Explanipedia

Difficulty With Binary Voting Among FDA Oncology Advisory Committee Members Open

K Greenberg, Joseph M. Hopen, Muhammad Draw, Matthew S. McCoy, Genevieve P. Kanter , et al. · 2025

This qualitative study investigates the frequency of reports of difficulty in voting for drug approval by members of the Food and Drug Administration Oncologic Drugs Advisory Committee.

A Framework for Assessing the Permissibility of Academic Leaders’ Outside Activities Open

Matthew S. McCoy, Martha E. Gaines, Steven Joffe, Genevieve P. Kanter, Emily A. Largent , et al. · 2025

Policy Points Many have urged academic institutions to rethink conflict of interest policies governing leaders’ outside activities, which pose not only individual conflicts for leaders themselves but institutional conflicts for their acade…

Measuring Risks to Users' Health Privacy Posed by Third-Party Web Tracking and Targeted Advertising Open

Eric Zeng, Xiaoyuan Wu, Emily N. Ertmann, Lily Huang, David Johnson , et al. · 2025

A review of public comments submitted to the Centers for Medicare and Medicaid Services in response to the 2022 National Coverage Decision on treatment for Alzheimer’s disease Open

K Greenberg, Holly Fernandez Lynch, Chisom Nwakama, Jonathan Frumovitz, Samarth Setru , et al. · 2025

Alzheimer’s disease (AD) is a neurodegenerative disease with devastating personal and social consequences. In June 2021, the U.S. Food and Drug Administration (FDA) granted accelerated approval to aducanumab (Aduhelm; Biogen), a first-in-c…

What justifies public engagement in health financing decisions? Open

Matthew S. McCoy, Johan Dellgren, Ezekiel Emanuel · 2025

The World Bank's report, Open and inclusive: fair processes for financing universal health coverage, represents an important effort to specify the benefits and criteria of fair processes in health financing decisions. Here we argue …

Managing institutional conflicts: Stakeholder accounts of communication between conflict of interest and technology transfer offices Open

Matthew S. McCoy, Michaela Ward, Rebecca Neergaard, Steven Joffe, Julia E. Szymczak · 2024

There have been repeated calls for academic institutions to develop policies and procedures to manage institutional conflicts of interest (ICOI) arising from technology transfer activities. While prior research has examined adoption of ICO…

User Information Sharing and Hospital Website Privacy Policies Open

Matthew S. McCoy, Angela Ruohao Wu, Sam Burdyl, Y. Kim, Noell Kristen Smith , et al. · 2024

Importance Hospital websites frequently use tracking technologies that transfer user information to third parties. It is not known whether hospital websites include privacy policies that disclose relevant details regarding tracking. Object…

Vertebral Subluxation and Systems Biology: An Integrative Review Exploring the Salutogenic Influence of Chiropractic Care on the Neuroendocrine-Immune System Open

A L Haas, Jonathan Chung, Christopher Kent, Brooke Mills, Matthew S. McCoy · 2024

In this paper we synthesize an expansive body of literature examining the multifaceted influence of chiropractic care on processes within and modulators of the neuroendocrine-immune (NEI) system, for the purpose of generating an inductive …

Secondary Analysis of a Dataset to Estimate the Prevalence of Vertebral Subluxation and Its Implications for Health Promotion and Prevention Open

Christie Kwon, José Binongo, Matthew S. McCoy · 2023

Widespread Third-Party Tracking On Hospital Websites Poses Privacy Risks For Patients And Legal Liability For Hospitals Open

Ari B. Friedman, Raina M. Merchant, Amey Maley, Karim Farhat, Kristen Smith , et al. · 2023

Computer code that transfers data to third parties (third-party tracking) is common across the web and is subject to few federal privacy regulations. We determined the presence of potentially privacy-compromising data transfers to third pa…

Medical journals and advertiser tracking—Consequences for patients, clinicians, and editors Open

Ravi Gupta, Ari B. Friedman, Matthew S. McCoy · 2023

Medical journal websites frequently contain tracking code that transfers data about journal readers to third parties. These data give drug, device, and other medical product companies a potentially powerful resource for targeting advertise…

Association Between Nephrologist Ownership of Dialysis Facilities and Clinical Outcomes Open

Eugene Lin, Matthew S. McCoy, Yijie Liu, Khristina Lung, Derick Rapista , et al. · 2022

Importance Ownership of US dialysis facilities presents a financial conflict of interest for nephrologists, who may change their clinical practice to improve facility profitability. Objective To investigate the association between nephrolo…

Prevalence of Third-Party Tracking on Abortion Clinic Web Pages Open

Ari B. Friedman, Lujo Bauer, Rachel Gonzales, Matthew S. McCoy · 2022

This cross-sectional study assesses how often third-party domains use tracking data from visitors to abortion clinic web pages.

Ensuring Equitable Access to Dialysis: The Medicare Secondary Payer Act in Marietta Memorial Hospital Employee Health Benefit Plan v. DaVita, Inc. Open

George Maliha, Joel D. Glickman, Matthew S. McCoy · 2022

Although Medicare provides near-universal coverage for ESKD treatment in the United States, private insurers account for much of the profit margins of dialysis companies.1 This arrangement, which influences the distribution and availabilit…

Prevalence of Third-party Tracking on Medical Journal Websites Open

R. Gupta, Ari B. Friedman, Matthew S. McCoy · 2022

This cross-sectional study investigates web tracking prevalence and characteristics on medical journal websites.

Addressing Online Health Privacy Risks for Older Adults: A Perspective on Ethical Considerations and Recommendations Open

Ari B. Friedman, Chris Pathmanabhan, Allen Glicksman, George Demiris, Anne Rentoumis Cappola , et al. · 2022

The rise in online health information seeking among older adults promises significant benefits but also presents potentially serious privacy risks. In light of these risks, we argue that ongoing research and advocacy aimed at promoting onl…

What are the obligations of pharmaceutical companies in a global health emergency? Open

Ezekiel Emanuel, Allen Buchanan, Shuk Ying Chan, Cécile Fabre, Daniel Halliday , et al. · 2021

Historical trends in health care-related financial holdings among members of Congress Open

Matthew S. McCoy, Matthew Bonci, Steven Joffe, Genevieve P. Kanter · 2021

Background Revelations that some members of Congress, including members of key health care committees, hold substantial personal investments in the health care industry have raised concerns about lawmakers’ financial conflicts of interest …

What does it mean to engage the public in the response to covid-19? Open

Naomi Scheinerman, Matthew S. McCoy · 2021

Naomi Scheinerman and Matthew McCoy explain how governments and other authorities should respond to calls for public engagement in covid-19 response and recovery

Prevalence of Medical Journal Websites That Deny Access to Users Who Block Browser Cookies Open

Ari B. Friedman, Evan Miller, Matthew S. McCoy · 2021

This cross-sectional study of 1700 medical journal websites assesses the prevalence of journals denying access to website users who blocked browser cookies.

The limits of acceptable political influence over the FDA Open

Holly Fernandez Lynch, Steven Joffe, Matthew S. McCoy · 2021

Covax must go beyond proportional allocation of covid vaccines to ensure fair and equitable access Open

Lisa Herzog, Ole Frithjof Norheim, Ezekiel Emanuel, Matthew S. McCoy · 2021

International collaboration is key for the fair and efficient distribution of covid-19 vaccines. Lisa Herzog and colleagues' Fair Priority Model, with its focus on allocating vaccine based on limiting covid-19 harms, realises ethica…

On the Ethics of Vaccine Nationalism: The Case for the Fair Priority for Residents Framework Open

Ezekiel Emanuel, Allen Buchanan, Shuk Ying Chan, Cécile Fabre, Daniel Halliday , et al. · 2021

COVID-19 vaccines are likely to be scarce for years to come. Many countries, from India to the U.K., have demonstrated vaccine nationalism. What are the ethical limits to this vaccine nationalism? Neither extreme nationalism nor extreme co…

Public involvement in the governance of population-level biomedical research: unresolved questions and future directions Open

Sonja Erikainen, Phoebe Friesen, Leah Z. Rand, Karin Jongsma, Michael Dunn , et al. · 2020

Population-level biomedical research offers new opportunities to improve population health, but also raises new challenges to traditional systems of research governance and ethical oversight. Partly in response to these challenges, various…

Prevalence of Third-Party Tracking on COVID-19–Related Web Pages Open

Matthew S. McCoy, Timothy Libert, David G. Buckler, David Grande, Ari B. Friedman · 2020

This study uses webXray, an automated tool that detects tracking on websites, to describe the prevalence and characteristics of third-party data requests and cookies on the top 20 COVID-19–related websites, including academic and governmen…

An ethical framework for global vaccine allocation Open

Ezekiel Emanuel, Govind Persad, Adam L. Kern, Allen Buchanan, Cécile Fabre , et al. · 2020

The Fair Priority Model offers a practical way to fulfill pledges to distribute vaccines fairly and equitably

Patient and public involvement: Two sides of the same coin or different coins altogether? Open

Matthew S. McCoy, Jonathan Warsh, Leah Z. Rand, Michael Parker, Mark Sheehan · 2019

Patient and public involvement ( PPI ) has gained widespread support in health research and health policy circles, but there is little consensus on the precise meaning or justifications of PPI . We argue that an important step towards clar…

Addressing the Conflicts of Interest of Public Officials and Employees: Lessons From Cannabis Legalization Open

Matthew S. McCoy · 2019

"Addressing the Conflicts of Interest of Public Officials and Employees: Lessons From Cannabis Legalization." , 109(3), pp. 350–351

Campaign Contributions From Political Action Committees to Members of Congressional Committees Responding to the Opioid Crisis Open

Matthew S. McCoy, Genevieve P. Kanter · 2018

This study examines recent campaign contributions to members of US congressional committees responsible for legislating on the opioid crisis by political action committees (PACs) associated with firms under investigation for having contrib…

Industry Support of Patient Advocacy Organizations: The Case for an Extension of the Sunshine Act Provisions of the Affordable Care Act Open

Matthew S. McCoy · 2018

Patient advocacy organizations (PAOs) have long been regarded as important representatives of patient and caregiver interests in health policy debates. Recently, however, PAOs have attracted increased scrutiny over their financial ties to …

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