpression. B) mRNA expression of ATP8B2 and PLA2G4C in patients with BLCA and BLCA cell lines of different grades. mRNA levels were normalized to GAPDH internal con…
View article: Supplementary Figure S5 from Multi-omics Integration Analysis Robustly Predicts High-Grade Patient Survival and Identifies CPT1B Effect on Fatty Acid Metabolism in Bladder Cancer
Supplementary Figure S5 from Multi-omics Integration Analysis Robustly Predicts High-Grade Patient Survival and Identifies CPT1B Effect on Fatty Acid Metabolism in Bladder Cancer Open
Supplementary Figure S5. A) Survival analysis of the upregulated (11/27) gene signature in high grade BLCA from the Kim, Lindgren, Sjodahl, and TCGA coherts. B) Survival analysis of the upregulated (11/27) gene signature in low grade BLCA …
View article: Data from The Prostate Cancer Androgen Receptor Cistrome in African American Men Associates with Upregulation of Lipid Metabolism and Immune Response
Data from The Prostate Cancer Androgen Receptor Cistrome in African American Men Associates with Upregulation of Lipid Metabolism and Immune Response Open
African-American (AA) men are more likely to be diagnosed with and die from prostate cancer than European American (EA) men. Despite the central role of the androgen receptor (AR) transcription factor in prostate cancer, little is known ab…
View article: Supplementary Table S7 from Multi-omics Integration Analysis Robustly Predicts High-Grade Patient Survival and Identifies CPT1B Effect on Fatty Acid Metabolism in Bladder Cancer
Supplementary Table S7 from Multi-omics Integration Analysis Robustly Predicts High-Grade Patient Survival and Identifies CPT1B Effect on Fatty Acid Metabolism in Bladder Cancer Open
Supplementary Table S7. Univariate and multivariate Cox proportional hazard regression models of the TCGA (A), Lindgren (B), Sjodahl (C), and Kim (D), data sets using CPT1B gene expression. Univariate Cox proportional hazard regression ana…
View article: Supplementary Tble S3 from Multi-omics Integration Analysis Robustly Predicts High-Grade Patient Survival and Identifies CPT1B Effect on Fatty Acid Metabolism in Bladder Cancer
Supplementary Tble S3 from Multi-omics Integration Analysis Robustly Predicts High-Grade Patient Survival and Identifies CPT1B Effect on Fatty Acid Metabolism in Bladder Cancer Open
Supplementary Table S3. Patient characteristics of bladder specimens used for the metabolomics and lipidomics profiling.
View article: Supplementary Figure S2 from Multi-omics Integration Analysis Robustly Predicts High-Grade Patient Survival and Identifies CPT1B Effect on Fatty Acid Metabolism in Bladder Cancer
Supplementary Figure S2 from Multi-omics Integration Analysis Robustly Predicts High-Grade Patient Survival and Identifies CPT1B Effect on Fatty Acid Metabolism in Bladder Cancer Open
Supplementary Figure S2. Chromatographic reproducibility of metabolomics of liver samples over three technical replicates identified by LC-MS using HILIC positive, HILIC negative, and reverse phase positive ionization modes. B) Chromatogra…