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View article: Early Biological Markers of Post-Acute Sequelae of SARS-CoV-2 Infection
Early Biological Markers of Post-Acute Sequelae of SARS-CoV-2 Infection Open
To understand the roles of acute phase viral dynamics and host immune responses in PASC, we enrolled 136 participants within 5 days of their first positive SARS-CoV-2 real-time PCR. Participants self-collected nasal specimens up to 21 time…
View article: Performance of Blood-Based Nucleocapsid Antigen Tests for Diagnosis of Severe Acute Respiratory Syndrome Coronavirus 2 Infection and Infectious Viral Shedding: A Systematic Review
Performance of Blood-Based Nucleocapsid Antigen Tests for Diagnosis of Severe Acute Respiratory Syndrome Coronavirus 2 Infection and Infectious Viral Shedding: A Systematic Review Open
Data on the performance of blood-based nucleocapsid antigen tests for diagnosing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and infectious viral shedding are limited. To address this knowledge gap, we conducted …
View article: Brain imaging signatures of neuropathic facial pain derived by artificial intelligence
Brain imaging signatures of neuropathic facial pain derived by artificial intelligence Open
Advances in neuroimaging have permitted the non-invasive examination of the human brain in pain. However, a persisting challenge is in the objective differentiation of neuropathic facial pain subtypes, as diagnosis is based on patients’ sy…
View article: Autoantigen profiling reveals a shared post-COVID signature in fully recovered and long COVID patients
Autoantigen profiling reveals a shared post-COVID signature in fully recovered and long COVID patients Open
Some individuals do not return to baseline health following SARS-CoV-2 infection, leading to a condition known as long COVID. The underlying pathophysiology of long COVID remains unknown. Given that autoantibodies have been found to play a…
View article: Autoantigen profiling reveals a shared post-COVID signature in fully recovered and Long COVID patients
Autoantigen profiling reveals a shared post-COVID signature in fully recovered and Long COVID patients Open
Some individuals do not return to baseline health following SARS-CoV-2 infection, leading to a condition known as Long COVID. The underlying pathophysiology of Long COVID remains unknown. Given that autoantibodies have been found to play a…
View article: Molecular mechanism of RIPK1 and caspase-8 in homeostatic type I interferon production and regulation
Molecular mechanism of RIPK1 and caspase-8 in homeostatic type I interferon production and regulation Open
Type I interferons (IFNs) are essential innate immune proteins that maintain tissue homeostasis through tonic expression and can be upregulated to drive antiviral resistance and inflammation upon stimulation. However, the mechanisms that i…
View article: Affective Brain-Computer Music Interface in Emotion Regulation and Neurofeedback: A Research Protocol
Affective Brain-Computer Music Interface in Emotion Regulation and Neurofeedback: A Research Protocol Open
Introduction: Emotion regulation is an integral part of mental health, dynamically impacting brain function as one’s emotions change continuously throughout the day. Impairments in emotion regulation are associated with a range of psychiat…
View article: From Science to Politics: COVID-19 Information Fatigue on YouTube
From Science to Politics: COVID-19 Information Fatigue on YouTube Open
Objective: The COVID-19 pandemic is the first pandemic where social media platforms relayed information on a large scale, enabling an “infodemic” of conflicting information which undermined the global response to the pandemic. Understandin…
View article: Examining the Use of Electroencephalography for the Diagnosis of Alzheimer’s Disease and Mild Cognitive Impairment
Examining the Use of Electroencephalography for the Diagnosis of Alzheimer’s Disease and Mild Cognitive Impairment Open
Introduction: Alzheimer’s disease is a type of dementia characterized by a buildup of -amyloid plaques and neurofibrillary tangles. Prior to the development of Alzheimer’s disease, patients may experience mild cognitive impairment, charact…
View article: bbolker/McMasterPandemic: updated Zenodo release
bbolker/McMasterPandemic: updated Zenodo release Open
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View article: Determination of Pharmacokinetic Parameters of a Four-Armed, Guanidinium-Rich Structurally Nanoengineered Antimicrobial Peptide Polymer: A Research Protocol
Determination of Pharmacokinetic Parameters of a Four-Armed, Guanidinium-Rich Structurally Nanoengineered Antimicrobial Peptide Polymer: A Research Protocol Open
Introduction: Antibacterial resistance has accentuated the need for the development of novel, efficacious pharmaceuticals. Structurally nanoengineered antimicrobial polypeptide polymers (SNAPPs) have shown promise as a candidate for a new …
View article: Memory resources recover gradually over time: The effects of word-frequency, presentation rate and list-composition on binding errors and mnemonic precision in source memory
Memory resources recover gradually over time: The effects of word-frequency, presentation rate and list-composition on binding errors and mnemonic precision in source memory Open
Normative word frequency has played a key role in the study of human memory, but there is little agreement as to the mechanism responsible for its effects. To determine whether word frequency affects binding probability or memory precision…
View article: Addenbrooke’s Cognitive Examination III: Psychometric Characteristics and Relations to Functional Ability in Dementia
Addenbrooke’s Cognitive Examination III: Psychometric Characteristics and Relations to Functional Ability in Dementia Open
Objectives: The Addenbrooke’s Cognitive Examination (ACE) is a common cognitive screening test for dementia. Here, we examined the relationship between the most recent version (ACE-III) and its predecessor (ACE-R), determined ACE-III cutof…